Výsledky vyhledávání - "Kristoffer Berg‐Hansen"

Akademický článek

Lactate infusion elevates cardiac output through increased heart rate and decreased vascular resistance: a randomised, blinded, crossover trial in a healthy porcine model

Autor: Oskar Kjærgaard Hørsdal, Niels Moeslund, Kristoffer Berg-Hansen, Roni Nielsen, Niels Møller, Hans Eiskjær, Henrik Wiggers, Nigopan Gopalasingam

Publikováno v: Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-14 (2024)

Abstract Background Lactate is traditionally recognized as a by-product of anaerobic metabolism. However, lactate is a preferred oxidative substrate for stressed myocardium. Exogenous lactate infusion increases cardiac output (CO). The exact mechanis

Externí odkaz: https://doaj.org/article/65a963583d804b29bade278454b76dc0

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Akademický článek

Enantiomer‐Specific Cardiovascular Effects of the Ketone Body 3‐Hydroxybutyrate

Autor: Nigopan Gopalasingam, Niels Moeslund, Kristian Hylleberg Christensen, Kristoffer Berg‐Hansen, Jacob Seefeldt, Casper Homilius, Erik Nguyen Nielsen, Mie Ringgaard Dollerup, Aage K. Alstrup Olsen, Mogens Johannsen, Ebbe Boedtkjer, Niels Møller, Hans Eiskjær, Lars Christian Gormsen, Roni Nielsen, Henrik Wiggers

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 8 (2024)

Background The ketone body 3‐hydroxybutyrate (3‐OHB) increases cardiac output (CO) by 35% to 40% in healthy people and people with heart failure. The mechanisms underlying the effects of 3‐OHB on myocardial contractility and loading conditions

Externí odkaz: https://doaj.org/article/5b06f1a0c49843c0ad0ad5a5885374ac

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Akademický článek

Stimulation of the Hydroxycarboxylic Acid Receptor 2 With the Ketone Body 3‐Hydroxybutyrate and Niacin in Patients With Chronic Heart Failure: Hemodynamic and Metabolic Effects

Autor: Nigopan Gopalasingam, Kristian Hylleberg Christensen, Kristoffer Berg Hansen, Roni Nielsen, Mogens Johannsen, Lars Christian Gormsen, Ebbe Boedtkjer, Rikke Nørregaard, Niels Møller, Henrik Wiggers

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 12 (2023)

Background The ketone body 3‐hydroxybutyrate (3‐OHB) increases cardiac output (CO) in patients with heart failure through unknown mechanisms. 3‐OHB activates the hydroxycarboxylic acid receptor 2 (HCA2), which increases prostaglandins and suppr

Externí odkaz: https://doaj.org/article/d7894fbb62064170acc8b0e3d4e8cc34

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Akademický článek

Hemodynamic Effects of Ketone Bodies in Patients With Pulmonary Hypertension

Autor: Roni Nielsen, Kristian Hylleberg Christensen, Nigopan Gopalasingam, Kristoffer Berg‐Hansen, Jacob Seefeldt, Casper Homilius, Ebbe Boedtkjer, Mads Jønsson Andersen, Henrik Wiggers, Niels Møller, Hans Erik Bøtker, Søren Mellemkjær

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 10 (2023)

Background Pulmonary arterial hypertension (PAH) or chronic thromboembolic pulmonary hypertension (CTEPH) are debilitating diseases with a high mortality. Despite emerging treatments, pulmonary vascular resistance frequently remains elevated. However

Externí odkaz: https://doaj.org/article/b887476f157846f885d0464c1fbb0322

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Prolonged Cardiogenic Shock Due to Hydrogen Sulfide Intoxication Requiring Long-Term Venoarterial Extracorporeal Membrane Support

Autor: Kristoffer Berg Hansen, Steffen Christensen, Thomas Birkelund, Frederik Dalgaard, Henrik Wiggers

Publikováno v: Berg Hansen, K, Christensen, S, Birkelund, T, Dalgaard, F & Wiggers, H 2022, ' Prolonged Cardiogenic Shock Due to Hydrogen Sulfide Intoxication Requiring Long-Term Venoarterial Extracorporeal Membrane Support ', JACC: Case Reports, vol. 4, no. 21, pp. 1389-1393 . https://doi.org/10.1016/j.jaccas.2022.05.035

We describe a case of severe biventricular failure and cardiovascular collapse following exposure to the manure gas hydrogen sulfide. Initial tests indicated uncoupling of cellular bioenergetics in addition to myocardial damage. Cardiopulmonary suppo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16f2e6f4fe4124b2a293c4cee2d9b464
https://doi.org/10.1016/j.jaccas.2022.05.035

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The haemodynamic effects of phenylephrine after cardiac surgery

Autor: Peter Juhl‐Olsen, Kristoffer Berg‐Hansen, Jesper Nørskov, Johannes Enevoldsen, Johan Lyngklip Hermansen

Publikováno v: Juhl-Olsen, P, Berg-Hansen, K, Nørskov, J, Enevoldsen, J & Hermansen, J L 2023, ' The haemodynamic effects of phenylephrine after cardiac surgery ', Acta Anaesthesiologica Scandinavica . https://doi.org/10.1111/aas.14256

Background: Phenylephrine increases systemic- and pulmonary resistances and therefore may increase blood pressures at the expense of blood flow. Cardio-pulmonary bypass alters vasoreactivity and many patients exhibit chronotropic insufficiency after

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57d7ddb469bfc39b621846252e707f84
https://pure.au.dk/portal/da/publications/the-haemodynamic-effects-of-phenylephrine-after-cardiac-surgery(56667f51-3cab-4988-a858-ee49df39521d).html