Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Kristine Kikly"'
Autor:
Jeffrey S. Boyles, Catherine B. Beidler, Beth A. Strifler, Daniel S. Girard, Zhanna Druzina, Jim D. Durbin, Michelle L. Swearingen, Linda N. Lee, Kristine Kikly, Sudhakar Chintharlapalli, Derrick R. Witcher
Publikováno v:
mAbs, Vol 12, Iss 1 (2020)
CXCR1 and CXCR2 signaling play a critical role in neutrophil migration, angiogenesis, and tumorigenesis and are therefore an attractive signaling axis to target in a variety of indications. In human, a total of seven chemokines signal through these r
Externí odkaz:
https://doaj.org/article/c12f43a910904fb9bb6a520c72c2939d
Autor:
William A. Rose, Angela J. Okragly, Ningjie N. Hu, Montanea R. Daniels, Andrea P. Martin, Yi Ting Koh, Kristine Kikly, Robert J. Benschop
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Breaking tolerance is a key event leading to autoimmunity, but the exact mechanisms responsible for this remain uncertain. Here we show that the alarmin IL-33 is able to drive the generation of autoantibodies through induction of the B cell survival
Externí odkaz:
https://doaj.org/article/d1228f9ab1f94cada93acf6e5a47d8bd
Autor:
Ferry Cornelissen, Patrick S Asmawidjaja, Adriana M C Mus, Odilia Corneth, Kristine Kikly, Erik Lubberts
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57553 (2013)
IL-23p19 deficient mice have revealed a critical role of IL-23 in the development of experimental autoimmune diseases, such as collagen-induced arthritis (CIA). Neutralizing IL-23 after onset of CIA in rats has been shown to reduce paw volume, but th
Externí odkaz:
https://doaj.org/article/2ec8a3408ecb4e97b30e3e3e613925ab
Autor:
Michael W. Lark, Christine Debouck, Kalindi Vaidya, Mark E. Nuttall, Kyung O. Johanson, James D. Winkler, Alison M. Badger, Martha S. Head, Paul M. Keller, Mark Alan Levy, R. Curtis Haltiwanger, Larry J. Suva, Cheryl A. Janson, Sherin S. Abdel-Meguid, Po-Huang Liang, Patrick McDevitt, George K. Chan, Nestor O. Concha, Daniel P. Nadeau, Kristine Kikly, Dennis Lee, Scott A. Long, Winnie Chan, Walter E. DeWolf, Ryan M Dominic, Susan B. Richardson, Maxine Gowen, Thaddeus A. Tomaszek, Terry A. Francis, Chiu-Mei Sung, Jerry L. Adams
Publikováno v:
Journal of Biological Chemistry. 275:16007-16014
Caspases have been strongly implicated to play an essential role in apoptosis. A critical question regarding the role(s) of these proteases is whether selective inhibition of an effector caspase(s) will prevent cell death. We have identified potent a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68ab9cad81cf835eb754a9108b2beebb
https://doi.org/10.1074/jbc.275.21.16007
https://doi.org/10.1074/jbc.275.21.16007
Autor:
Paul M. Keller, David P. Brooks, Dennis Lee, Walter E. DeWolf, Kristine Kikly, Victoria Y. Wong, Todd A. Fredrickson, Shujath M. Ali
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 278:R763-R769
Polycystic kidney disease (PKD) is characterized by the development of large renal cysts and progressive loss of renal function. Although the cause of the development of renal cysts is unknown, recent evidence suggests that excessive apoptosis occurs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12e4e5e45053bfee170fb11007044e54
https://doi.org/10.1152/ajpregu.2000.278.3.r763
https://doi.org/10.1152/ajpregu.2000.278.3.r763
