Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kristopher J Schmit"'
Autor:
Kristopher J. Schmit, Pierre Garcia, Alessia Sciortino, Velma T.E. Aho, Beatriz Pardo Rodriguez, Mélanie H. Thomas, Jean-Jacques Gérardy, Irati Bastero Acha, Rashi Halder, Camille Cialini, Tony Heurtaux, Irina Ostahi, Susheel B. Busi, Léa Grandmougin, Tuesday Lowndes, Yogesh Singh, Eric C. Martens, Michel Mittelbronn, Manuel Buttini, Paul Wilmes
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113071- (2023)
Summary: Parkinson’s disease (PD) is a neurological disorder characterized by motor dysfunction, dopaminergic neuron loss, and alpha-synuclein (αSyn) inclusions. Many PD risk factors are known, but those affecting disease progression are not. Life
Externí odkaz:
https://doaj.org/article/c8ff2342a7c34ecfa2de37f394f441e9
Autor:
Kristopher J Schmit, Alessia Sciortino, Velma TE Aho, Pierre Garcia, Beatriz Pardo Rodriguez, Melanie H Thomas, Jean-Jacques Gerardy, Rashi Halder, Camille Cialini, Tony Heurtaux, Irati Bastero Acha, Irina Ostahi, Eric C Martens, Michel Mittelbronn, Manuel Buttini, Paul Wilmes
The microbiome-gut-brain axis has been proposed as a pathogenic path in Parkinson's disease (PD). Dietary driven dysbiosis and reduced gut barrier function could facilitate the interaction of toxic external or internal factors with the enteric nervou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d3e49d98a53c8707291175d8b744731
https://doi.org/10.1101/2022.03.21.485143
https://doi.org/10.1101/2022.03.21.485143
Autor:
Pierre Garcia, Wiebke Jürgens‐Wemheuer, Oihane Uriarte Huarte, Alessandro Michelucci, Annette Masuch, Simone Brioschi, Andreas Weihofen, Eric Koncina, Djalil Coowar, Tony Heurtaux, Enrico Glaab, Rudi Balling, Carole Sousa, Tony Kaoma, Nathalie Nicot, Tatjana Pfander, Walter Schulz‐Schaeffer, Ahmad Allouche, Nicolas Fischer, Knut Biber, Felix Kleine‐Borgmann, Michel Mittelbronn, Marek Ostaszewski, Kristopher J. Schmit, Manuel Buttini
Background: Akey process of neurodegeneration in Parkinson’s disease (PD) is the transneuronal spreading of a-synuclein. Alpha-synuclein is a presynaptic protein that is implicated in the pathogenesis of PD and other synucleinopathies, where it for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88537d06b41a2c229001a60d01e5d9bb
http://orbilu.uni.lu/handle/10993/50437
http://orbilu.uni.lu/handle/10993/50437
Autor:
Pierre Garcia, Wiebke Jürgens-Wemheuer, Oihane Uriarte, Kristopher J Schmit, Annette Masuch, Simone Brioschi, Andreas Weihofen, Eric Koncina, Djalil Coowar, Tony Heurtaux, Enrico Glaab, Rudi Balling, Carole Sousa, Alessandro Michelucci, Tony Kaoma, Nathalie Nicot, Tatjana Pfander, Walter Schulz-Schaeffer, Ahmad Allouche, Nicolas Fischer, Knut Biber, Michel Mittelbronn, Manuel Buttini
A key process of neurodegeneration in Parkinson’s disease (PD) is the transneuronal spreading of α-synuclein. Alpha-synuclein is a presynaptic protein that is implicated in the pathogenesis of PD and other synucleinopathies, where it forms, upon i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26285bc982d5edfdfab09af9ce370809
https://doi.org/10.1101/2020.08.05.237750
https://doi.org/10.1101/2020.08.05.237750
Autor:
Diana M. Hendrickx, Nathalie Nicot, Manuel Buttini, Heike Kollmus, Tony Kaoma, Enrico Glaab, Alessia Sciortino, Kristopher J Schmit, Pierre Garcia, Amer Ashrafi, Laurent Vallar
Publikováno v:
Molecular neurobiology
United States
Molecular Neurobiology
United States
Molecular Neurobiology
Understanding Parkinson’s disease (PD), in particular in its earliest phases, is important for diagnosis and treatment. However, human brain samples are collected post-mortem, reflecting mainly end-stage disease. Because brain samples of mouse mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46c520d0b4c7c1e0ab23fd44e8b3c1ea