Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Kristine L Witt"'
Autor:
Aya Masaoka, Natalie R Gassman, Julie K Horton, Padmini S Kedar, Kristine L Witt, Cheryl A Hobbs, Grace E Kissling, Keizo Tano, Kenjiro Asagoshi, Samuel H Wilson
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66801 (2013)
The breast cancer 1 (BRCA1) protein is a tumor suppressor playing roles in DNA repair and cell cycle regulation. Studies of DNA repair functions of BRCA1 have focused on double-strand break (DSB) repair pathways and have recently included base excisi
Externí odkaz:
https://doaj.org/article/8c8ec1591f79421093a6465237cd408a
Autor:
Stephanie L. Smith‐Roe, Carol D. Swartz, Asma Rashid, Nicholas C. Christy, Jamie E. Sly, Xiaoqing Chang, Nisha S. Sipes, Keith R. Shockley, Shawn F. Harris, Sandra J. McBride, Gary J. Larson, Bradley J. Collins, Esra Mutlu, Kristine L. Witt
Publikováno v:
Environmental and Molecular Mutagenesis. 64:202-233
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd2947f3d2db52a359f6a1c16546e9bf
https://doi.org/10.1002/em.22534
https://doi.org/10.1002/em.22534
Autor:
Stephen D. Dertinger, Dingzhou Li, Carol Beevers, George R. Douglas, Robert H. Heflich, David P. Lovell, Daniel J. Roberts, Robert Smith, Yoshifumi Uno, Andrew Williams, Kristine L. Witt, Andreas Zeller, Changhui Zhou
Publikováno v:
Environmental and Molecular Mutagenesis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98ed77f417ad4664c6907cb385e09df2
https://doi.org/10.1002/em.22541
https://doi.org/10.1002/em.22541
Autor:
Stephanie L. Smith-Roe, Cheryl A. Hobbs, Victoria Hull, J. Todd Auman, Leslie Recio, Michael A. Streicker, Miriam V. Rivas, Gabriel A. Pratt, Fang Yin Lo, Jacob E. Higgins, Elizabeth K. Schmidt, Lindsey N. Williams, Daniela Nachmanson, Charles C. Valentine, Jesse J. Salk, Kristine L. Witt
Publikováno v:
bioRxiv
Duplex sequencing (DuplexSeq) is an error-corrected next-generation sequencing (ecNGS) method in which molecular barcodes informatically link PCR-copies back to their source DNA strands, enabling computational removal of errors by comparing grouped s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bc6e7afac422b90213086f574be3047
https://doi.org/10.1101/2023.05.08.539833
https://doi.org/10.1101/2023.05.08.539833
Autor:
Masato Ooka, Jinghua Zhao, Pranav Shah, Jameson Travers, Carleen Klumpp-Thomas, Xin Xu, Ruili Huang, Stephen Ferguson, Kristine L. Witt, Stephanie L. Smith-Roe, Anton Simeonov, Menghang Xia
Publikováno v:
Archives of Toxicology. 96:1975-1987
Currently, approximately 80,000 chemicals are used in commerce. Most have little-to-no toxicity information. The U.S. Toxicology in the 21st Century (Tox21) program has conducted a battery of in vitro assays using a quantitative high-throughput scree
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::431c2157e9565782aadd368c1e0ccdc4
https://doi.org/10.1007/s00204-022-03291-5
https://doi.org/10.1007/s00204-022-03291-5
Autor:
Eunnara Cho, Carol D. Swartz, Andrew Williams, Miriam Rivas, Leslie Recio, Kristine L. Witt, Elizabeth K. Schmidt, Jeffry Yaplee, Thomas H. Smith, Phu Van, Fang Yin Lo, Charles C. Valentine, Jesse J. Salk, Francesco Marchetti, Stephanie L. Smith-Roe, Carole L. Yauk
Error-corrected Duplex Sequencing (DuplexSeq) enables direct quantification of low-frequency mutations and offers tremendous potential for chemical mutagenicity assessment. We investigated the utility of DuplexSeq to quantify induced mutation frequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0297e7108e98c4ad7df2f12bf5adc5ad
https://doi.org/10.1101/2023.02.22.529418
https://doi.org/10.1101/2023.02.22.529418
Autor:
Stephanie L. Smith‐Roe, Stavros Garantziotis, Rebecca L. Church, Jeffrey C. Bemis, Dorothea K. Torous, Kim G. Shepard, Cheryl A. Hobbs, Suramya Waidyanatha, Esra Mutlu, Keith R. Shockley, Grace E. Kissling, Sandra J. McBride, Guanhua Xie, Tim Cristy, Jessica Pierfelice, Kristine L. Witt
Publikováno v:
Environ Mol Mutagen
Black cohosh (BC; Actaea racemosa L.), a top-selling botanical dietary supplement, is marketed to women primarily to ameliorate a variety of gynecological symptoms. Due to widespread usage, limited safety information, and sporadic reports of hepatoto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da8568690d0ac87ececd0accb59d33cb
https://europepmc.org/articles/PMC10018809/
https://europepmc.org/articles/PMC10018809/
Autor:
Francesco Marchetti, Renato Cardoso, Connie L. Chen, George R. Douglas, Joanne Elloway, Patricia A. Escobar, Tod Harper Jr, Robert H. Heflich, Darren Kidd, Anthony M. Lynch, Meagan B. Myers, Barbara L. Parsons, Jesse J. Salk, Raja S. Settivari, Stephanie L. Smith-Roe, Kristine L. Witt, Carole Yauk, Robert R. Young, Shaofei Zhang, Sheroy Minocherhomji
Publikováno v:
Nature Reviews Drug Discovery. 22:165-166
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0999889d4ce03b2372e3772a32b4bdb2
https://doi.org/10.1038/d41573-023-00014-y
https://doi.org/10.1038/d41573-023-00014-y
Publikováno v:
Toxicol Lett
Luteolin (5,7,3′,4′-tetrahydroxyflavone) belongs to the flavone subclass of flavonoids. Luteolin and its glycosides are present in many botanical families, including edible plants, fruits, and vegetables. While the beneficial properties of luteol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5b8bebe95a33df808f542bd82deed1d
https://doi.org/10.1016/j.toxlet.2021.03.006
https://doi.org/10.1016/j.toxlet.2021.03.006
Autor:
Sharon D. Shelton, Ying Chen, Ji-Eun Seo, Dayton M. Petibone, Nan Mei, Mugimane G. Manjanatha, Xiaoqing Guo, Xilin Li, Stephanie L. Smith-Roe, Volodymyr Tryndyak, Kristine L. Witt
Publikováno v:
Toxicol Sci
Black cohosh extract (BCE) is marketed to women as an alternative to hormone replacement therapy for alleviating menopausal symptoms. Previous studies by the National Toxicology Program revealed that BCE induced micronuclei (MN) and a nonregenerative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74da9d17631bb1cc3a8e0c42999ffa1f
https://doi.org/10.1093/toxsci/kfab044
https://doi.org/10.1093/toxsci/kfab044