Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kristoffer W. Balling"'
Autor:
Kristoffer W. Balling, Brian Lauritzen, Janne Olling, Mads Bjelke, Cecilia Augustsson, Ida Hilden, Anne Charlotte Hegelund, Kristin L. Abel
Publikováno v:
Journal of thrombosis and haemostasis : JTH. 17(3)
Essentials Hemophilia patients on concizumab prophylaxis may need rFVIIa to treat breakthrough bleeds. Effect and safety of concizumab + rFVIIa were tested in vitro and in vivo. Concizumab + rFVIIa had no additive effects on bleeding in hemophilic ra
Autor:
Berit Olsen Krogh, Brit B. Sørensen, L. Anders Svensson, Mirella Ezban, Kristoffer W. Balling, Jens Breinholt, Helle Heibroch Petersen, Jes Thorn Clausen, Lene Hansen, Christina Jespersgaard, Birgitte Friederichsen, Albrecht Gruhler, Andrew Neil Bowler, Brian Lauritzen, Lars Christian Petersen, Søren E. Bjørn, Thomas Egebjerg, Mette B. Hermit, Ida Hilden
Publikováno v:
Blood. 119:5871-5878
Hemophilia is treated by IV replacement therapy with Factor VIII (FVIII) or Factor IX (FIX), either on demand to resolve bleeding, or as prophylaxis. Improved treatment may be provided by drugs designed for subcutaneous and less frequent administrati
Autor:
Mirella Ezban, S. Segel, Thomas Dock Steenstrup, A. Bagger-Sørensen, Egon Persson, Stefan Lethagen, Niels Kristian Klausen, Ida Hilden, M. L. S. Christiansen, Dorthe Viuff, Brit B. Sørensen, Kristoffer W. Balling, Marianne Kjalke
Publikováno v:
Haemophilia. 16:878-887
The aim of this study was to evaluate the in vitro function of the new recombinant factor VIII (FVIII) compound, N8. The specific activity of N8 as measured in a FVIII:C one-stage clot assay was 9300±400 IU mg(-1) based on the analysis of seven indi
Autor:
Christina Jespersgaard, Flemming Möller, Torben Elm, Wendy Kappers, Mikael Tranholm, Bernd Peschke, Henning R. Stennicke, Hermann Pelzer, Ditte M. Karpf, Anne K. Kristensen, Ida Hilden, Mirella Ezban, Are Bogsnes, Heidi L. Holmberg, Egon Persson, Anette A. Pedersen, Peter B. Johansen, Henrik Rahbek-Nielsen, Lars Thim, Eva H. N. Olsen, Kristine Øvlisen, Frederik Rode, C. N. Gudme, Søren E. Bjørn, Kristoffer W. Balling, Marianne Kjalke
Publikováno v:
Blood. 121(11)
Frequent infusions of intravenous factor VIII (FVIII) are required to prevent bleeding associated with hemophilia A. To reduce the treatment burden, recombinant FVIII with a longer half-life was developed without changing the protein structure. FVIII
Autor:
Mette Dahl Andersen, Lars Christian Petersen, Brit B. Sørensen, Henrik Agersø, Henrik Østergaard, Thomas N. Krogh, Lene Hansen, Karin Knobe, Pernille Holm, Anette A. Pedersen, Mette B. Hermit, Kristoffer W. Balling, Torben Elm, Mikael Tranholm, Timothy C. Nichols, Flemming Möller, Jais Rose Bjelke, Jørn Meidahl Petersen, Mirella Ezban, Søren E. Bjørn, Marie Louise S. Christiansen, Haleh Ahmadian
Publikováno v:
Blood. 118(8)
Current management of hemophilia B entails multiple weekly infusions of factor IX (FIX) to prevent bleeding episodes. In an attempt to make a longer acting recombinant FIX (rFIX), we have explored a new releasable protraction concept using the native
Publikováno v:
Thrombosis and Haemostasis. 104:860-861
The D2194G mutation is responsible for increased levels of FV1 in carriers of the factor V R2 haplotype