Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Kristopher A Lofgren"'
Autor:
Matías J. Dahl, Kristopher A. Lofgren, Cleo Haugen, Gil E. Harmon, Sarah P. Hughes, Karen D. Cowden Dahl
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Uterine carcinosarcoma (UCS) is a rare but aggressive endometrial cancer. Survival outcomes for women diagnosed with UCS remain poor with lower survival than those of endometrioid or high-grade serous uterine cancers. The histopathological hallmark o
Externí odkaz:
https://doaj.org/article/a5d87c31f11b475ebae3d13f1d624031
Publikováno v:
Antibody Therapeutics. 5:226-231
Amphiregulin (AREG) is a transmembrane protein which, following TACE/ADAM17-dependent cleavage, releases a soluble Epidermal Growth Factor Receptor ligand domain that promotes proliferation of normal and malignant cells. Expression of Amphiregulin ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e19c240f10ac2df11dd3f0b14d36d222
https://doi.org/10.1093/abt/tbac020
https://doi.org/10.1093/abt/tbac020
Autor:
Paraic A. Kenny, Maryia Barnett, Evelyn Aranda, Hui Liu, Natasha Chandiramani, Kristopher A. Lofgren, Edmund C. Jenkins, Esther A. Peterson
Additional representative examples of Amphiregulin immunostaining in breast cancer specimens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::134e982a6eacb661815f442dbd875e71
https://doi.org/10.1158/0008-5472.22411058.v1
https://doi.org/10.1158/0008-5472.22411058.v1
Autor:
Paraic A. Kenny, Maryia Barnett, Evelyn Aranda, Hui Liu, Natasha Chandiramani, Kristopher A. Lofgren, Edmund C. Jenkins, Esther A. Peterson
Estrogen stimulation promotes epithelial cell proliferation in estrogen receptor (ERα)-positive breast cancer. Many ERα target genes have been enumerated, but the identities of the key effectors mediating the estrogen signal remain obscure. During
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5733b2c648d7903df14893d0e943c957
https://doi.org/10.1158/0008-5472.c.6508142
https://doi.org/10.1158/0008-5472.c.6508142
Autor:
Carol A. Lange, Tiffany N. Seagroves, Roland H. Wenger, David Hoogewijs, Alexandra Schörg, Brian J. Girard, Kristopher A. Lofgren, Gregory K. Hubbard, Andrea R. Daniel, Danielle L. Peacock, Tarah M. Regan Anderson
PDF file, 3449K, ChIP data showing recruitment of HIF-1a, HIF-2a, and RNA pol II to HREs 2-5 in the Brk promoter.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8aa4b0f832d37af15c8dc50e658ec6a
https://doi.org/10.1158/0008-5472.22397693
https://doi.org/10.1158/0008-5472.22397693
Autor:
Carol A. Lange, Tiffany N. Seagroves, Roland H. Wenger, David Hoogewijs, Alexandra Schörg, Brian J. Girard, Kristopher A. Lofgren, Gregory K. Hubbard, Andrea R. Daniel, Danielle L. Peacock, Tarah M. Regan Anderson
PDF file, 4524K, Regulation of Brk protein and mRNA expression in MCF7 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f3aa9d90d279136cd7974af8e170f92
https://doi.org/10.1158/0008-5472.22397696.v1
https://doi.org/10.1158/0008-5472.22397696.v1
Autor:
Carol A. Lange, Tiffany N. Seagroves, Roland H. Wenger, David Hoogewijs, Alexandra Schörg, Brian J. Girard, Kristopher A. Lofgren, Gregory K. Hubbard, Andrea R. Daniel, Danielle L. Peacock, Tarah M. Regan Anderson
PDF file, 5252K, Table detailing patient information from HCI tumor samples used.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58904ddb60ac2db037cbf308ea852792
https://doi.org/10.1158/0008-5472.22397684.v1
https://doi.org/10.1158/0008-5472.22397684.v1
Autor:
Carol A. Lange, Tiffany N. Seagroves, Roland H. Wenger, David Hoogewijs, Alexandra Schörg, Brian J. Girard, Kristopher A. Lofgren, Gregory K. Hubbard, Andrea R. Daniel, Danielle L. Peacock, Tarah M. Regan Anderson
PDF file, 2022K, Western and mRNA data downing retroviral transduction of Brk gene and subsequent over expression, as well as maintenance of HIF1a/2a knockdown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d8bef4faa8ba7f6c0bdee545c6ce8a5
https://doi.org/10.1158/0008-5472.22397690.v1
https://doi.org/10.1158/0008-5472.22397690.v1
Publikováno v:
Cancer Research. 83:562-562
The Epidermal Growth Factor Receptor ligand, Amphiregulin, is a key proliferative effector of estrogen receptor signaling in breast cancer and also plays a role in other malignancies. Amphiregulin is a single-pass transmembrane protein proteolyticall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af12a9a32157e0010ee32016e6119096
https://doi.org/10.1158/1538-7445.am2023-562
https://doi.org/10.1158/1538-7445.am2023-562
Publikováno v:
Antibody Therapeutics
Background The Epidermal Growth Factor Receptor (EGFR) ligand, Amphiregulin (AREG), is a key proliferative effector of estrogen receptor signaling in breast cancer and also plays a role in other malignancies. AREG is a single-pass transmembrane prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24c208f763b75e8c516510beda7951bf
http://europepmc.org/articles/PMC8643873
http://europepmc.org/articles/PMC8643873