Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Kristopher R Bosse"'
Autor:
Paul M Sondel, Amy K Erbe, Daniel Martinez, Samantha N Buongervino, Kristopher R Bosse, Guillem Pascual-Pasto, Brendan McIntyre, Rawan Shraim, Doncho V Zhelev, Shakhnozakhon Sadirova, Anna M Giudice, Laura Garcia-Gerique, Dimiter S Dimitrov
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 12 (2022)
Background Antibody–drug conjugates (ADCs) that deliver cytotoxic drugs to tumor cells have emerged as an effective and safe anticancer therapy. ADCs may induce immunogenic cell death (ICD) to promote additional endogenous antitumor immune response
Externí odkaz:
https://doaj.org/article/01e319d8e2634ac2869c9e31926d7548
Autor:
David M Barrett, Daniel Martinez, Tiffany Smith, Jessica B Foster, Crystal Griffin, Jo Lynne Rokita, Allison Stern, Cameron Brimley, Komal Rathi, Maria V Lane, Samantha N Buongervino, Peter J Madsen, Alberto Delaidelli, Poul H Sorensen, Robert J Wechsler-Reya, Katalin Karikó, Phillip B Storm, Adam C Resnick, John M Maris, Kristopher R Bosse
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 9 (2022)
Background Pediatric brain tumors are the leading cause of cancer death in children with an urgent need for innovative therapies. Glypican 2 (GPC2) is a cell surface oncoprotein expressed in neuroblastoma for which targeted immunotherapies have been
Externí odkaz:
https://doaj.org/article/e7606fcfe47343a78a08e0f4943daef3
Autor:
Guillem Pascual-Pasto, Brendan McIntyre, Margaret G. Hines, Anna M. Giudice, Laura Garcia-Gerique, Jennifer Hoffmann, Pamela Mishra, Stephanie Matlaga, Simona Lombardi, Rawan Shraim, Patrick M. Schürch, Mark Yarmarkovich, Ted J. Hofmann, Fatemeh Alikarami, Daniel Martinez, Matthew Tsang, Luis Gil-de-Gómez, Timothy T. Spear, Kathrin M. Bernt, Adam J. Wolpaw, Dimiter S. Dimitrov, Wei Li, Kristopher R. Bosse
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Novel chimeric antigen receptor (CAR) T-cell approaches are needed to improve therapeutic efficacy in solid tumors. High-risk neuroblastoma is an aggressive pediatric solid tumor that expresses cell-surface GPC2 and GD2 with a tumor microenv
Externí odkaz:
https://doaj.org/article/b2ad4e5f753a46548b7df6730192b457
Autor:
Robyn T. Sussman, Jo Lynne Rokita, Kevin Huang, Pichai Raman, Komal S. Rathi, Daniel Martinez, Kristopher R. Bosse, Maria Lane, Lori S. Hart, Tricia Bhatti, Bruce Pawel, John M. Maris
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
We developed a computational pipeline designed to use RNA sequencing (n = 136) and gene expression profiling (n = 250) data from neuroblastoma tumors to identify cell surface proteins predicted to be highly expressed in MYCN amplified neuroblastomas
Externí odkaz:
https://doaj.org/article/92b8399491b14034a7ca4fb04570dc8f
Autor:
Yael P. Mossé, John M. Maris, Geoffrey R. Oxnard, Marni Brisson Tierno, Marilyn M. Li, Matthew L. Margolis, Xin Liu, Megan Friedrichsen, Jennifer Stundon, Alexander A. Daniels, Esther R. Berko, Jennifer Saggio, Maria Gemino-Borromeo, Adam Hyman, Alana Fitzsimmons, Sriyaa Suresh, Samantha N. Buongervino, Guillem Pascual-Pasto, Patrick M. Schürch, Brendan McIntyre, Maria V. Lane, Anna Maria Giudice, Kristopher R. Bosse
