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pro vyhledávání: '"Kristopher Veo"'
Autor:
Kristopher Veo, Robert M. Dores, Emily Moser, Liang Liang, Christina Reinick, Joseph K. Angleson
Publikováno v:
General and Comparative Endocrinology. 172:3-9
The melanocortin 2 receptor (MC2R) is unique in terms of ligand selectivity and in vitro expression in mammalian cell lines as compared to the other four mammalian MCRs. It is well established that ACTH is the only melanocortin ligand that can activa
Autor:
Madhavika N. Serasinghe, Christina Reinick, Joseph K. Angleson, Patricia M. Hinkle, Liang Liang, Robert M. Dores, Kristopher Veo, Lauren Eagelston, Julien A. Sebag
Publikováno v:
General and comparative endocrinology. 174(1)
Analysis of the functional expression of the melanocortin 2 receptor (MC2R) from a rather broad spectrum of vertebrates indicates that MC2R is exclusively selective for the ligand, ACTH, and the melanocortin receptor accessory protein 1 (MRAP1) is re
Publikováno v:
General and comparative endocrinology. 172(1)
The mouse α-TC1.9 endocrine cell line was used to analyze the amino acid requirements for endoproteolytic processing at the paired basic amino acid cleavage site, K 141 R 142 that is N-terminal to the ACTH sequence in the POMC proprotein of the anur