Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Kristine M. Wiren"'
Autor:
Deborah A. Finn, Joel G. Hashimoto, Debra K. Cozzoli, Melinda L. Helms, Michelle A. Nipper, Moriah N. Kaufman, Kristine M. Wiren, Marina Guizzetti
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
We previously determined that repeated binge ethanol drinking produced sex differences in the regulation of signaling downstream of Group 1 metabotropic glutamate receptors in the nucleus accumbens (NAc) of adult C57BL/6J mice. The purpose of the pre
Externí odkaz:
https://doaj.org/article/5d059925f3734e9a90a9cb3d464a9749
Publikováno v:
BioTechniques, Vol 36, Iss 1, Pp 54-60 (2004)
Externí odkaz:
https://doaj.org/article/e8ba317672e346c2b869947315e0211b
Autor:
Joel G. Hashimoto, Melissa Andrew, Kristine M. Wiren, Shelley H. Bloom, Melissa L. Roberts, Clare J. Wilhelm
Publikováno v:
Brain Pathology. 26:433-451
Chronic alcohol abuse is associated with brain damage in a sex-specific fashion, but the mechanisms involved are poorly described and remain controversial. Previous results have suggested that astrocyte gene expression is influenced by ethanol intoxi
Autor:
Rachel A Davey, Karey Cheong, Michele V Clarke, Jeffrey D Zajac, Howard A. Morris, Kristine M. Wiren, Patricia K Russell, Paul H. Anderson
Publikováno v:
Journal of Bone and Mineral Research. 30:809-823
Androgen action via the androgen receptor (AR) is essential for normal skeletal growth and bone maintenance post-puberty in males; however, the molecular and cellular mechanisms by which androgens exert their actions in osteoblasts remains relatively
Autor:
Shelley H. Bloom, Joel G. Hashimoto, Douglas K. Beard, Clare J. Wilhelm, Kristine M. Wiren, Melissa L. Roberts
Publikováno v:
Brain Research. 1601:102-116
Women are more sensitive to the harmful effects of alcohol (EtOH) abuse than men, yet the underlying mechanisms remain poorly understood. Previous gene expression analysis of the medial prefrontal cortex (mPFC) following a chronic intoxication paradi
Autor:
Kristine M. Wiren
Publikováno v:
Neuroscience Letters. 550:1-5
Publikováno v:
Neurotoxicology and teratology. 56
Alcohol abuse is associated with neurological dysfunction, brain morphological deficits and frank neurotoxicity. Although these disruptions may be a secondary effect due to hepatic encephalopathy, no clear evidence of causality is available. This stu
Publikováno v:
Bone. 49:662-672
Although androgen is considered an anabolic hormone, the consequences of androgen receptor (AR) overexpression in skeletally-targeted AR-transgenic lines highlight the detrimental effect of enhanced androgen sensitivity on cortical bone quality. A co
Publikováno v:
Journal of Cellular Biochemistry. 112:1773-1786
Androgens regulate body composition in youth and declining testosterone that occurs with aging is associated with muscle wasting, increased fat mass and osteopenia. Transgenic mice with targeted androgen receptor (AR) over-expression in mesenchymal s
Autor:
Melissa R. Forquer, Joel G. Hashimoto, Michelle A. Tanchuck, Deborah A. Finn, Kristine M. Wiren
Publikováno v:
Neuroscience. 173:57-75
Alcoholism is a relapsing disorder associated with excessive consumption after periods of abstinence. Neuroadaptations in brain structure, plasticity and gene expression occur with chronic intoxication but are poorly characterized. Here we report ide