Supplementary Data from Serial Profiling of Circulating Tumor DNA Identifies Dynamic Evolution of Clinically Actionable Genomic Alterations in High-Risk Neuroblastoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27d61f8b32d4c4f1b5a8baa78624d428
https://doi.org/10.1158/2159-8290.22541887
https://doi.org/10.1158/2159-8290.22541887
Autor:
John M. Maris, Irmgard Irminger-Finger, Eric F. Rappaport, Hakon Hakonarson, Marcella Devoto, Bruce R. Pawel, Mario Capasso, Robert C. Seeger, Shahab Asgharzadeh, Yongqiang Zhang, Eva Dizin, Vanessa Pineros, Yael P. Mosse, Edward F. Attiyeh, Cuiping Hou, Maura Diamond, Cynthia Winter, Michael Laquaglia, Jayanti Jagannathan, Le B. Nguyen, Geoffrey Norris, Robert W. Schnepp, Andrew C. Wood, Kristina A. Cole, Sharon J. Diskin, Kristopher R. Bosse
PDF file - 189K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::025970ef02f65927422cd7b5d5838673
https://doi.org/10.1158/0008-5472.22392186.v1
https://doi.org/10.1158/0008-5472.22392186.v1
Autor:
Michael P. Randall, Laura E. Egolf, Zalman Vaksman, Minu Samanta, Matthew Tsang, David Groff, J. Perry Evans, Jo Lynne Rokita, Mehdi Layeghifard, Adam Shlien, John M. Maris, Sharon J. Diskin, Kristopher R. Bosse
Publikováno v:
bioRxiv
ImportanceHigh-risk neuroblastoma is a complex genetic disease that is lethal in 50% of patients despite intense multimodal therapy. Our genome-wide association study (GWAS) identified single-nucleotide polymorphisms (SNPs) within theBARD1gene showin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f1b4121242b4388101ea51629f113df
https://europepmc.org/articles/PMC9915690/
https://europepmc.org/articles/PMC9915690/
Autor:
Kristopher R. Bosse, Laurence C. Eisenlohr, Nikolaos G. Sgourakis, Nathan M. Kendsersky, Rasika Premaratne, David Groff, Helena Shen, Daniel Martinez, Sarvind Tripathi, Tiffany Noel, John M. Maris, Rebecca Weisberg, Son Nguyen, Jugmohit S. Toor, Mark Yarmarkovich, John M. Warrington, Nicole L. Church, Stefan Stevanovic, Quinlen F. Marshall, Ben R. Kiefel, Erin Runbeck, Hau Truong, Alvin Farrel, Wei Li, Amber K. Weiner, Molly Christie, Moreno Di Marco, Dimiter S. Dimitrov
Publikováno v:
Nature
The majority of oncogenic drivers are intracellular proteins, thus constraining their immunotherapeutic targeting to mutated peptides (neoantigens) presented by individual human leukocyte antigen (HLA) allotypes1. However, most cancers have a modest
Autor:
Samantha Buongervino, Kristopher R. Bosse, Doncho V. Zhelev, Maria Lane, Dimiter S. Dimitrov, Emily Garrigan
Publikováno v:
Mol Cancer Ther
Antibody–drug conjugates (ADC) are a targeted cancer therapy that utilize the specificity of antibodies to deliver potent drugs selectively to tumors. Here we define the complex interaction among factors that dictate ADC efficacy in neuroblastoma b
Autor:
Jessica B Foster, Crystal Griffin, Jo Lynne Rokita, Allison Stern, Cameron Brimley, Komal Rathi, Maria V Lane, Samantha N Buongervino, Tiffany Smith, Peter J Madsen, Daniel Martinez, Alberto Delaidelli, Poul H Sorensen, Robert J Wechsler-Reya, Katalin Karikó, Phillip B Storm, David M Barrett, Adam C Resnick, John M Maris, Kristopher R Bosse
Publikováno v:
Journal for immunotherapy of cancer. 10(9)
BackgroundPediatric brain tumors are the leading cause of cancer death in children with an urgent need for innovative therapies. Glypican 2 (GPC2) is a cell surface oncoprotein expressed in neuroblastoma for which targeted immunotherapies have been d