Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Kristof Theys"'
Autor:
Laise de Moraes, Moyra M. Portilho, Bram Vrancken, Frederik Van den Broeck, Luciane Amorim Santos, Marina Cucco, Laura B. Tauro, Mariana Kikuti, Monaise M. O. Silva, Gúbio S. Campos, Mitermayer G. Reis, Aldina Barral, Manoel Barral-Netto, Viviane Sampaio Boaventura, Anne-Mieke Vandamme, Kristof Theys, Philippe Lemey, Guilherme S. Ribeiro, Ricardo Khouri
Publikováno v:
Viruses, Vol 15, Iss 6, p 1236 (2023)
The Americas, particularly Brazil, were greatly impacted by the widespread Zika virus (ZIKV) outbreak in 2015 and 2016. Efforts were made to implement genomic surveillance of ZIKV as part of the public health responses. The accuracy of spatiotemporal
Externí odkaz:
https://doaj.org/article/abe6a6e6d445417dbd46758a79f7518d
Autor:
Andrea-Clemencia Pineda-Peña, Kristof Theys, Dora C. Stylianou, Ioannis Demetriades, SPREAD/ESAR Program, Ana B. Abecasis, Leondios G. Kostrikis
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract Since HIV-1 treatment is increasingly considered an effective preventionstrategy, it is important to study local HIV-1 epidemics to formulate tailored preventionpolicies. The prevalence of HIV-1 in Cyprus was historically low until 2005. To
Externí odkaz:
https://doaj.org/article/8e8bc87db2d7451982618405b7f165af
Publikováno v:
Frontiers in Public Health, Vol 7 (2019)
Genomic and epidemiological monitoring have become an integral part of our response to emerging and ongoing epidemics of viral infectious diseases. Advances in high-throughput sequencing, including portable genomic sequencing at reduced costs and tur
Externí odkaz:
https://doaj.org/article/458290e986be4a1a863f802c75527216
Autor:
Vagner Fonseca, Pieter J K Libin, Kristof Theys, Nuno R Faria, Marcio R T Nunes, Maria I Restovic, Murilo Freire, Marta Giovanetti, Lize Cuypers, Ann Nowé, Ana Abecasis, Koen Deforche, Gilberto A Santiago, Isadora C de Siqueira, Emmanuel J San, Kaliane C B Machado, Vasco Azevedo, Ana Maria Bispo-de Filippis, Rivaldo Venâncio da Cunha, Oliver G Pybus, Anne-Mieke Vandamme, Luiz C J Alcantara, Tulio de Oliveira
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 5, p e0007231 (2019)
In recent years, an increasing number of outbreaks of Dengue, Chikungunya and Zika viruses have been reported in Asia and the Americas. Monitoring virus genotype diversity is crucial to understand the emergence and spread of outbreaks, both aspects t
Externí odkaz:
https://doaj.org/article/4e43129addbc4996b003291af82e3d82
Autor:
Andrea-Clemencia Pineda-Peña, Marta Pingarilho, Guangdi Li, Bram Vrancken, Pieter Libin, Perpétua Gomes, Ricardo Jorge Camacho, Kristof Theys, Ana Barroso Abecasis, Portuguese HIV-1 Resistance Study Group
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0218226 (2019)
BACKGROUND:Portugal has one of the most severe HIV-1 epidemics in Western Europe. Two subtypes circulate in parallel since the beginning of the epidemic. Comparing their transmission patterns and its association with transmitted drug resistance (TDR)
Externí odkaz:
https://doaj.org/article/4fc9fc80ecf64a5d940d3ca8740d76c1
Publikováno v:
PLoS Genetics, Vol 14, Iss 12, p e1007855 (2018)
[This corrects the article DOI: 10.1371/journal.pgen.1007420.].
Externí odkaz:
https://doaj.org/article/d9aa9e751943493d90e76581fd9ef90d
Autor:
Marta Pingarilho, Victor Pimentel, Isabel Diogo, Sandra Fernandes, Mafalda Miranda, Andrea Pineda-Pena, Pieter Libin, Kristof Theys, M. Rosário O. Martins, Anne-Mieke Vandamme, Ricardo Camacho, Perpétua Gomes, Ana Abecasis, on behalf of the Portuguese HIV-1 Resistance Study Group
Publikováno v:
Viruses, Vol 12, Iss 11, p 1238 (2020)
Introduction: Treatment for All recommendations have allowed access to antiretroviral (ARV) treatment for an increasing number of patients. This minimizes the transmission of infection but can potentiate the risk of transmitted (TDR) and acquired dru
Externí odkaz:
https://doaj.org/article/eb61ec78b7774e02b5d00db38608bdd7
Publikováno v:
PLoS Genetics, Vol 14, Iss 6, p e1007420 (2018)
HIV has a high mutation rate, which contributes to its ability to evolve quickly. However, we know little about the fitness costs of individual HIV mutations in vivo, their distribution and the different factors shaping the viral fitness landscape. W
Externí odkaz:
https://doaj.org/article/7aff9f29ed0147fe985f882a1265aec8
Autor:
Ricardo Khouri, Gilvanéia Silva-Santos, Tim Dierckx, Soraya Maria Menezes, Daniele Decanine, Kristof Theys, Aline Clara Silva, Lourdes Farré, Achiléa Bittencourt, Massimo Mangino, Mario Roederer, Anne-Mieke Vandamme, Johan Van Weyenbergh
Publikováno v:
OncoImmunology, Vol 7, Iss 5 (2018)
Adult T-cell leukemia (ATL) is an aggressive, chemotherapy-resistant CD4+CD25+ leukemia caused by HTLV-1 infection, which usually develops in a minority of patients several decades after infection. IFN + AZT combination therapy has shown clinical ben
Externí odkaz:
https://doaj.org/article/a9fa303fef5449cfa137ed0f3e0fceea
Autor:
Lize Cuypers, Guangdi Li, Pieter Libin, Supinya Piampongsant, Anne-Mieke Vandamme, Kristof Theys
Publikováno v:
Viruses, Vol 7, Iss 9, Pp 5018-5039 (2015)
Treatment with pan-genotypic direct-acting antivirals, targeting different viral proteins, is the best option for clearing hepatitis C virus (HCV) infection in chronically infected patients. However, the diversity of the HCV genome is a major obstacl
Externí odkaz:
https://doaj.org/article/ade0d4f21e6040e6bef4de98aa7fe5e2