Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics.

Autor: Montserrat Garcia-Closas, Per Hall, Heli Nevanlinna, Karen Pooley, Jonathan Morrison, Douglas A Richesson, Stig E Bojesen, Børge G Nordestgaard, Christen K Axelsson, Jose I Arias, Roger L Milne, Gloria Ribas, Anna González-Neira, Javier Benítez, Pilar Zamora, Hiltrud Brauch, Christina Justenhoven, Ute Hamann, Yon-Dschun Ko, Thomas Bruening, Susanne Haas, Thilo Dörk, Peter Schürmann, Peter Hillemanns, Natalia Bogdanova, Michael Bremer, Johann Hinrich Karstens, Rainer Fagerholm, Kirsimari Aaltonen, Kristiina Aittomäki, Karl von Smitten, Carl Blomqvist, Arto Mannermaa, Matti Uusitupa, Matti Eskelinen, Maria Tengström, Veli-Matti Kosma, Vesa Kataja, Georgia Chenevix-Trench, Amanda B Spurdle, Jonathan Beesley, Xiaoqing Chen, Australian Ovarian Cancer Management Group, Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer, Peter Devilee, Christi J van Asperen, Catharina E Jacobi, Rob A E M Tollenaar, Petra E A Huijts, Jan G M Klijn, Jenny Chang-Claude, Silke Kropp, Tracy Slanger, Dieter Flesch-Janys, Elke Mutschelknauss, Ramona Salazar, Shan Wang-Gohrke, Fergus Couch, Ellen L Goode, Janet E Olson, Celine Vachon, Zachary S Fredericksen, Graham G Giles, Laura Baglietto, Gianluca Severi, John L Hopper, Dallas R English, Melissa C Southey, Christopher A Haiman, Brian E Henderson, Laurence N Kolonel, Loic Le Marchand, Daniel O Stram, David J Hunter, Susan E Hankinson, David G Cox, Rulla Tamimi, Peter Kraft, Mark E Sherman, Stephen J Chanock, Jolanta Lissowska, Louise A Brinton, Beata Peplonska, Maartje J Hooning, Han Meijers-Heijboer, J Margriet Collee, Ans van den Ouweland, Andre G Uitterlinden, Jianjun Liu, Low Yen Lin, Li Yuqing, Keith Humphreys, Kamila Czene, Angela Cox, Sabapathy P Balasubramanian, Simon S Cross, Malcolm W R Reed, Fiona Blows, Kristy Driver, Alison Dunning, Jonathan Tyrer, Bruce A J Ponder, Suleeporn Sangrajrang, Paul Brennan, James McKay, Fabrice Odefrey, Valerie Gabrieau, Alice Sigurdson, Michele Doody, Jeffrey P Struewing, Bruce Alexander, Douglas F Easton, Paul D Pharoah

Publikováno v: PLoS Genetics, Vol 4, Iss 4, p e1000054 (2008)

A three-stage genome-wide association study recently identified single nucleotide polymorphisms (SNPs) in five loci (fibroblast growth receptor 2 (FGFR2), trinucleotide repeat containing 9 (TNRC9), mitogen-activated protein kinase 3 K1 (MAP3K1), 8q24

Externí odkaz: https://doaj.org/article/d83899862e5c4f17a6111d8afac72371

Supplementary Table 3 from TGF-β Signaling Pathway and Breast Cancer Susceptibility

Autor: Alison M. Dunning, James C. Metcalfe, Robin Hesketh, Douglas F. Easton, Paul D. Pharoah, Jolanta Lissowska, Jonine Figueroa, Montserrat Garcia-Closas, Manjeet K. Humphreys, Kristy Driver, Caroline Baynes, Craig Luccarini, Serena Scollen

Supplementary Table 3 from TGF-β Signaling Pathway and Breast Cancer Susceptibility

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::774c8b27454b0920a65328e645cdd48f
https://doi.org/10.1158/1055-9965.22437399.v1

Evidence for a time-dependent association between FOLR1 expression and survival from ovarian carcinoma: implications for clinical testing. An Ovarian Tumour Tissue Analysis consortium study

Autor: Bruce R. Rosen, A. Hartmann, Bo Gao, Georgia Chenevix-Trench, Gregg Nelson, Marcus Q. Bernardini, Carl Morrison, Mercedes Jimenez-Linan, Usha Menon, C Ewanowich, E Benjamin, Joshy George, S Liu, Blaise Clarke, Sian Fereday, Brooke L. Fridley, Allan Jensen, A Gentry-Maharaj, Peter A. Fasching, Suha Deen, Zachary C. Fogarty, Kunle Odunsi, David L. Wachter, Falk Thiel, Simon A. Gayther, Anna deFazio, Shashikant Lele, David D.L. Bowtell, Lara Sucheston, Kristy Driver, James D. Brenton, Michael S. Anglesio, Gary L. Keeney, Helen Steed, Ellen L. Goode, Martin Köbel, Robert A. Vierkant, Alexander Hein, Helen J. Mackay, Linda E. Kelemen, Paul D.P. Pharoah, David G. Huntsman, Sharon E. Johnatty, Amit M. Oza, S.K. Kjaer, S Cho, Martin Widschwendter, Maria P. Intermaggio, Claus Høgdall, Marie Mack, J Madore, Kimberly R. Kalli, Jennifer M Koziak, M. W. Beckmann, Prafull Ghatage, P Shaw, Jennifer Alsop, Estrid Høgdall, Susan J. Ramus, K. Moysich, Wiam Bshara, Laura Galletta

