Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Kristofer D. Sinclair"'
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0118696 (2015)
Nearly 1.3 million total joint replacement procedures are performed in the United States annually, with numbers projected to rise exponentially in the coming decades. Although finite infection rates for these procedures remain consistently low, devic
Externí odkaz:
https://doaj.org/article/a350d043a1e6473389a3a9ec26812757
Publikováno v:
European Cells & Materials, Vol 37, Pp 265-276 (2019)
Periprosthetic infection in total knee arthroplasty is a difficult-to-treat complication. Current implant revision procedures use non-degradable, antibiotic-loaded bone cement for local antimicrobial delivery. As a permanent foreign body, antibiotic-
Autor:
Benjamin D. Brooks, Amanda E. Brooks, Alex G. Williams, Brittany Coats, Sherry N. Davidoff, David W. Grainger, Scott T. Lawson, Kristofer D. Sinclair
Publikováno v:
Journal of Biomedical Materials Research Part B: Applied Biomaterials. 102:1074-1083
Infection remains a significant problem associated with biomedical implants and orthopedic surgeries, especially in revision total joint replacements. Recent advances in antibiotic-releasing bone void fillers (BVF) provide new opportunities to addres
Autor:
John G. Skedros, Ryan W. Farnsworth, Alex N. Knight, Roy D. Bloebaum, Kristofer D. Sinclair, Theresa X. Pham
Publikováno v:
Journal of Human Evolution. 64:366-379
For over a century, the arched trabecular patterns of the human proximal femur have been considered to resemble tension and compression stress trajectories produced by stereotypical bending loads. This reflects conventional modeling of the human femo
Autor:
Catherine Loc-Carrillo, Theresa X. Pham, Roy D. Bloebaum, Dustin L. Williams, Ryan W. Farnsworth, Kristofer D. Sinclair
Publikováno v:
Journal of Biomedical Materials Research Part B: Applied Biomaterials. 101:1143-1153
Antibiotic resistant bacterial infections are a growing problem in patient care. These infections are difficult to treat and severely affect the patient's quality of life. The goal of this translational experiment was to investigate the antimicrobial
Publikováno v:
Journal of Biomedical Materials Research Part B: Applied Biomaterials. :1078-1089
Biofilm implant-related infections cost the US healthcare system billions of dollars each year. For several decades, device coatings have been developed that actively release antimicrobial compounds in an attempt to prevent these infections from deve
Autor:
Roy D. Bloebaum, Kristofer D. Sinclair, L. A. Horne, Catherine Loc-Carrillo, Theresa X. Pham, S. H. Ingebretsen, Ryan W. Farnsworth, Dustin L. Williams
Publikováno v:
Journal of Biomedical Materials Research Part A. :2732-2738
More than 400,000 primary hip and knee replacement surgeries are performed each year in the United States. From these procedures, approximately 0.5–3% will become infected and when considering revision surgeries, this rate has been found to increas
Publikováno v:
The Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology. 294:831-838
The manner in which ligament connects to bone remains an area of interest for researchers, bioengineers, and clinicians. Stable fixation of an anterior cruciate ligament (ACL) graft has been shown to be paramount to preventing excess anterior tibial
Publikováno v:
Journal of Biomedical Materials Research Part A. :1194-1202
If tissue engineers are to successfully repair and regenerate native tendons and ligaments, it will be essential to implement contact guidance to induce cellular and type I collagen alignment to replicate the native structure. Capillary channel polym
Publikováno v:
Journal of biomedical materials research. Part B, Applied biomaterials. 104(8)
Periprosthetic joint infection (PJI) following total knee arthroplasty is a globally increasing procedural complication. These infections are difficult to treat and typically require revision surgery. Antibiotic-loaded bone cement is frequently utili