Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Kristy K Michael"'
Autor:
Carolyn M. Klinge, Kathleen A. Mattingly, Margarita M. Ivanova, Sharon L. Ripp, Russell A. Prough, Numan Al-Rayyan, Kristy K. Michael Miller
Publikováno v:
Steroids. 78:15-25
Dehydroepiandrosterone (DHEA) levels were reported to associate with increased breast cancer risk in postmenopausal women, but some carcinogen-induced rat mammary tumor studies question this claim. The purpose of this study was to determine how DHEA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::759adbb4517f925de9a6e27e4a4a0336
https://doi.org/10.1016/j.steroids.2012.10.002
https://doi.org/10.1016/j.steroids.2012.10.002
Autor:
Viola Tamasi, Thomas E. Geoghagen, Russell A. Prough, Ermin Vila, Sharon L. Ripp, Kristy K. Michael Miller
Publikováno v:
Molecular Pharmacology. 73:968-976
Dehydroepiandrosterone (DHEA), a C19 human adrenal steroid, activates peroxisome proliferator-activated receptor alpha (PPARalpha) in vivo but does not ligand-activate PPARalpha in transient transfection experiments. We demonstrate that DHEA regulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b12526f3360f51e3d534133ad38ba65
https://doi.org/10.1124/mol.107.036780
https://doi.org/10.1124/mol.107.036780
Autor:
Kristy K. Michael Miller
Dehydroepiandrosterone (DHEA) is a C-19 adrenal steroid and the most abundant circulating hormone in humans. Since circulating levels decline in late adulthood, treatment of humans with DHEA has been suggested to have beneficial health effects. Altho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42c5988d61050551dfa8f5398a6b58ad
https://doi.org/10.18297/etd/975
https://doi.org/10.18297/etd/975
Publikováno v:
Drug Metabolism Reviews. 38:89-116
Dehydroepiandrosterone has been thought to have physiological functions other than as an androgen precursor. The previous studies performed have demonstrated a number of biological effects in rodents, such as amelioration of disease in diabetic, chem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3eda9d1ac4bad34b11fcfb98b740903
https://doi.org/10.1080/03602530600569877
https://doi.org/10.1080/03602530600569877
Autor:
Edward T. Morgan, Chunja Lee, Po-Yung Cheng, Kristy K. Michael Miller, John Y.L. Chiang, Russell A. Prough, David S. Riddick, Asmeen Jahan, Yoav E. Timsit, Sharon L. Ripp, Anahita Bhathena
Publikováno v:
Drug Metabolism and Disposition. 32:367-375
This article is an invited report of a symposium sponsored by the Division for Drug Metabolism of the American Society for Pharmacology and Experimental Therapeutics held at Experimental Biology 2003 in San Diego, California, April 11-15, 2003. Sever
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7083737921ce6e79ffc466210ca416f1
https://doi.org/10.1124/dmd.32.4.367
https://doi.org/10.1124/dmd.32.4.367
Publikováno v:
Archives of Biochemistry and Biophysics. 412:251-258
The cytochrome p450-dependent formation and subsequent interconversion of dehydroepiandrosterone (DHEA) metabolites 7 alpha-hydroxy-DHEA (7 alpha-OH-DHEA), 7 beta-hydroxy-DHEA (7 beta-OH-DHEA), and 7-oxo-DHEA was observed in human, pig, and rat liver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba8a19d6e0e2dee0f9c5a469db650537
https://doi.org/10.1016/s0003-9861(03)00056-0
https://doi.org/10.1016/s0003-9861(03)00056-0
Publikováno v:
Analytical biochemistry. 333(1)
Current research on dehydroepiandrosterone (DHEA) is limited due to lack of radiolabeled metabolites. We utilized pig liver microsomal (PLM) fractions to prepare [(3)H]-labeled 7 alpha-hydroxy-DHEA (7 alpha-OH-DHEA), 7 beta-hydroxy-DHEA (7 beta-OH-DH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b8c5b0ec1e3c680bf64f80a49a311bc
https://pubmed.ncbi.nlm.nih.gov/15351289
https://pubmed.ncbi.nlm.nih.gov/15351289
Autor:
Thomas H. Rushmore, William M. Pierce, Sharon L. Ripp, Russell A. Prough, Jian Cai, Kristy K. Michael Miller
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 32(3)
The purpose of this study was to quantify the oxidative metabolism of dehydroepiandrosterone (3beta-hydroxy-androst-5-ene-17-one; DHEA) by liver microsomal fractions from various species and identify the cytochrome P450 (P450) enzymes responsible for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0eb566f2b54cc303ea470cd1fb946de
https://pubmed.ncbi.nlm.nih.gov/14977864
https://pubmed.ncbi.nlm.nih.gov/14977864
Autor:
Miller, Kristy K. Michael.
Thesis (Ph. D.)--University of Louisville, 2004.
Department of Biochemistry and Molecular Biology. Vita. "May 2004." Includes bibliographical references (leaves 82-96).
Department of Biochemistry and Molecular Biology. Vita. "May 2004." Includes bibliographical references (leaves 82-96).
Externí odkaz:
http://etd.louisville.edu/data/UofL0058d2004.pdf
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