Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kristy G Kuplast"'
Autor:
Jennifer R. Molina, Joseph M. Gozgit, Melissa M. Vasbinder, Ryan P. Abo, Kaiko kunii, Kristy G. Kuplast-Barr, Bin Gui, Sunaina P. Nayak, Elena Minissale, Kerren K. Swinger, Tim J. Wigle, Alvin Z. Lu, Danielle J. Blackwell, Christina R. Majer, Yue Ren, Ellen Bamberg, Mario Niepel, Jan-Rung Mo, William D. Church, Ahmed S. Mady, Jeff Song, Zacharenia A. Varsamis, Luke Utley, Patricia E. Rao, Timoty J. Mitchison, Kevin W. Kuntz, Victoria M. Richon, Kristen McEachern, Heike Keilhack
Publikováno v:
Cancer Research. 82:2154-2154
Targeting cytosolic nucleic acid sensing pathways to activate the Type I interferon (IFN) response is an emerging therapeutic strategy being explored in oncology. The PARP family consists of seventeen enzymes that regulate fundamental biological proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::138b6edb388c9ff28b5c6026a9134c0a
https://doi.org/10.1158/1538-7445.am2022-2154
https://doi.org/10.1158/1538-7445.am2022-2154
Autor:
J. Joshua Smith, Christina R. Majer, Michael John Munchhof, Roy M. Pollock, Nigel J. Waters, Kristy G Kuplast, Lei Jin, L. Danielle Johnston, Lawrence A. Reiter, Nathalie Rioux, Richard Chesworth, Margaret Porter Scott, Elayne Chan-Penebre, P. Ann Boriack-Sjodin, Robert A. Copeland, Mikel P. Moyer, Kenneth W. Duncan
Publikováno v:
ACS medicinal chemistry letters. 7(2)
The recent publication of a potent and selective inhibitor of protein methyltransferase 5 (PRMT5) provides the scientific community with in vivo-active tool compound EPZ015666 (GSK3235025) to probe the underlying pharmacology of this key enzyme. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45a771b83bf95b1122657893267ce967
https://pubmed.ncbi.nlm.nih.gov/26985292
https://pubmed.ncbi.nlm.nih.gov/26985292
Autor:
Jesse Smith, David Soong, Kristy G Kuplast, Christine Thompson, Olena Barbash, Elayne Penebre, Rocio Montes de Oca, Christina R. Majer, Christopher L. Carpenter, Charles F. McHugh, Ryan G. Kruger, Kenneth W. Duncan, Robert A. Copeland, Richard Chesworth, Neil F. Johnson, Sarah Gerhart, Ping Zhang
Publikováno v:
Cancer Research. 75:LB-248
PRMT5 is responsible for symmetric dimethylation of arginine residues in glycine and arginine rich (GAR) motifs on a variety of cytosolic and nuclear proteins including histones, spliceosome components, regulators of translation, transcription factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd47649121ed3b12bab388fda4e64230
https://doi.org/10.1158/1538-7445.am2015-lb-248
https://doi.org/10.1158/1538-7445.am2015-lb-248
Autor:
Wilma Wasco, Kristy G. Kuplast, Nikhat F. Zaidi, Yuji Kajiwara, Kevin J. Washicosky, Joseph D. Buxbaum
Publikováno v:
Journal of neurochemistry. 98(4)
Calsenilin/potassium channel-interacting protein (KChIP)3/ downstream regulatory element sequence antagonist modulator (DREAM) is a neuronal calcium-binding protein that has been shown to have multiple functions in the cell, including the regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ca366a351f6e28b0b92fc7f53186284
https://pubmed.ncbi.nlm.nih.gov/16787403
https://pubmed.ncbi.nlm.nih.gov/16787403