Publikováno v: British Journal of Cancer

Background: Folate receptor 1 (FOLR1) is expressed in the majority of ovarian carcinomas (OvCa), making it an attractive target for therapy. However, clinical trials testing anti-FOLR1 therapies in OvCa show mixed results and require better understan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95e15b1cf7691ba7ce8d304a7c7b01dc
http://europepmc.org/articles/PMC4264456

Prognosis of early breast cancer by immunohistochemistry defined intrinsic sub-types in patients treated with adjuvant chemotherapy in the NEAT/BR9601 trial

Autor: Christopher J. Poole, Paul D.P. Pharoah, Louise Hiller, Kristy Driver, Carlos Caldas, John M. S. Bartlett, Alaa M.G. Ali, Chris Twelves, Janet A. Dunn, Elena Provenzano, Helena M. Earl, Alison F. Munro, Jean Abraham

Publikováno v: International Journal of Cancer. 133:1470-1478

Breast cancer can be classified into molecular sub-types that have distinct survival patterns. We evaluated the prognostic significance of breast cancer sub-types in a cohort of women taking part in the NEAT and BR9601 clinical trials comparing cyclo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::19078484e5c49633175bd5bcbd9e5353
https://doi.org/10.1002/ijc.28150

Associations of Breast Cancer Risk Factors With Tumor Subtypes: A Pooled Analysis From the Breast Cancer Association Consortium Studies

Autor: Gillian S. Dite, Brian E. Henderson, U Hamann, Rulla M. Tamimi, Agnes Jager, Laurence N. Kolonel, J Heinz, Hans Wildiers, Celine M. Vachon, Päivi Heikkilä, Chen-Yang Shen, Laura J. Van 'T Veer, Pasi Hirvikoski, Suleeporn Sangrajrang, James McKay, Päivi Auvinen, Michael Bremer, Ann Smeets, Kamila Czene, William J. Tapper, Peter Hillemanns, Fergus J. Couch, John L. Hopper, Douglas F. Easton, Jose Ignacio Arias Perez, Roger L. Milne, Helen Tsimiklis, Carmel Apicella, Antoinette Hollestelle, Zachary S. Fredericksen, Argyrios Ziogas, Helen Cramp, Melissa C. Southey, Malcolm W.R. Reed, Tjoung Won Park-Simon, Janet E. Olson, Primitiva Menéndez Rodríguez, Robert Winqvist, Fabrice Odefrey, Bohdan Górski, Caroline Seynaeve, Matthew L. Kosel, Valerie Gaborieau, Mia M. Gaudet, Diether Lambrechts, Anna Jakubowska, Paul D.P. Pharoah, Fleur Hammet, Amanda B. Spurdle, Stig E. Bojesen, Thilo Dörk, Victoria Cafourek, Julia A. Knight, Frances P O'Malley, Daniel Connley, Letitia D. Smith, David L. Wachter, Flora E. van Leeuwen, David Dynnes Ørsted, Helene Holland, Sabapathy P. Balasubramanian, Aysun Ay, Tuomas Heikkinen, Jaana M. Kauppinen, Diljit Kaur-Knudsen, Børge G. Nordestgaard, Gord Glendon, Paul Brennan, Jacek Gronwald, Mervi Grip, Elinor J. Sawyer, Kristy Driver, Jan Lubinski, Hoda Anton-Culver, Louise A. Brinton, Veli-Matti Kosma, Mieke Kriege, P. E.A. Huijts, Irene L. Andrulis, P. Zamora, S. Chanock, Pei Ei Wu, Tomasz Byrski, Arja Jukkola-Vuorinen, Peter A. Fasching, Tomasz Huzarski, Hatef Darabi, Andreas Meyer, Raem Tollenaar, Fiona M. Blows, Ian Tomlinson, Xiaohong R. Yang, Dallas R. English, Diana Eccles, Ans M.W. van den Ouweland, Johann H. Karstens, Montserrat Garcia-Closas, Alina Vrieling, Graham G. Giles, Michael J. Kerin, Show Lin Yang, Nicola Miller, Sue Gerty, Thomas Brüning, Christopher A. Haiman, Kari Mononen, Loic Le Marchand, Jyh Cherng Yu, Anna Marie Mulligan, Jenny Chang-Claude, Christian R. Loehberg, Matthias W. Beckmann, Madeleine M.A. Tilanus-Linthorst, Angela Cox, Maartje J. Hooning, Susan E. Hankinson, Gianluca Severi, Angela M. Jones, Heli Nevanlinna, Caroline Weltens, Jolanta Lissowska, Hiltrud Brauch, Giu Cheng Hsu, Sebastian M. Jud, Per Hall, Hans Fischer, Arto Mannermaa, Christina Justenhoven, Laura Baglietto, Katri Pylkäs, Kristiina Aittomäki, Sara Margolin, T. Vandorpe, M. Barile, Ylermi Soini, Beate Pesch, Ellen L. Goode, Nayana Weerasooriya, Peter Devilee, Carl Blomqvist, Margriet Collée, Vesa Kataja, Arndt Hartmann, Manjeet K. Humphreys, Siranoush Manoukian, Annika Lindblom, Marjanka K. Schmidt, Yon Ko, Patrick Neven, Chia-Ni Hsiung, Xianshu Wang, Keith Humphreys, Dieter Flesch-Janys, Niall M. McInerney, Javier Benítez, Esther M. John, Jianjun Liu, Peter Sinn, Reijo Sironen, Annegien Broeks, Rebecca Hein, Shou Tung Chen, Paolo Radice, Simon S. Cross, Mark E. Sherman, Robert Paridaens, Shan Wang-Gohrke, Sebastian B. Weihbrecht, Jonine D. Figueroa, Catriona McLean, Georgia Chenevix-Trench, David J. Hunter, Henrik Flyger, Beata Peplonska

