Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Kristoffer T.G. Rigbolt"'
Autor:
Henrik H. Hansen, Johanna Perens, Urmas Roostalu, Jacob Lercke Skytte, Casper Gravesen Salinas, Pernille Barkholt, Ditte Dencker Thorbek, Kristoffer T.G. Rigbolt, Niels Vrang, Jacob Jelsing, Jacob Hecksher-Sørensen
Publikováno v:
Molecular Metabolism, Vol 47, Iss , Pp 101171- (2021)
Objective: The development of effective anti-obesity therapeutics relies heavily on the ability to target specific brain homeostatic and hedonic mechanisms controlling body weight. To obtain further insight into neurocircuits recruited by anti-obesit
Externí odkaz:
https://doaj.org/article/bd964deac5714ad4a7d015ebc7bd52eb
Autor:
Natasha C. Bergmann, Chen Zhang, Mikkel B. Christensen, Birgitte Holst, Christoffer A. Hagemann, Morten Hedegaard, Mechthilde Falkenhahn, Stefan Theis, Sebastian M. Nguyen Heimbürger, Henrik H. Hansen, Tina Jorsal, Niels Vrang, Filip K. Knop, Kristin Breitschopf, Tina Vilsbøll, Kristoffer T.G. Rigbolt, Jacob Jelsing, Stephanie Holm, Martin R. Madsen
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 106:e966-e981
Context The mechanisms underlying Roux-en-Y gastric bypass (RYGB) surgery-induced weight loss and the immediate postoperative beneficial metabolic effects associated with the operation remain uncertain. Enteroendocrine cell (EEC) secretory function h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5ef82b6a48a2ca3aa12fc4f656b064f
https://doi.org/10.1210/clinem/dgaa803
https://doi.org/10.1210/clinem/dgaa803
Autor:
Kristoffer T.G. Rigbolt, Frederik Helgstrand, Jens F. Rehfeld, Ebbe Langholz, Claus B. Juhl, Torben Østergaard, Niels Vrang, Chen Zhang, Brynjulf Mortensen, Philip J. Larsen, Marie M. Christensen, Erik Wandall, Mechthilde Falkenhahn, Frederik Sørensen, Stefan Theis, René Klinkby Støving, Julie Lyng Forman, Petra B. Musholt, Torsten Schmidt, Filip K. Knop, Thomas Rydborg, Tina Jorsal, Steffen U. Friis, Tina Vilsbøll, Alin R. Aldries, Jacob Jelsing, Andrea Karen Floyd, Eva B. Nygaard, Dorte Worm
Publikováno v:
Jorsal, T, Christensen, M M, Mortensen, B, Nygaard, E B, Zhang, C, Rigbolt, K, Wandall, E, Langholz, E, Friis, S, Worm, D, Floyd, A, Helgstrand, F, Støving, R K, Aldries, A R, Juhl, C B, Østergaard, T, Rydborg, T, Forman, J L, Sørensen, F, Schmidt, T, Falkenhahn, M, Musholt, P B, Theis, S, Larsen, P J, Rehfeld, J F, Vrang, N, Jelsing, J, Vilsbøll, T & Knop, F K 2020, ' Gut Mucosal Gene Expression and Metabolic Changes After Roux-en-Y Gastric Bypass Surgery ', Obesity, vol. 28, no. 11, pp. 2163-2174 . https://doi.org/10.1002/oby.22973
OBJECTIVE: Changes in the secretion of gut-derived peptide hormones have been associated with the metabolic benefits of Roux-en-Y gastric bypass (RYGB) surgery. In this study, the effects of RYGB on anthropometrics, postprandial plasma hormone respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd8729e918cb8f82b6c6852066cbdc2
https://doi.org/10.1002/oby.22973
https://doi.org/10.1002/oby.22973
Autor:
Tina Vilsbøll, Malte P. Suppli, Charlotte Strandberg, Jill Levin Langhoff, Nicolai J. Wewer Albrechtsen, Gerrit van Hall, Filip K. Knop, Asger Lund, Jens J. Holst, Mia Demant, Merete J Kønig, Jonatan I. Bagger, Kristoffer T.G. Rigbolt
Publikováno v:
Diabetes. 69:1090-1099
Glucagon secretion is regulated by circulating glucose, but it has turned out that amino acids also play an important role and that hepatic amino acid metabolism and glucagon are linked in a mutual feedback cycle, the liver–α-cell axis. On the bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a8a92a552db05d9def69ee16d00a7bb
https://doi.org/10.2337/db19-0715
https://doi.org/10.2337/db19-0715
