Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kristine M. Cala"'
Publikováno v:
Molecular Endocrinology. 11:917-927
Female mice deficient in steroid 5alpha-reductase type 1 have a decreased litter size. The average litter in homozygous deficient females is 2.7 pups vs. 8.0 pups in wild type controls. Oogenesis, fertilization, implantation, and placental morphology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca5f358539c2adbfa2fdab52ccbb6f5a
https://doi.org/10.1210/mend.11.7.9933
https://doi.org/10.1210/mend.11.7.9933
Publikováno v:
Molecular Endocrinology. 10:380-392
Two steroid 5 alpha-reductase isozymes designated type 1 and 2 synthesize 5 alpha-reduced androgens and other 5 alpha-reduced steroid hormones. Naturally occurring mutations in the gene encoding 5 alpha-reductase type 2 cause male pseudohermaphroditi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fac1bdccc0518f109cf4214c9b62fdbb
https://doi.org/10.1210/mend.10.4.8721983
https://doi.org/10.1210/mend.10.4.8721983
Autor:
Kristine M. Cala, David W. Russell, Kyle Molberg, Joseph M. Guileyardo, John D. McConnell, Anice E. Thigpen
Publikováno v:
Journal of Urology. 155:975-981
Purpose: We isolated genes whose expression differs between normal and malignant prostate.Materials and Methods: Differential display polymerase chain reactions revealed a messenger ribonucleic acid (mRNA) with higher expression in prostatic adenocar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f54e5c47cea0b5db8f29033c7c10642
https://doi.org/10.1016/s0022-5347(01)66361-4
https://doi.org/10.1016/s0022-5347(01)66361-4
Publikováno v:
Journal of Biological Chemistry. 268:17404-17412
Membrane-bound isozymes of steroid 5 alpha-reductase, designated 1 and 2, synthesize the potent androgen, dihydrotestosterone. Isozyme 1 has an alkaline pH optimum (7.0-8.5), whereas isozyme 2 has an acidic pH optimum (5.0). To gain insight into this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cdb40d253e21ba79b40cb1ab1ec4f07c
https://doi.org/10.1016/s0021-9258(19)85349-8
https://doi.org/10.1016/s0021-9258(19)85349-8
Autor:
James S. Prihoda, David W. Russell, Daphne L. Davis, James T. Bryant, Richard I. Silver, Kristine M. Cala, David M. Berman, Anice E. Thigpen, W. Christian Wigley, Charles P. Landrum
Publisher Summary This chapter discusses the molecular genetics of steroid 5α-reductases. 5α-reductase plays a central role in androgen action by catalyzing the conversion of testosterone into the more potent hormone dihydrotestosterone. Like other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8ed0ba7b10003e23352ea8dba993c18
https://doi.org/10.1016/b978-0-12-571149-4.50018-0
https://doi.org/10.1016/b978-0-12-571149-4.50018-0
Autor:
C. Wayne Bardin, Eugene A. Berkowitz, David M. Berman, Susan Bonner-Weir, David L. Brautigan, Sondi Brown, Michael J. Brownstein, James T. Bryant, Dennis R. Burholt, E.R. Burns, Kristine M. Cala, Patrick J. Casey, William W. Chu, Donald S. Coffey, S.B. Conway, Daphne L. Davis, Jakob Dupont, Marilyn I. Evans, Stanley Friedman, Masato Fujisawa, Susan Gamble, Susan Garfinkel, D.W. Gietzen, Danling Gu, Joyce B. Higgins, Lyann R. Hodgskin, Beth J. Hoffman, W.G. Hope, Xiaoguo Hu, Anthony Jackson, Gary L. Johnson, L.-M. Kow, Narender Kumar, Charles P. Landrum, Carol A. Lange-Carter, A.H. Lauber, Xingquan Liu, P. Kay Lund, Thomas Maciag, Paul Mak, M.M. McCarthy, Arlene Mercado, John F. Moomaw, Patricia L. Morris, F. Murad, Maria I. New, Ishwar S. Parhar, Alan W. Partin, J.N. Pasley, Tony Pawson, D.W. Pfaff, Chris Pleiman, Sandra L. Polizotto, James S. Prihoda, Igor Prudovsky, P.L. Rayford, David W. Russell, Madhabananda Sar, Nora Sarvetnick, M. Schwanzel-Fukuda, William A. Segraves, Jianping Shi, Richard I. Silver, Phyllis W. Speiser, Elizabeth Stoner, Kalyan Sundaram, Francesca Tarantini, Anice E. Thigpen, Julia A. Thissen, M.A. Thompson-Reece, Donald J. Tindall, Fred W. Turek, Anthony N. Wakim, Jörg Wessendorf, Perrin C. White, W. Christian Wigley, Elizabeth M. Wilson, Choi-iok Wong, D.E. Woolley, Charles Y.-F. Young, Xi Zhan, Fang L. Zhang, Zhong-xun Zhou, Deguang Zhu, Ann Zimrin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abcc00d91f1705d83f31c98a5b0fb114
https://doi.org/10.1016/b978-0-12-571149-4.50003-9
https://doi.org/10.1016/b978-0-12-571149-4.50003-9