Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Kristoffer Svensson"'
Autor:
Vitor F. Martins, Samuel A. LaBarge, Alexandra Stanley, Kristoffer Svensson, Chao-Wei Hung, Omer Keinan, Theodore P. Ciaraldi, Dion Banoian, Ji E. Park, Christina Ha, Byron Hetrick, Gretchen A. Meyer, Andrew Philp, Larry L. David, Robert R. Henry, Joseph E. Aslan, Alan R. Saltiel, Carrie. E. McCurdy, Simon Schenk
Publikováno v:
JCI Insight, Vol 7, Iss 1 (2022)
While current thinking posits that insulin signaling to glucose transporter 4 (GLUT4) exocytic translocation and glucose uptake in skeletal muscle and adipocytes is controlled by phosphorylation-based signaling, many proteins in this pathway are acet
Externí odkaz:
https://doaj.org/article/18e5e8b48d3742ed866a0d0874f38390
Autor:
Kristoffer Svensson, Samuel A. LaBarge, Abha Sathe, Vitor F. Martins, Shahriar Tahvilian, Jennifer M. Cunliffe, Roman Sasik, Sushil K. Mahata, Gretchen A. Meyer, Andrew Philp, Larry L. David, Samuel R. Ward, Carrie E. McCurdy, Joseph E. Aslan, Simon Schenk
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 11, Iss 2, Pp 464-477 (2020)
Abstract Background Reversible ε‐amino acetylation of lysine residues regulates transcription as well as metabolic flux; however, roles for specific lysine acetyltransferases in skeletal muscle physiology and function are unknown. In this study, w
Externí odkaz:
https://doaj.org/article/19b284faa0d3446e92f314afabd7c769
Autor:
Jessica R. Dent, Vitor F. Martins, Kristoffer Svensson, Samuel A. LaBarge, Noah C. Schlenk, Mary C. Esparza, Elisa H. Buckner, Gretchen A. Meyer, D. Lee. Hamilton, Simon Schenk, Andrew Philp
Publikováno v:
Molecular Metabolism, Vol 6, Iss 12, Pp 1574-1584 (2017)
Objective: Lysine acetylation is an important post-translational modification that regulates metabolic function in skeletal muscle. The acetyltransferase, general control of amino acid synthesis 5 (GCN5), has been proposed as a regulator of mitochond
Externí odkaz:
https://doaj.org/article/b91759533ac34447a832516cf0bc2b57
Autor:
Vitor F. Martins, Shahriar Tahvilian, Ji H. Kang, Kristoffer Svensson, Byron Hetrick, Wallace S. Chick, Simon Schenk, Carrie E. McCurdy
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Introduction: The Phosphoinositide 3-kinase (PI3K) signaling pathway plays an important role in skeletal muscle insulin-stimulated glucose uptake. While whole-body and tissue specific knockout (KO) of individual or combinations of the regulatory subu
Externí odkaz:
https://doaj.org/article/351c4fc78ac246cf92cc52962d9faab1
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0158716 (2016)
The kidney has a high energy demand and is dependent on oxidative metabolism for ATP production. Accordingly, the kidney is rich in mitochondria, and mitochondrial dysfunction is a common denominator for several renal diseases. While the mitochondria
Externí odkaz:
https://doaj.org/article/4737aa39bbd247afaf2ef4fd02543117
Autor:
Henrik Andersson, Blanka Andersson, Daniel Eklund, Eyler Ngoh, Alexander Persson, Kristoffer Svensson, Maria Lerm, Robert Blomgran, Olle Stendahl
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101514 (2014)
Macrophages in the lung are the primary cells being infected by Mycobacterium tuberculosis (Mtb) during the initial manifestation of tuberculosis. Since the adaptive immune response to Mtb is delayed, innate immune cells such as macrophages and neutr
Externí odkaz:
https://doaj.org/article/d3de8f92fbdd4dc6bf2c789d460f6aaa
Autor:
Byron Hetrick, Alexandra Stanley, Vitor F. Martins, Carrie E. McCurdy, Theodore P. Ciaraldi, Ji E. Park, Samuel LaBarge, Christina Ha, Larry L. David, Andrew Philp, Robert R. Henry, Gretchen A. Meyer, Dion Banoian, Omer Keinan, Joseph E. Aslan, Simon Schenk, Chao-Wei Hung, Kristoffer Svensson, Alan R. Saltiel
Publikováno v:
JCI Insight
JCI insight, vol 7, iss 1
JCI insight, vol 7, iss 1
While current thinking posits that insulin signaling to glucose transporter 4 (GLUT4) exocytic translocation and glucose uptake in skeletal muscle and adipocytes is controlled by phosphorylation-based signaling, many proteins in this pathway are acet
Autor:
Roman Sasik, Simon Schenk, Abha Sathe, Samuel LaBarge, Samuel R. Ward, Carrie E. McCurdy, Jennifer M. Cunliffe, Gretchen A. Meyer, Joseph E. Aslan, Shahriar Tahvilian, Kristoffer Svensson, Larry L. David, Andrew Philp, Sushil K. Mahata, Vitor F. Martins
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle
Journal of Cachexia, Sarcopenia and Muscle, Vol 11, Iss 2, Pp 464-477 (2020)
Journal of Cachexia, Sarcopenia and Muscle, Vol 11, Iss 2, Pp 464-477 (2020)
Background Reversible ε‐amino acetylation of lysine residues regulates transcription as well as metabolic flux; however, roles for specific lysine acetyltransferases in skeletal muscle physiology and function are unknown. In this study, we investi
Autor:
Carrie E. McCurdy, Ji Park, Shivani Lakkaraju, Simon Schenk, Byron Hetrick, Kristoffer Svensson, Maedha Begur, Vitor F. Martins
Publikováno v:
Am J Physiol Cell Physiol
Whether the histone deacetylase (HDAC) and sirtuin families of protein deacetylases regulate insulin-stimulated glucose uptake, independent of their transcriptional effects, has not been studied. Our objective was to determine the nontranscriptional
Autor:
Theodore P. Ciaraldi, Carrie E. McCurdy, Andrew Philp, Robert R. Henry, Gretchen A. Meyer, Dion Banoian, Joseph E. Aslan, Samuel LaBarge, Jennifer M. Cunliffe, Vitor F. Martins, Byron Hetrick, Larry L. David, Kristoffer Svensson, Simon Schenk
Publikováno v:
Journal of the Endocrine Society
Introduction: Akt is a critical mediator of insulin-stimulated glucose uptake in skeletal muscle. The acetyltransferases, E1A binding protein p300 (p300) and cAMP response element-binding protein binding protein (CBP) are phosphorylated and activated