Viscoelastic Behavior of Supercooled and Glassy ASDs at Humid Conditions Can Be Predicted

Autor: Birte Grönniger, Andreas Danzer, Kristof Kimpe, Abhishek Singh, Gabriele Sadowski

Publikováno v: Molecular Pharmaceutics. 20:2568-2578

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::72cfda157169ca746771ceecae1cd799
https://doi.org/10.1021/acs.molpharmaceut.3c00008

Self-assembly of cyclodextrins and their complexes in aqueous solutions

Autor: Sabine Inghelbrecht, Govert W. Somsen, Albertina Arien, Phennapha Saokham, Alexey Ryzhakov, Kristof Kimpe, Thorsteinn Loftsson, Laura Bertoletti, Koen Schrijnemakers, Thao Do Thi, Sergey V. Kurkov, Jef Stappaerts, Patrick Augustijns, Guy Van den Mooter, M. Ilias Jimidar, André Rodrigues Sá Couto

Publikováno v: Journal of Pharmaceutical Sciences, 105(9), 2556-2569. John Wiley and Sons Inc.
Ryzhakov, A, DoThi, T, Stappaerts, J, Bertoletti, L, Kimpe, K, Rodrigues Sa Couto, A, Saokham, P, van den Mooter, G, Augustijns, P, Somsen, G W, Kurkov, S, Inghelbrecht 4, S, Arien, A, Jimidar, M I, Schrijnemakers, K & Loftsson, T 2016, ' Self-assembly of cyclodextrins and their complexes in aqueous solutions. ', Journal of Pharmaceutical Sciences, vol. 105, no. 9, pp. 2556-2569 . https://doi.org/10.1016/j.xphs.2016.01.019

Cyclodextrins (CDs) are enabling pharmaceutical excipients that can be found in numerous pharmaceutical products worldwide. Because of their favorable toxicologic profiles, CDs are often used in toxicologic and phase I assessments of new drug candida

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5d44a134e32be35670d7d87b458ef18
https://research.vu.nl/en/publications/708efab5-e270-4d31-82b4-cae30ba03a93

Abstract 5690: Discovery of JNJ-67856633: A novel, first-in-class MALT1 protease inhibitor for the treatment of B cell lymphomas

Autor: Ulrike Philippar, Tianbao Lu, Nele Vloemans, Mariette Bekkers, Luc Van Nuffel, Marcello Gaudiano, Katarzyna Wnuk-Lipinska, Bas-jan Van Der Leede, Katie Amssoms, Kristof Kimpe, Bart Medaer, Tony Greway, Yann Abraham, Max Cummings, Emanuele Trella, Greet Vanhoof, Weimei Sun, Jan Willem Thuring, Peter Connolly, Jan Linders, Haopeng Rui, Sriram Balasubramanian, Amy Johnson, John Gerecitano, Jenna Goldberg, James P. Edwards, Yusri Elsayed, Jennifer Smit, Jaqueline Bussolari, Ricardo Attar

Publikováno v: Cancer Research. 80:5690-5690

Introduction: Constitutive activation of the classical nuclear factor kappa-light-chain-enhancer of activated B-cells (NF-κB) pathway is a clear driver of B-cell lymphomas, especially the aggressive activated B-cell (ABC) subtype of diffuse large B-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::504dd7a5e5c4ecf52e6e466854e7daea
https://doi.org/10.1158/1538-7445.am2020-5690

A Self-Assembled Complex with a Titanium(IV) Catecholate Core as a Potential Bimodal Contrast Agent

Autor: Sophie Laurent, Kristof Kimpe, Geert Dehaen, Wim Dehaen, Robert N. Muller, Luce Vander Elst, Svetlana V. Eliseeva, Koen Binnemans, Tatjana N. Parac-Vogt

Publikováno v: Chemistry - A European Journal. 18:293-302

A ditopic chelating ligand (H(6)4) that bears catechol and diethylenetriamine-N,N,N',N'',N''-pentaacetate (DTPA) has been designed and shown to specifically bind lanthanide(III) ions at the DTPA core ([Ln(H(2)4)(H(2)O)](-)) and further self-assemble

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ddaaa39548161cce3c3e730a48a3734
https://doi.org/10.1002/chem.201101413

Paramagnetic liposomes containing amphiphilic bisamide derivatives of Gd-DTPA with aromatic side chain groups as possible contrast agents for magnetic resonance imaging

Autor: Corinne Piérart, Sophie Laurent, Koen Binnemans, Kristof Kimpe, Luce Vander Elst, Tatjana N. Parac-Vogt, Robert N. Muller

Publikováno v: European Biophysics Journal. 35:136-144

Three amphiphilic DTPA bisamide derivatives containing long-chain phenylalanine esters (with 14, 16 and 18 carbon atoms in the alkyl chain) were synthesized and their corresponding gadolinium(III) complexes were prepared. The attempts to form paramag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2de0c83327fd17874faf52e2ab4ed79
https://doi.org/10.1007/s00249-005-0024-8