Výsledky vyhledávání - "Kristine N Dye"

Akademický článek

Merkel cell polyomavirus Tumor antigens expressed in Merkel cell carcinoma function independently of the ubiquitin ligases Fbw7 and β-TrCP.

Autor: Kristine N Dye, Markus Welcker, Bruce E Clurman, Ann Roman, Denise A Galloway

Publikováno v: PLoS Pathogens, Vol 15, Iss 1, p e1007543 (2019)

Merkel cell polyomavirus (MCPyV) accounts for 80% of all Merkel cell carcinoma (MCC) cases through expression of two viral oncoproteins: the truncated large T antigen (LT-t) and small T antigen (ST). MCPyV ST is thought to be the main driver of cellu

Externí odkaz: https://doaj.org/article/4f1b05a618834a218d950755a744d4d6

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Akademický článek

The small tumor antigen of Merkel cell polyomavirus accomplishes cellular transformation by uniquely localizing to the nucleus despite the absence of a known nuclear localization signal

Autor: Kaira R. Thevenin, Isabella S. Tieche, Cody E. Di Benedetto, Matt Schrager, Kristine N. Dye

Publikováno v: Virology Journal, Vol 21, Iss 1, Pp 1-15 (2024)

Abstract Background Merkel Cell Carcinoma (MCC) is an aggressive skin cancer that is three times deadlier than melanoma. In 2008, it was found that 80% of MCC cases are caused by the genomic integration of a novel polyomavirus, Merkel Cell Polyomavir

Externí odkaz: https://doaj.org/article/7b5e497c798f4dd7919802c36850a8e4

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Akademický článek

Protocol to longitudinally quantify SARS-CoV-2 RNA in wastewater using RT-qPCR and pepper mild mottle virus normalization

Autor: Bryan Sanchez Jimenez, Trinity Sterling, Austin Brown, Brian Modica, Kaylee Gibson, Hannah Collins, Carolyn Koch, Tyler Schwarz, Kristine N. Dye

Publikováno v: STAR Protocols, Vol 5, Iss 2, Pp 103001- (2024)

Summary: Wastewater surveillance allows severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection levels to be tracked in a community. Here, we present a protocol to longitudinally quantify SARS-CoV-2 RNA in wastewater using quantitative

Externí odkaz: https://doaj.org/article/ba4bb64ef23042f398b43b85365032bb

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Merkel cell polyomavirus Tumor antigens expressed in Merkel cell carcinoma function independently of the ubiquitin ligases Fbw7 and β-TrCP

Autor: Kristine N. Dye, Bruce E. Clurman, Denise A. Galloway, Markus Welcker, Ann Roman

Publikováno v: PLoS Pathogens
PLoS Pathogens, Vol 15, Iss 1, p e1007543 (2019)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0c9c5258d920969e2e8ea61b40bcbd7
https://pubmed.ncbi.nlm.nih.gov/30689667

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Akademický článek

Wastewater surveillance in the COVID-19 post-emergency pandemic period: A promising approach to monitor and predict SARS-CoV-2 surges and evolution

Autor: Bryan Sanchez Jimenez, Trinity Sterling, Austin Brown, Brian Modica, Kaylee Gibson, Hannah Collins, Carolyn Koch, Tyler Schwarz, Kristine N. Dye

Publikováno v: Heliyon, Vol 9, Iss 11, Pp e22356- (2023)

On May 24, 2023, approximately 3.5 years into the pandemic, the World Health Organization (WHO) declared the end of the COVID-19 global health emergency. However, as there are still ∼3000 COVID-19 deaths per day in May 2023, robust surveillance sys

Externí odkaz: https://doaj.org/article/b1947c7e37c243fa9de59e9854affb3f

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