Výsledky vyhledávání - "Kristoffer Søberg"

Akademický článek

A novel homozygous variant in the SPG7 gene presenting with childhood optic nerve atrophy

Autor: Kathrine O. Eriksen, Andreas Reidar Wigers, Iselin Marie Wedding, Anne Kjersti Erichsen, Tuva Barøy, Kristoffer Søberg, Øystein Kalsnes Jørstad

Publikováno v: American Journal of Ophthalmology Case Reports, Vol 26, Iss , Pp 101400- (2022)

Purpose: To describe a case of hereditary spastic ataxia (HSP) presenting with childhood optic nerve atrophy and report a novel homozygous variant in the SPG7 gene. Observations: A 57-year-old man suffering from progressive optic nerve atrophy since

Externí odkaz: https://doaj.org/article/16d5c2b889a649b185a6450f0c691660

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Akademický článek

The Molecular Basis for Specificity at the Level of the Protein Kinase a Catalytic Subunit

Autor: Kristoffer Søberg, Bjørn Steen Skålhegg

Publikováno v: Frontiers in Endocrinology, Vol 9 (2018)

Assembly of multi enzyme complexes at subcellular localizations by anchoring- and scaffolding proteins represents a pivotal mechanism for achieving spatiotemporal regulation of cellular signaling after hormone receptor targeting [for review, see (1)]

Externí odkaz: https://doaj.org/article/f93f87f01a1344afa67653ee3dc6656a

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Akademický článek

Evolution of the cAMP-dependent protein kinase (PKA) catalytic subunit isoforms.

Autor: Kristoffer Søberg, Line Victoria Moen, Bjørn Steen Skålhegg, Jon Kristen Laerdahl

Publikováno v: PLoS ONE, Vol 12, Iss 7, p e0181091 (2017)

The 3',5'-cyclic adenosine monophosphate (cAMP)-dependent protein kinase, or protein kinase A (PKA), pathway is one of the most versatile and best studied signaling pathways in eukaryotic cells. The two paralogous PKA catalytic subunits Cα and Cβ,

Externí odkaz: https://doaj.org/article/0a550220421c4cb3b5f6bb7613987ac6

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Akademický článek

Evolutionary paths of the cAMP-dependent protein kinase (PKA) catalytic subunits.

Autor: Kristoffer Søberg, Tore Jahnsen, Torbjørn Rognes, Bjørn S Skålhegg, Jon K Laerdahl

Publikováno v: PLoS ONE, Vol 8, Iss 4, p e60935 (2013)

3',5'-cyclic adenosine monophosphate (cAMP) dependent protein kinase or protein kinase A (PKA) has served as a prototype for the large family of protein kinases that are crucially important for signal transduction in eukaryotic cells. The PKA catalyt

Externí odkaz: https://doaj.org/article/93ae8b053e6f4790a66e27c91ff52310

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Akademický článek

Identification and characterization of novel mutations in the human gene encoding the catalytic subunit Calpha of protein kinase A (PKA).

Autor: Kristoffer Søberg, Anja C V Larsen, Mandy Diskar, Paul H Backe, Magnar Bjørås, Tore Jahnsen, Jon K Laerdahl, Torbjørn Rognes, Friedrich W Herberg, Bjørn S Skålhegg

Publikováno v: PLoS ONE, Vol 7, Iss 4, p e34838 (2012)

The genes PRKACA and PRKACB encode the principal catalytic (C) subunits of protein kinase A (PKA) Cα and Cβ, respectively. Cα is expressed in all eukaryotic tissues examined and studies of Cα knockout mice demonstrate a crucial role for Cα in no

Externí odkaz: https://doaj.org/article/fc3a73b0237548fa9be1beb718b66b04

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PKA Cβ: a forgotten catalytic subunit of cAMP-dependent protein kinase opens new windows for PKA signaling and disease pathologies

Autor: Bjørn Steen Skålhegg, Susan S. Taylor, Lily Vu, Maximilian Wallbott, Jian Wu, Jessica G.H. Bruystens, Friedrich W. Herberg, Erik M F Machal, Blaine Baker, Kristoffer Søberg, Elimelda Moige Ongeri, Francesco Raimondi, Faihaa Ahmed

Publikováno v: Biochemical Journal. 478:2101-2119

3′,5′-cyclic adenosine monophosphate (cAMP) dependent protein kinase or protein kinase A (PKA) has served as a prototype for the large family of protein kinases that are crucially important for signal transduction in eukaryotic cells. The PKA cat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eaa8b0037ae445a37c267eda66d661a
https://doi.org/10.1042/bcj20200867

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The Tails of Protein Kinase A

Autor: Jian Wu, Sabine Pautz, Bjørn Steen Skålhegg, Friedrich W. Herberg, Evan K. Kobori, Kristoffer Søberg, Susan S. Taylor

Publikováno v: Molecular pharmacology, vol 101, iss 4
Mol Pharmacol

Protein kinase A (PKA) is a holoenzyme consisting of a regulatory (R)-subunit dimer and two catalytic (C)-subunits. There are two major families of C-subunits, Cα and Cβ, and four functionally nonredundant R-subunits (RIα, RIβ, RIIα, RIIβ). In

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24d9baae224a1d1d8853ecc1b65e3af2
https://escholarship.org/uc/item/1mx7d9d7

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Evolutionary paths of the cAMP-dependent protein kinase (PKA) catalytic subunits

Autor: Jon K. Laerdahl, Bjørn Steen Skålhegg, Tore Jahnsen, Kristoffer Søberg, Torbjørn Rognes

Publikováno v: PLoS ONE, Vol 8, Iss 4, p e60935 (2013)
PLoS ONE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9e4592683e6686d0de1e7357a7d0e0a
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23593352/pdf/?tool=EBI

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Identification and characterization of novel mutations in the human gene encoding the catalytic subunit Calpha of protein kinase A (PKA)

Autor: Mandy Diskar, Jon K. Laerdahl, Anja C. V. Larsen, Torbjørn Rognes, Friedrich W. Herberg, Paul Hoff Backe, Kristoffer Søberg, Bjørn Steen Skålhegg, Magnar Bjørås, Tore Jahnsen

Publikováno v: PLoS ONE
PLoS ONE, Vol 7, Iss 4, p e34838 (2012)
PLoS ONE; Vol 7

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e119167941cee19d0f6f3476d7fa8408
https://pubmed.ncbi.nlm.nih.gov/22514673

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