Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Kristine M, Swiderek"'
Autor:
Jennifer L. Gardell, Meghan E. Maurer, Monica M. Childs, Minh N. Pham, Brent Meengs, Susan H. Julien, Cong Tan, Daniel R. Boster, Phoenicia Quach, Jon H. Therriault, Gleda Hermansky, Daniel T. Patton, Justin Bowser, Alex Chen, Nadine N. Morgan, Emily A. Gilbertson, Lisa Bogatzki, Kaelen Encarnacion, Catherine J. McMahan, Courtney A. Crane, Kristine M. Swiderek
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionRegulatory CD8 T cells (CD8 Treg) are responsible for the selective killing of self-reactive and pathogenic CD4 T cells. In autoimmune disease, CD8 Treg may accumulate in the peripheral blood but fail to control the expansion of pathogeni
Externí odkaz:
https://doaj.org/article/1178caece79b4d0e9381fbb719b41a85
Autor:
Mark F. Maurer, Katherine E. Lewis, Joseph L. Kuijper, Dan Ardourel, Chelsea J. Gudgeon, Siddarth Chandrasekaran, Sherri L. Mudri, Kayla N. Kleist, Chris Navas, Martin F. Wolfson, Mark W. Rixon, Ryan Swanson, Stacey R. Dillon, Steven D. Levin, Yengo Raymond Kimbung, Masato Akutsu, Derek T. Logan, Björn Walse, Kristine M. Swiderek, Stanford L. Peng
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
CD28 costimulatory signalling can be suppressed by immune checkpoints, such as CTLA-4 and PD-1. Here the authors describe the design of the fusion therapeutic davoceticept (ALPN-202), based on a variant CD80 extracellular domain engineered to bind PD
Externí odkaz:
https://doaj.org/article/1c1e0e459c4147429eef80ef95841f04
Autor:
Stanford L. Peng, Martin F. Wolfson, Ryan Swanson, Steven D. Levin, LS Evans, Kristine M. Swiderek, E Rickel, Katherine E. Lewis, Stacey R. Dillon
Publikováno v:
Cancer Research. 79:P1-20
This abstract was withdrawn by the authors. Citation Format: Dillon SR, Evans LS, Rickel E, Lewis KE, Swanson R, Levin SD, Wolfson M, Peng SL, Swiderek KM. Withdrawn [abstract]. In: Proceedings of the 2018 San Antonio Breast Cancer Symposium; 2018 De
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff4a14b6df07797f3aa7616699327562
https://doi.org/10.1158/1538-7445.sabcs18-p1-20-03
https://doi.org/10.1158/1538-7445.sabcs18-p1-20-03
Autor:
Jennifer L Gardell, Courtney Crane, Justin Bowser, Rachael Fasnacht, Susan Julien, Meghan E Maurer, Megan Templeton, Jon Therriault, Su Jung Yang, Kristine M Swiderek
Publikováno v:
The Journal of Immunology. 208:174.16-174.16
INTRODUCTION Others have described a subset of CD8 T cells (CD8 Treg) with immunosuppressive characteristics in inflammatory disease settings. CD8 Treg activation through canonical T cell receptors results in their oligoclonal expansion and perforin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::921ba260a2271aec99abf8b402337c9e
https://doi.org/10.4049/jimmunol.208.supp.174.16
https://doi.org/10.4049/jimmunol.208.supp.174.16
Autor:
Courtney Crane, Justin Bowser, Rachael Fasnacht, Jennifer Gardell, Susan Julien, Meghan Maurer, Megan L. Templeton, Jon Therriault, Kristine M. Swiderek
Publikováno v:
Gastroenterology. 162:S-312
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12bbb8ec054b4f3498199292c92ef641
https://doi.org/10.1016/s0016-5085(22)60744-3
https://doi.org/10.1016/s0016-5085(22)60744-3
Autor:
Jing Yang, Steven D. Levin, Bruce R. Blazar, Kushi Kushekhar, Djamilatou Adom, Rebecca Wu, Katherine E. Lewis, Ryan Swanson, Hao Liu, Samantha Hund, Kristine M. Swiderek, Keli L. Hippen, Amanda Albright, Sophie Paczesny, Maykala Kirksey, Jinfeng Yang, Sherri Mudri, Stanford L. Peng, Erika Rickel, Katherine Henderson, Abdulraouf Ramadan, Lawrence Evans, Titilayo Adeniyan, Stacey R. Dillon, Michelle A. Seaberg, Martin F. Wolfson, Chelsea J. Gudgeon
