Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Kristoffer, Brännström"'
Autor:
Jeanna A. Bugaytsova, Kristof Moonens, Artem Piddubnyi, Alexej Schmidt, Johan Olofsson Edlund, Gennadii Lisiutin, Kristoffer Brännström, Yevgen A. Chernov, Kaisa Thorel, Iryna Tkachenko, Oleksandra Sharova, Iryna Vikhrova, Anna Butsyk, Pavlo Shubin, Ruslana Chyzhma, Daniel X. Johansson, Harold Marcotte, Rolf Sjöström, Anna Shevtsova, Göran Bylund, Lena Rakhimova, Anders Lundquist, Oleksandra Berhilevych, Victoria Kasianchuk, Andrii Loboda, Volodymyr Ivanytsia, Kjell Hultenby, Mats A. A. Persson, Joana Gomes, Rita Matos, Fátima Gartner, Celso A. Reis, Jeannette M. Whitmire, D. Scott Merrell, Qiang Pan-Hammarström, Maréne Landström, Stefan Oscarson, Mario M. D’Elios, Lars Agreus, Jukka Ronkainen, Pertti Aro, Lars Engstrand, David Y. Graham, Vladyslava Kachkovska, Asish Mukhopadhyay, Sujit Chaudhuri, Bipul Chandra Karmakar, Sangita Paul, Oleksandr Kravets, Margarita Camorlinga, Javier Torres, Douglas E. Berg, Roman Moskalenko, Rainer Haas, Han Remaut, Lennart Hammarström, Thomas Borén
Publikováno v:
bioRxiv
SUMMARYThe majority of the world population carry the gastric pathogenHelicobacter pylori. Fortunately, most individuals experience only low-grade or no symptoms, but in many cases the chronic inflammatory infection develops into severe gastric disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb75ccea9610e2bc8aa31050d4df2219
https://europepmc.org/articles/PMC10245814/
https://europepmc.org/articles/PMC10245814/
Autor:
Irina Iakovleva, Afshan Begum, Kristoffer Brännström, Alexandra Wijsekera, Lina Nilsson, Jin Zhang, Patrik L Andersson, A Elisabeth Sauer-Eriksson, Anders Olofsson
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153529 (2016)
Amyloid formation of the human plasma protein transthyretin (TTR) is associated with several human disorders, including familial amyloidotic polyneuropathy (FAP) and senile systemic amyloidosis. Dissociation of TTR's native tetrameric assembly is the
Externí odkaz:
https://doaj.org/article/be964ba9eb594e44af1bf6f2ec6ee692
Autor:
Lina Nilsson, Andreas Larsson, Afshan Begum, Irina Iakovleva, Marcus Carlsson, Kristoffer Brännström, A Elisabeth Sauer-Eriksson, Anders Olofsson
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153112 (2016)
Amyloid formation of the plasma protein transthyretin (TTR) has been linked to familial amyloid polyneuropathy and senile systemic amyloidosis. Binding of ligands within its natural hormone binding site can stabilize the tetrameric structure and impa
Externí odkaz:
https://doaj.org/article/e3019fef752740b882150fe0af0e72b1
Autor:
Pardeep Singh, Christian Bartens, Anders Olofsson, Kristoffer Brännström, Dan E. Adolfsson, Andrew G. Cairns, Jörgen Ådén, Fredrik Almqvist
Publikováno v:
The Journal of Organic Chemistry. 84:3887-3903
We here describe the use of three-component reactions to synthesize tricyclic pyridine ring-fused 2-pyridones. The developed protocols have a wide substrate scope and allow for the installation of ...
Autor:
Anna Åberg, Pär Gideonsson, Anna Vallström, Annelie Olofsson, Carina Öhman, Lena Rakhimova, Thomas Borén, Lars Engstrand, Kristoffer Brännström, Anna Arnqvist
Publikováno v:
PLoS Pathogens, Vol 10, Iss 7, p e1004234 (2014)
During persistent infection, optimal expression of bacterial factors is required to match the ever-changing host environment. The gastric pathogen Helicobacter pylori has a large set of simple sequence repeats (SSR), which constitute contingency loci
Externí odkaz:
https://doaj.org/article/c288db2fb0d34e3bb3457ae314427a9d
Autor:
Kristoffer Brännström, Malin Lindhagen-Persson, Anna L Gharibyan, Irina Iakovleva, Monika Vestling, Mikael E Sellin, Thomas Brännström, Ludmilla Morozova-Roche, Lars Forsgren, Anders Olofsson
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90857 (2014)
Antibodies that preferentially and specifically target pathological oligomeric protein and peptide assemblies, as opposed to their monomeric and amyloid counterparts, provide therapeutic and diagnostic opportunities for protein misfolding diseases. U
Externí odkaz:
https://doaj.org/article/85bdb2aa8c704054b936e00b43b5987b
Autor:
Ximena Aguilar, Jeanette Blomberg, Kristoffer Brännström, Anders Olofsson, Jürgen Schleucher, Stefan Björklund
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e98575 (2014)
Mediator is an evolutionary conserved multi-protein complex present in all eukaryotes. It functions as a transcriptional co-regulator by conveying signals from activators and repressors to the RNA polymerase II transcription machinery. The Arabidopsi
Externí odkaz:
https://doaj.org/article/c92256c2113749e6945893ab82e483c9
Autor:
Jafar Mahdavi, Pierre-Joseph Royer, Hong S. Sjölinder, Sheyda Azimi, Tim Self, Jeroen Stoof, Lee M. Wheldon, Kristoffer Brännström, Raymond Wilson, Joanna Moreton, James W. B. Moir, Carina Sihlbom, Thomas Borén, Ann-Beth Jonsson, Panos Soultanas, Dlawer A. A. Ala'Aldeen
Publikováno v:
Open Biology, Vol 3, Iss 10 (2013)
Interactions between commensal pathogens and hosts are critical for disease development but the underlying mechanisms for switching between the commensal and virulent states are unknown. We show that the human pathogen Neisseria meningitidis, the lea
Externí odkaz:
https://doaj.org/article/0922dc73be34404db1e8d80e0eb1dffe
Autor:
Marcus Wallgren, Martin Lidman, Anders Pedersen, Kristoffer Brännström, B Göran Karlsson, Gerhard Gröbner
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61452 (2013)
The anti-apoptotic B-cell CLL/lymphoma-2 (Bcl-2) protein and its counterpart, the pro-apoptotic Bcl-2-associated X protein (Bax), are key players in the regulation of the mitochondrial pathway of apoptosis. However, how they interact at the mitochond
Externí odkaz:
https://doaj.org/article/80da6c0cb0e34a3aa4be47a1b16738a6
Autor:
Rajendra Kumar, Kazutoshi Kasho, Ikenna Obi, Kristoffer Brännström, Rabindra Nath Das, Parham L. Pourbozorgi, James E. Mason, Jan Jamroskovic, Nasim Sabouri, Mattias Hedenström, Mara Doimo, Sjoerd Wanrooij, Sebastian Sulis Sato, Marco Deiana, Erik Chorell, Almaz Akhunzianov, Paolo Medini, Daniel Öhlund, Karam Chand
Publikováno v:
Journal of the American Chemical Society
The signal transducer and activator of transcription 3 (STAT3) protein is a master regulator of most key hallmarks and enablers of cancer, including cell proliferation and the response to DNA damage. G-Quadruplex (G4) structures are four-stranded non