Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Kristy, O'Donnell"'
Autor:
Simon N. Willis, Julie Tellier, Yang Liao, Stephanie Trezise, Amanda Light, Kristy O’Donnell, Lee Ann Garrett-Sinha, Wei Shi, David M. Tarlinton, Stephen L. Nutt
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Although important for early development, PU.1 is dispensable for mature B cell function, possibly owing to compensation by the related transcription factor SpiB. Here the authors show PU.1 and SpiB are collectively required for humoral immunity, thr
Externí odkaz:
https://doaj.org/article/37dfa3d4d0b943728cbf40939c1d7a57
Autor:
Simona Infantino, Amanda Light, Kristy O’Donnell, Vanessa Bryant, Danielle T. Avery, Michael Elliott, Stuart G. Tangye, Gabrielle Belz, Fabienne Mackay, Stephane Richard, David Tarlinton
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
PRMT1 is an arginine methyltransferase involved in a variety of cell functions. Here the authors delete PRMT1 specifically in mature B cells to show the importance of arginine methylation for B cell proliferation, differentiation and survival, and th
Externí odkaz:
https://doaj.org/article/f43684f73c68477f96647f41ab02832e
Autor:
Dana Piovesan, Jessica Tempany, Andrea Di Pietro, Inge Baas, Callisthenis Yiannis, Kristy O’Donnell, Yunshun Chen, Victor Peperzak, Gabrielle T. Belz, Charles R. Mackay, Gordon K. Smyth, Joanna R. Groom, David M. Tarlinton, Kim L. Good-Jacobson
Publikováno v:
Cell Reports, Vol 19, Iss 3, Pp 461-470 (2017)
Summary: Humoral immune responses are tailored to the invading pathogen through regulation of key transcription factors and their networks. This is critical to establishing effective antibody-mediated responses, yet it is unknown how B cells integrat
Externí odkaz:
https://doaj.org/article/3c81bb09b0d54bd388012d93887c7861
Autor:
Michael Sze Yuan Low, Erica J. Brodie, Pasquale L. Fedele, Yang Liao, George Grigoriadis, Andreas Strasser, Axel Kallies, Simon N. Willis, Julie Tellier, Wei Shi, Sarah Gabriel, Kristy O’Donnell, Catherine Pitt, Stephen L. Nutt, David Tarlinton
Publikováno v:
Cell Reports, Vol 29, Iss 9, Pp 2634-2645.e5 (2019)
Summary: The transcription factor interferon regulatory factor 4 (IRF4) is critical for the development, maintenance, and function of plasma cells. The mechanism by which IRF4 exerts its action in mature plasma cells has been elusive due to the death
Externí odkaz:
https://doaj.org/article/2e3ad701df4e46b6a95d81eadca8710a
Autor:
Marcus James Robinson, Zhoujie Ding, Mark R. Dowling, Danika L. Hill, Rosela H. Webster, Craig McKenzie, Catherine Pitt, Kristy O’Donnell, Jesse Mulder, Erica Brodie, Philip D. Hodgkin, Nick C. Wong, Isaak Quast, David M. Tarlinton
Publikováno v:
Immunity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adf53b001bdce44f7a189d6bf013b908
https://doi.org/10.1016/j.immuni.2023.04.015
https://doi.org/10.1016/j.immuni.2023.04.015
Autor:
Tabinda Hussain, Christopher D. Scharer, Uri Hershberg, Kristy O'Donnell, Kim L. Good-Jacobson, Tian Mi, Simon Preston, Amy W. Chung, Areen Shtewe, Timon Damelang, Nicole L. La Gruta, Jack Polmear, Lucy Cooper, Stephen J. Turner, Andrea Di Pietro, Vibha A V Udupa, David M. Tarlinton, Lauren Hailes
Publikováno v:
Nature Immunology. 23:86-98
Ineffective antibody-mediated responses are a key characteristic of chronic viral infection. However, our understanding of the intrinsic mechanisms that drive this dysregulation are unclear. Here, we identify that targeting the epigenetic modifier BM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f503b74ae3c6593ff9da610908e3ccb
https://doi.org/10.1038/s41590-021-01077-y
https://doi.org/10.1038/s41590-021-01077-y
Autor:
Marcus James Robinson, Mark R. Dowling, Catherine Pitt, Kristy O’Donnell, Rosela H. Webster, Danika L. Hill, Zhoujie Ding, Alexandra R. Dvorscek, Erica J. Brodie, Philip D. Hodgkin, Isaak Quast, David Mathew Tarlinton
Publikováno v:
Science immunology. 7(76)
Vaccines work largely by generating long-lived plasma cells (LLPCs), but knowledge of how such cells are recruited is sparse. Although it is clear that LLPCs preferentially originate in germinal centers (GCs) and relocate to survival niches in bone m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e7a3fb7947612140846a018910f0f6d
https://pubmed.ncbi.nlm.nih.gov/36306370
https://pubmed.ncbi.nlm.nih.gov/36306370
Autor:
Alexandra R Dvorscek, Craig I McKenzie, Marcus J Robinson, Zhoujie Ding, Catherine Pitt, Kristy O'Donnell, Dimitra Zotos, Robert Brink, David M Tarlinton, Isaak Quast
Publikováno v:
EMBO reports. 23
The proliferation and differentiation of antigen-specific B cells, including the generation of germinal centers (GC), are prerequisites for long-lasting, antibody-mediated immune protection. Affinity for antigen determines B cell recruitment, prolife
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::440dba50bef9d75f935f4d4e4c8ee7a7
https://doi.org/10.15252/embr.202254677
https://doi.org/10.15252/embr.202254677
Autor:
Alexandra R. Dvorscek, Craig I. McKenzie, Marcus J. Robinson, Zhoujie Ding, Catherine Pitt, Kristy O’Donnell, Dimitra Zotos, Robert Brink, David M. Tarlinton, Isaak Quast
The proliferation and differentiation of antigen-specific B cells, including the generation of germinal centers (GC), are prerequisites for long-lasting, high-affinity antibody-mediated immune protection. Affinity for antigen determines B cell recrui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e30cdf122b624b90ebb59838e2ef1740
https://doi.org/10.1101/2022.01.21.476732
https://doi.org/10.1101/2022.01.21.476732
Autor:
Andreas Strasser, Yang Liao, Catherine Pitt, Stephen L. Nutt, David M. Tarlinton, Kristy O'Donnell, Erica J. Brodie, Pasquale L. Fedele, Sarah S. Gabriel, Axel Kallies, Simon N. Willis, Wei Shi, Julie Tellier, George Grigoriadis, Michael Sze Yuan Low
Publikováno v:
Cell Reports, Vol 29, Iss 9, Pp 2634-2645.e5 (2019)
Summary: The transcription factor interferon regulatory factor 4 (IRF4) is critical for the development, maintenance, and function of plasma cells. The mechanism by which IRF4 exerts its action in mature plasma cells has been elusive due to the death
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e91fc09876d8d34355d8bdb55f0e179
http://www.sciencedirect.com/science/article/pii/S2211124719314305
http://www.sciencedirect.com/science/article/pii/S2211124719314305