Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Kristy A, Zera"'
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-13 (2021)
Abstract Background Patients with chronic inflammatory disorders such as inflammatory bowel disease frequently experience neurological complications including epilepsy, depression, attention deficit disorders, migraines, and dementia. However, the me
Externí odkaz:
https://doaj.org/article/5d51c9a6793745b090d33b2082300790
Autor:
Kristy A Zera, Neda Bidoki, Huda Nassar, Lauren Drag, Michael Mlynash, Elizabeth Osborn, Muhith Musabbir, Da Eun Kim, Maria Mendez, Maarten Lansberg, Nima Aghaeepour, Marion S Buckwalter
Publikováno v:
Alzheimer's & Dementia. 18
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-13 (2021)
Journal of Neuroinflammation
Journal of Neuroinflammation
BackgroundPatients with chronic inflammatory disorders such as inflammatory bowel disease frequently experience neurological complications including epilepsy, depression, attention deficit disorders, migraines, and dementia. However, the mechanistic
Autor:
Kristy A Zera, Neda H Bidoki, Huda Nassar, Lauren Drag, Michael Mlynash, elizabeth osborn, Muhith Musabbir, Da Eun Kim, Maria Mendez, Maarten G Lansberg, Nima Aghaeepour, Marion S Buckwalter
Publikováno v:
Stroke. 53
Introduction: Depression is common after stroke, and is a debilitating factor undermining recovery in approximately one third of stroke survivors. It is essential to understand the underlying mechanisms to develop better treatments. Such insight may
Autor:
Marion S. Buckwalter, Kristy A. Zera
Publikováno v:
Immunity
The precise mechanisms underlying the beneficial effects of regulatory T (Treg) cells on long-term tissue repair remain elusive. Here, using single-cell RNA sequencing and flow cytometry, we found that Treg cells infiltrated the brain 1–5 weeks aft
Autor:
Hanadie Yousef, Benoit Lehallier, Taylor Merkel, Marion S. Buckwalter, Michelle B. Chen, Tony Wyss-Coray, Vidhu Mathur, Andrew C. Yang, Kristy A. Zera, Ashley N Burke, Ramesh V. Nair, Markus Schwaninger, Elisabeth Berber, Eugene C. Butcher, Husein Hadeiba, Stephen R. Quake, Todd C. Peterson, Liana Bonanno, Cathrin J. Czupalla, Jakob Körbelin, Davis P. Lee, Judith Zandstra
Publikováno v:
Nature Medicine. 25:988-1000
An aged circulatory environment can activate microglia, reduce neural precursor cell activity and impair cognition in mice. We hypothesized that brain endothelial cells (BECs) mediate at least some of these effects. We observe that BECs in the aged m
Autor:
Marion S. Buckwalter, Kristy A. Zera
Publikováno v:
Neurotherapeutics
The immune response to stroke is an exciting target for future stroke therapies. Stroke is a leading cause of morbidity and mortality worldwide, and clot removal (mechanical or pharmacological) to achieve tissue reperfusion is the only therapy curren
Autor:
Todd C. Peterson, Davis P. Lee, Hanadie Youdef, Tony Wyss-Coray, Marion S. Buckwalter, Kristy A. Zera
Publikováno v:
Stroke. 51
Background: Ischemia-induced neuroinflammmation is associated with worse outcomes after stroke. The innate immune response can mediate infarct expansion and impair short-term recovery, while adaptive responses lead to chronic neuroinflammation, neuro
Publikováno v:
Gene. 595:212-220
Ensuring continuous intracellular supply of thiamine is essential to maintain metabolism. Cellular homeostasis requires the function of the membrane bound thiamine transporters THTR1 and THTR2. In the absence of increased dietary intake of thiamine,
Autor:
Kristy A. Zera, Jason Zastre
Publikováno v:
Toxicology and applied pharmacology. 355
Vitamin B1, or thiamine is a critical enzyme cofactor required for metabolic function and energy production. Thiamine deficiency (TD) is common in various diseases, and results in severe neurological complications due to diminished mitochondrial func