Autor:
Niels Vrang, Michele Puglia, Tune H. Pers, Birgitte Rahbek Kornum, Michael Feigh, Helene M Ægidius, Jacob Jelsing, Philip Hallenborg, Sanne Skovgård Veidal, Blagoy Blagoev, Kristoffer T.G. Rigbolt
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Ægidius, H M, Veidal, S S, Feigh, M, Hallenborg, P, Puglia, M, Pers, T H, Vrang, N, Jelsing, J, Kornum, B R, Blagoev, B & Rigbolt, K T G 2020, ' Multi-omics characterization of a diet-induced obese model of non-alcoholic steatohepatitis ', Scientific Reports, vol. 10, no. 1, 1148 . https://doi.org/10.1038/s41598-020-58059-7
Scientific Reports
Ægidius, H M, Veidal, S S, Feigh, M, Hallenborg, P, Puglia, M, Pers, T H, Vrang, N, Jelsing, J, Kornum, B R, Blagoev, B & Rigbolt, K T G 2020, ' Multi-omics characterization of a diet-induced obese model of non-alcoholic steatohepatitis ', Scientific Reports, vol. 10, no. 1, 1148 . https://doi.org/10.1038/s41598-020-58059-7
Scientific Reports
To improve the understanding of the complex biological processes underlying the development of non-alcoholic steatohepatitis (NASH), a multi-omics approach combining bulk RNA-sequencing based transcriptomics, quantitative proteomics and single-cell R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07c55c07b520910373ed7da73108ed82
http://link.springer.com/article/10.1038/s41598-020-58059-7
http://link.springer.com/article/10.1038/s41598-020-58059-7
Autor:
Annemarie Aarup, Bo Feldt-Rasmussen, Helene M Ægidius, Thomas Secher, Lisbeth Nielsen Fink, Frederikke E. Sembach, Jens Nielsen, Niels Vrang, Jacob Jelsing, Kristoffer T.G. Rigbolt, Mette V. Østergaard
Publikováno v:
Sembach, F E, Agidius, H M, Fink, L N, Secher, T, Aarup, A, Jelsing, J, Vrang, N, Feldt-Rasmussen, B, Rigbolt, K T G, Nielsen, J C & Østergaard, M V 2021, ' Integrative transcriptomic profiling of a mouse model of hypertension-accelerated diabetic kidney disease ', DMM Disease Models and Mechanisms, vol. 14, no. 10, dmm049086 . https://doi.org/10.1242/dmm.049086
Disease Models & Mechanisms, Vol 14, Iss 10 (2021)
Disease Models & Mechanisms
article-version (VoR) Version of Record
Disease Models & Mechanisms, Vol 14, Iss 10 (2021)
Disease Models & Mechanisms
article-version (VoR) Version of Record
The current understanding of molecular mechanisms driving diabetic kidney disease (DKD) is limited, partly due to the complex structure of the kidney. To identify genes and signalling pathways involved in the progression of DKD, we compared kidney co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74ba84935ffe3e2e8964eb58d8e8bba4
https://doi.org/10.1242/dmm.049086
https://doi.org/10.1242/dmm.049086
Autor:
Urmas Roostalu, Kristoffer T.G. Rigbolt, Casper Gravesen Salinas, Johanna Perens, Niels Vrang, Pernille Barkholt, Jacob Lercke Skytte, Ditte Dencker Thorbek, Jacob Hecksher-Sørensen, Henrik H. Hansen, Jacob Jelsing
Publikováno v:
Hansen, H H, Perens, J, Roostalu, U, Skytte, J L, Salinas, C B G, Barkholt, P, Thorbek, D D, Rigbolt, K T G, Vrang, N, Jelsing, J & Hecksher-Sørensen, J 2021, ' Whole-brain activation signatures of weightlowering drugs ', Molecular Metabolism, vol. 47, 101171 . https://doi.org/10.1016/j.molmet.2021.101171
Molecular Metabolism, Vol 47, Iss, Pp 101171-(2021)
Molecular Metabolism
Molecular Metabolism, Vol 47, Iss, Pp 101171-(2021)
Molecular Metabolism
Objective The development of effective anti-obesity therapeutics relies heavily on the ability to target specific brain homeostatic and hedonic mechanisms controlling body weight. To obtain further insight into neurocircuits recruited by anti-obesity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8024f93f404dc470a060e22639291c38