Publikováno v:
Science Translational Medicine. 12
Acute graft-versus-host disease (aGVHD) remains a major complication of allogeneic hematopoietic cell transplantation (HCT). CD146 and CCR5 are proteins that mark activated T helper 17 (Th17) cells. The Th17 cell phenotype is promoted by the interact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a57e0ff14e221647243917f957d6962
https://doi.org/10.1126/scitranslmed.aay4799
https://doi.org/10.1126/scitranslmed.aay4799
Autor:
Djamilatou, Adom, Stacey R, Dillon, Jinfeng, Yang, Hao, Liu, Abdulraouf, Ramadan, Kushi, Kushekhar, Samantha, Hund, Amanda, Albright, Maykala, Kirksey, Titilayo, Adeniyan, Katherine E, Lewis, Lawrence, Evans, Rebecca, Wu, Steven D, Levin, Sherri, Mudri, Jing, Yang, Erika, Rickel, Michelle, Seaberg, Katherine, Henderson, Chelsea J, Gudgeon, Martin F, Wolfson, Ryan M, Swanson, Kristine M, Swiderek, Stanford L, Peng, Keli L, Hippen, Bruce R, Blazar, Sophie, Paczesny
Publikováno v:
Sci Transl Med
Acute graft-versus-host disease (aGVHD) remains a major complication of allogeneic hematopoietic cell transplantation (HCT). CD146 and CCR5 are proteins that mark activated T helper 17 (Th17) cells. The Th17 cell phenotype is promoted by the interact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::702e374a5e60a489b389152613e0b915
https://pubmed.ncbi.nlm.nih.gov/33028709
https://pubmed.ncbi.nlm.nih.gov/33028709
Autor:
Kristine M. Swiderek, Siddarth Chandrasekaran, Stanford L. Peng, Katherine E. Lewis, Steven D. Levin, Fariha Ahmed-Qadri, Sherri Mudri, Chelsea J. Gudgeon, Kayla N. Kleist, Stacey R. Dillon, Mark F. Maurer
Publikováno v:
Cancer Research. 80:LB-085
Background: Despite significant clinical benefit of checkpoint inhibitors (CPI) in some settings, unfortunately, the majority of patients still fail to respond and/or develop resistance. This is likely due to a complex set of factors including, but n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac9eadb257650bb7d4c069a5fd55fe08
https://doi.org/10.1158/1538-7445.am2020-lb-085
https://doi.org/10.1158/1538-7445.am2020-lb-085
Autor:
J. Bhandari, R. Wang, M. A. Seaberg, Katherine E. Lewis, D. Demonte, J. Yang, J. Kuijper, R. Sanderson, J. Hillson, M. F. Wolfson, S. L. Peng, L. S. Evans, S. Bort, F. Ahmed-Qadri, M. W. Rixon, Steven D. Levin, S. Mudri, Stacey R. Dillon, Kristine M. Swiderek, K. Kleist
Publikováno v:
Annals of the Rheumatic Diseases. 79:338.1-338
Background:BAFF and APRIL are TNF superfamily members that bind both TACI and BCMA on B cells; BAFF also binds BAFF-R. Together, BAFF and APRIL support B cell development, differentiation, and survival. Their co-neutralization dramatically reduces B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d983381ba4cf315ef442a96cb6e8e995
https://doi.org/10.1136/annrheumdis-2020-eular.1545
https://doi.org/10.1136/annrheumdis-2020-eular.1545
Autor:
Stacey R. Dillon, Lawrence S. Evans, Susan Bort, Sherri Mudri, Katherine Lewis, Mark Rixon, Janhavi Bhandari, Stanford Peng, Kristine M. Swiderek
Publikováno v:
Gastroenterology. 158:S-786
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::444132255847fdb68c092d95b94a2352
https://doi.org/10.1016/s0016-5085(20)32636-6
https://doi.org/10.1016/s0016-5085(20)32636-6