Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kristopher Kramp"'
Autor:
Yiyuan Yuan, Pengxiu Cao, Mark A Smith, Kristopher Kramp, Ying Huang, Naoki Hisamoto, Kunihiro Matsumoto, Maria Hatzoglou, Hui Jin, Zhaoyang Feng
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e22354 (2011)
Mutation of leucine-rich repeat kinase 2 (LRRK2) is the leading genetic cause of Parkinson's Disease (PD), manifested as age-dependent dopaminergic neurodegeneration, but the underlying molecular mechanisms remain unclear. Multiple roles of LRRK2 may
Externí odkaz:
https://doaj.org/article/1b56426367c34cfa88414ff253b1203b
Publikováno v:
FEBS Letters. 590:3669-3680
Soluble guanylyl cyclase (sGC) plays a crucial role in cyclic nucleotide signaling that regulates numerous important physiological processes. To identify new sGC inhibitors that may prevent the formation of the active catalytic domain conformation, w
Autor:
Wenyu Sun, Hui Jin, Kristopher Kramp, David Salom, Zhaoyang Feng, Krzysztof Palczewski, Beata Jastrzebska, Pengxiu Cao
Publikováno v:
The FASEB Journal. 26:492-502
New strategies for expression, purification, functional characterization, and structural determination of membrane-spanning G-protein-coupled receptors (GPCRs) are constantly being developed because of their importance to human health. Here, we repor
Autor:
Zhaoyang Feng, Maria Hatzoglou, Naoki Hisamoto, Hui Jin, Kristopher Kramp, Yiyuan Yuan, Mark A. Smith, Pengxiu Cao, Kunihiro Matsumoto, Ying Huang
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e22354 (2011)
PLoS ONE
PLoS ONE
Mutation of leucine-rich repeat kinase 2 (LRRK2) is the leading genetic cause of Parkinson's Disease (PD), manifested as age-dependent dopaminergic neurodegeneration, but the underlying molecular mechanisms remain unclear. Multiple roles of LRRK2 may
Autor:
Susanne B. Nicholas, Sharon G. Adler, Madeleine V. Pahl, Rulan S. Parekh, Josef Coresh, Sudha K. Iyengar, Barry I. Freedman, Orly F. Kohn, Jasmin Divers, Yvette Berthier-Schaad, Matthew R. Weir, Michael W. Smith, Jeffrey R. Schelling, John H. Sadler, Nick Patterson, Hanna E. Abboud, David Reich, John R. Sedor, Nancy E. Fink, William C. Knowler, Arti Tandon, Denyse Thornley-Brown, Man Li, Michael J. Klag, Lucy A. Meoni, David J. Leehey, Cheryl A. Winkler, W. H. Linda Kao, Kristopher Kramp, Paul L. Kimmel, Neil R. Powe
Publikováno v:
Nature genetics. 40(10)
Linda Kao and colleagues use admixture mapping to identify risk variants in MYH9 associated with nondiabetic end-stage renal disease in African Americans. The risk variants are more common in populations with West African ancestry and contribute to t
Autor:
M. Budgett, L. Hernandez, Eli Ipp, Carol Fondran, A. Pickens, B. S. Kasinath, Michael F. Seldin, V. Turner, R. Juan, H. Abboud, J. Schelling, Philip G Zager, C. Brown, B. Kessing, C. Winkler, Y. D I Chen, S. J. O'Brien, D. W. Bowden, Gyungah Jun, L. Jones, J. Gonzalez, E. Zaletel, Katrina A.B. Goddard, M. W. Smith, Amanda Horvath, L. Getz-Fradley, X. Guo, T. Whitehead, H. Li, L. M. Phillips, Jane M. Olson, J. Chester, Robert L. Hanson, T. Abboud, Michael J. Klag, Marina Scavini, K. Ngo, K. Taylor, L. Mead, O. Kohn, R. Lovelace, Paul L. Kimmel, William C. Knowler, R. Spielman, B. Waseta, C. Muro, L. Humbert, Mohammed F. Saad, R. Young, Vallabh O. Shah, I. Sili, C. Garcia, Madeleine V. Pahl, C. Jefferson, Sharon G. Adler, Robert C. Elston, Rulan S. Parekh, Sudha K. Iyengar, J. R. Sedor, Jerome I. Rotter, Denyse Thornley-Brown, Janine La Page, M. Thompson, J. Wolford, Josephine P. Briggs, L. Ingram-Drake, J. Sewemaenewa, D. Leehey, A. Bobelu, R. Chakraborty, C. Goyes, N. Arar, H. E. Collins-Schramm, R. G. Nelson, C. Pagliasotti, S. C. Satko, S. Viverette, R. L. Hanson, F. Hariri, S. Warren, S. Nicholas, J. Loebel, M. Slaughter, R. Plaetke, G. Brooks, G. Barone, Sarah Ialacci, M. Spainhour, G. M. Dunston, V. Sartorio, M. Stern, S. Edwards-Quade, David G. Warnock, W. H. Linda Kao, Kristopher Kramp, S. S. Rich, B. I. Freedman, B. Walker, C. Jenkinson, Lucy A. Meoni, R. Duggirala, C. Luethe, Rebekah S. Rasooly
Publikováno v:
Clinical journal of the American Society of Nephrology : CJASN. 2(6)
Background and objectives: This study investigated the effect of long-term storage at 70°C on urinary albumin, protein, and creatinine measurements in the Family Investigation of Nephropathy and Diabetes, a multicenter study designed to identify gen