https://orbit.dtu.dk/en/publications/b3ee5cba-b147-4bb0-b632-6506b3a611a7
https://orbit.dtu.dk/en/publications/b3ee5cba-b147-4bb0-b632-6506b3a611a7
Autor:
Mette Simone Aae Madsen, Niels Vrang, Kristoffer T.G. Rigbolt, Martin Tue Mikkelsen, Rikke Veggerby Grønlund, Henrik H. Hansen, John Eid, Martin R. Madsen, Jacob Jelsing, Mikkel Christensen-Dalsgaard, Morten Otto Alexander Sommer
Publikováno v:
Madsen, M S A, Grønlund, R V, Eid, J, Christensen-Dalsgaard, M, Sommer, M O A, Rigbolt, K, Madsen, M R, Jelsing, J, Vrang, N, Hansen, H H & Mikkelsen, M T 2021, ' Characterization of local gut microbiome and intestinal transcriptome responses to rosiglitazone treatment in diabetic db/db mice ', Biomedicine and Pharmacotherapy, vol. 133, 110966 . https://doi.org/10.1016/j.biopha.2020.110966
Biomedicine & Pharmacotherapy, Vol 133, Iss, Pp 110966-(2021)
Biomedicine & Pharmacotherapy, Vol 133, Iss, Pp 110966-(2021)
The gut microbiota has been implicated in the therapeutic effects of antidiabetics. It is unclear if antidiabetics directly influences gut microbiome-host interaction. Oral peroxisome proliferator-activated receptor-γ (PPAR-γ) agonists, such as ros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85f2e00c6d1ca24a3497296877eebe2d
https://orbit.dtu.dk/en/publications/c7ed2afc-ed03-48cc-bf2f-189dd40a0a6b
https://orbit.dtu.dk/en/publications/c7ed2afc-ed03-48cc-bf2f-189dd40a0a6b
Autor:
Marisa Fernández Cachón, Chen Zhang, Thorsten Schmidt, Lise Christine Biehl Rudkjær, Kristoffer T.G. Rigbolt, Stefan Theis, Jacob Jelsing, Niels Vrang, Mechthilde Falkenhahn
Publikováno v:
Peptides. 136
Roux-en-Y gastric bypass (RYGB) is the most efficient intervention in morbid obesity and promotes metabolic improvements in several peripheral tissues. However, the underlying molecular mechanisms are still poorly understood. To further understand th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::723bf2110bc4774fc9392516e5a8259c
https://pubmed.ncbi.nlm.nih.gov/33253774
https://pubmed.ncbi.nlm.nih.gov/33253774
Autor:
Sidsel Støy, Kristoffer T.G. Rigbolt, Ewa Terczyńska-Dyla, Tea Lund Laursen, Nils E. Magnusson, Stephen Hamilton-Dutoit, Oliviero Riggio, Peter Lykke Eriksen, Bent Deleuran, Emilie Glavind, Frank Viborg Mortensen, Hendrik Vilstrup, Thomas Damgaard Sandahl, Sanne Skovgård Veidal
Publikováno v:
Støy, S, Laursen, T L, Glavind, E, Eriksen, P L, Terczynska-Dyla, E, Magnusson, N E, Hamilton-Dutoit, S, Mortensen, F V, Veidal, S S, Rigbolt, K, Riggio, O, Deleuran, B, Vilstrup, H & Sandahl, T D 2020, ' Low Interleukin-22 Binding Protein Is Associated With High Mortality in Alcoholic Hepatitis and Modulates Interleukin-22 Receptor Expression ', Clinical and Translational Gastroenterology, vol. 11, no. 8, pp. e00197 . https://doi.org/10.14309/ctg.0000000000000197
Clinical and Translational Gastroenterology
Clinical and Translational Gastroenterology
INTRODUCTION: In alcoholic hepatitis (AH), high interleukin (IL)-22 production is associated with disease improvement, purportedly through enhanced infection resistance and liver regeneration. IL-22 binding protein (BP) binds and antagonizes IL-22 bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d02deea55881ce21583f99430ae1d0c4
https://pure.au.dk/portal/da/publications/low-interleukin22-binding-protein-is-associated-with-high-mortality-in-alcoholic-hepatitis-and-modulates-interleukin22-receptor-expression(63d7c73b-cf24-4a59-b539-230381f4f3ad).html
https://pure.au.dk/portal/da/publications/low-interleukin22-binding-protein-is-associated-with-high-mortality-in-alcoholic-hepatitis-and-modulates-interleukin22-receptor-expression(63d7c73b-cf24-4a59-b539-230381f4f3ad).html