Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Kristos I. Negrón Terón"'
Autor:
Kedar Puvar, Shalini Iyer, Jiaqi Fu, Sebastian Kenny, Kristos I. Negrón Terón, Zhao-Qing Luo, Peter S. Brzovic, Rachel E. Klevit, Chittaranjan Das
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
The Legionella pneumophila effector MavC inhibits the human ubiquitin-conjugating enzyme Ube2N. Here, the authors combine NMR, X-ray crystallography and biochemical assays and show that MavC catalyses the intramolecular transglutaminase reaction betw
Externí odkaz:
https://doaj.org/article/648e9d96e29748c9b52e0dbcb435943c
Autor:
Shalini Iyer, Rachel E. Klevit, Kedar Puvar, Jiaqi Fu, Kristos I. Negrón Terón, Sebastian Kenny, Zhao-Qing Luo, Peter S. Brzovic, Chittaranjan Das
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Nature Communications
The bacterial effector MavC modulates the host immune response by blocking Ube2N activity employing an E1-independent ubiquitin ligation, catalyzing formation of a γ-glutamyl-ε-Lys (Gln40Ub-Lys92Ube2N) isopeptide crosslink using a transglutaminase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41de0fd530ca141f8002f08c7cb6647d
https://doi.org/10.1038/s41467-020-16211-x
https://doi.org/10.1038/s41467-020-16211-x