Publikováno v: Yang, X R, Chang-Claude, J, Goode, E L, Couch, F J, Nevanlinna, H, Milne, R L, Gaudet, M, Schmidt, M K, Broeks, A, Cox, A, Fasching, P A, Hein, R, Spurdle, A B, Blows, F, Driver, K, Flesch-Janys, D, Heinz, J, Sinn, P, Vrieling, A, Heikkinen, T, Aittomaki, K, Heikkila, P, Blomqvist, C, Lissowska, J, Peplonska, B, Chanock, S, Figueroa, J, Brinton, L, Hall, P, Czene, K, Humphreys, K, Darabi, H, Liu, J J, van 't Veer, L J, van Leeuwen, F E, Andrulis, I L, Glendon, G, Knight, J A, Mulligan, A M, O'Malley, F P, Weerasooriya, N, John, E M, Beckmann, M W, Hartmann, A, Weihbrecht, S B, Wachter, D L, Jud, S M, Loehberg, C R, Baglietto, L, English, D R, Giles, G G, McLean, C A, Severi, G, Lambrechts, D, Vandorpe, T, Weltens, C, Paridaens, R, Smeets, A, Neven, P, Wildiers, H, Wang, X S, Olson, J E, Cafourek, V, Fredericksen, Z, Kosel, M, Vachon, C, Cramp, H E, Connley, D, Cross, S S, Balasubramanian, S P, Reed, M W R, Dork, T, Bremer, M, Meyer, A, Karstens, J H, Ay, A, Park-Simon, T W, Hillemanns, P, Perez, J I A, Rodriguez, P M, Zamora, P, Bentez, J, Ko, Y D, Fischer, H P, Hamann, U, Pesch, B, Bruning, T, Justenhoven, C, Brauch, H, Eccles, D M, Tapper, W J, Gerty, S M, Sawyer, E J, Tomlinson, I P, Jones, A, Kerin, M, Miller, N, McInerney, N, Anton-Culver, H & Garcia-Closas, M 2011, ' Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the breast cancer association consortium studies ', Journal of the National Cancer Institute, vol. 103, no. 3, pp. 250-263 . https://doi.org/10.1093/jnci/djq526
JNCI Journal of the National Cancer Institute; Vol 103
Journal of the National Cancer Institute, 103(3), 250-263. Oxford University Press
JNCI: Journal of the National Cancer Institute, 103(3), 250-63
Yang, Xiaohong R; Chang-Claude, Jenny; Goode, Ellen L; Couch, Fergus J; Nevanlinna, Heli; Milne, Roger L; et al.(2011). Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies.. Journal of the National Cancer Institute, 103(3), 250-263. doi: 10.1093/jnci/djq526. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/8bh793dt
JOURNAL OF THE NATIONAL CANCER INSTITUTE, 103(3), 250-263. Oxford University Press

BACKGROUND: Previous studies have suggested that breast cancer risk factors are associated with estrogen receptor (ER) and progesterone receptor (PR) expression status of the tumors. METHODS: We pooled tumor marker and epidemiological risk factor dat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57462cb9451d4a5dda605873716e0410
https://doi.org/10.1093/jnci/djq526