Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Kristine M, Wiren"'
Autor:
Deborah A. Finn, Joel G. Hashimoto, Debra K. Cozzoli, Melinda L. Helms, Michelle A. Nipper, Moriah N. Kaufman, Kristine M. Wiren, Marina Guizzetti
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
We previously determined that repeated binge ethanol drinking produced sex differences in the regulation of signaling downstream of Group 1 metabotropic glutamate receptors in the nucleus accumbens (NAc) of adult C57BL/6J mice. The purpose of the pre
Externí odkaz:
https://doaj.org/article/5d059925f3734e9a90a9cb3d464a9749
Publikováno v:
BioTechniques, Vol 36, Iss 1, Pp 54-60 (2004)
Externí odkaz:
https://doaj.org/article/e8ba317672e346c2b869947315e0211b
Publikováno v:
Alcohol. 60:83-94
Alcohol-use disorder (AUD) is a relapsing disorder associated with excessive ethanol consumption. Recent studies support the involvement of epigenetic mechanisms in the development of AUD. Studies carried out so far have focused on a few specific epi
Autor:
Joel G. Hashimoto, Melissa Andrew, Kristine M. Wiren, Shelley H. Bloom, Melissa L. Roberts, Clare J. Wilhelm
Publikováno v:
Brain Pathology. 26:433-451
Chronic alcohol abuse is associated with brain damage in a sex-specific fashion, but the mechanisms involved are poorly described and remain controversial. Previous results have suggested that astrocyte gene expression is influenced by ethanol intoxi
Autor:
Rachel A Davey, Karey Cheong, Michele V Clarke, Jeffrey D Zajac, Howard A. Morris, Kristine M. Wiren, Patricia K Russell, Paul H. Anderson
Publikováno v:
Journal of Bone and Mineral Research. 30:809-823
Androgen action via the androgen receptor (AR) is essential for normal skeletal growth and bone maintenance post-puberty in males; however, the molecular and cellular mechanisms by which androgens exert their actions in osteoblasts remains relatively
Autor:
Shelley H. Bloom, Joel G. Hashimoto, Douglas K. Beard, Clare J. Wilhelm, Kristine M. Wiren, Melissa L. Roberts
Publikováno v:
Brain Research. 1601:102-116
Women are more sensitive to the harmful effects of alcohol (EtOH) abuse than men, yet the underlying mechanisms remain poorly understood. Previous gene expression analysis of the medial prefrontal cortex (mPFC) following a chronic intoxication paradi
Autor:
Jeffrey D Zajac, Rachel A Davey, Evelyn S Marin, Michele V Clarke, Salvatore P. Mangiafico, Barbara C Fam, Sofianos Andrikopoulos, Kristine M. Wiren, Patricia K Russell
Publikováno v:
The Journal of endocrinology. 237(1)
It is well established that testosterone negatively regulates fat mass in humans and mice; however, the mechanism by which testosterone exerts these effects is poorly understood. We and others have shown that deletion of the androgen receptor (AR) in
Autor:
Michelle A. Tanchuck, Joel G. Hashimoto, Debra K. Cozzoli, Kristine M. Wiren, Deborah A. Finn, Moriah N. Strong-Kaufman
Publikováno v:
Alcoholism: Clinical and Experimental Research. 38:730-738
Background Binge ethanol (EtOH) intake during adolescence leads to an array of behavioral and cognitive consequences including elevated intake of EtOH during adulthood, with female mice showing greater susceptibility than males. Administration of the
Autor:
Kristine M. Wiren
Publikováno v:
Neuroscience Letters. 550:1-5
Publikováno v:
Neurotoxicology and teratology. 56
Alcohol abuse is associated with neurological dysfunction, brain morphological deficits and frank neurotoxicity. Although these disruptions may be a secondary effect due to hepatic encephalopathy, no clear evidence of causality is available. This stu