Autor:
Helen, Benham, Linda M, Rehaume, Sumaira Z, Hasnain, Jared, Velasco, Athan C, Baillet, Merja, Ruutu, Kristine, Kikly, Ran, Wang, Hsu-Wen, Tseng, Gethin P, Thomas, Matthew A, Brown, Geoffrey, Strutton, Michael A, McGuckin, Ranjeny, Thomas
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.). 66(7)
Spondyloarthritides (SpA) occur in 1% of the population and include ankylosing spondylitis (AS) and arthropathy of inflammatory bowel disease (IBD), with characteristic spondylitis, arthritis, enthesitis, and IBD. Genetic studies implicate interleuki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3c9ab28d2f200f38753c267444ee42d0
https://pubmed.ncbi.nlm.nih.gov/24664521
https://pubmed.ncbi.nlm.nih.gov/24664521
Autor:
Eugene T. Grygielko, Kristine Kikly, Victoria Y. Wong, Paul M. Keller, Mark E. Nuttall, David P. Brooks, Daniel P. Nadeau, Walter E. DeWolf, Dennis Lee, Shujath M. Ali, Nicholas J. Laping
Publikováno v:
European journal of pharmacology. 433(2-3)
In the present study, we have used an in vitro model of apoptosis using primary human renal proximal tubular epithelial (RPTE) cells to investigate the mechanisms involved in renal cell apoptosis. Treatment of RPTE cells with okadaic acid for 24-48 h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faad2aab0f3cad25cf46c1937ae87a36
https://pubmed.ncbi.nlm.nih.gov/11755144
https://pubmed.ncbi.nlm.nih.gov/11755144
Autor:
Mark A. Levy, James D. Winkler, Jerry L. Adams, Sung Cm, Dennis Lee, Long Sa, Kristine Kikly, Daniel P. Nadeau, Paul M. Keller, Walter E. DeWolf, Ryan, Mark E. Nuttall, Murray Jh
Publikováno v:
Journal of medicinal chemistry. 44(12)
5-Dialkylaminosulfonylisatins have been identified as potent, nonpeptide inhibitors of caspases 3 and 7. The most active compound within this series (34) inhibited caspases 3 and 7 in the 2-6 nM range and exhibited approximately 1000-fold selectivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d73ae14be10f985ed1d195c0492d56f
https://pubmed.ncbi.nlm.nih.gov/11384246
https://pubmed.ncbi.nlm.nih.gov/11384246
Autor:
Luciano Adorini, Matthew L. Albert, Paola Allavena, Francesca Aloisi, Sebastian Amigorena, Fabrice André, Jonathan M. Austyn, Jacques Banchereau, Penelope A. Bedford, Donna Beer Stolz, Nina Bhardwaj, C. Allen Black, Yuri V. Bobryshev, Francine Brière, Jozef Borvak, Christophe Caux, Jonathan Cebon, Vito R. Cicinnati, S. Citterio, Georgina J. Clark, L. Cochand, Sandra Columba Cabezas, Tyler J. Curiel, Ian Davis, Anthony J. Demetris, Xin Dong, Bertrand Dubois, Louis D. Falo, Lian Fan, Jerome Fayette, Nadine C. Fernandez, I. Frank, S. Schlesinger Frankel, Lawrence Fong, Jean-François Fonteneau, John V. Forrester, John J. Fung, Thomas F. Gajewski, Anne Galy, Andrea Gambotto, Wendy S. Garrett, Angela Granelli-Piperno, F. Granucci, A.M. Gudin, Derek N.J. Hart, S.T. Holgate, J.A. Holloway, Fang-Ping Huang, R. Ignatius, Tatyana Isaeva, Ronald Jaffe, Nori Kadowaki, Pawel Kalinski, Martien L. Kapsenberg, Kristine Kikly, Stella C. Knight, Marie H. Kosco-Vilbois, Adriana T. Larregina, Marie Larsson, Andrew Lee, Li Ming Liu, Yong-Jun Liu, David Lo, Michael T. Lotze, Lina Lu, Thomas Luft, Kelli MacDonald, G. Gordon MacPherson, Thomas C. Manning, Alberto Mantovani, Eugene Maraskovsky, Florentina Marches, Carole Masurier, Hiroyuki Matsue, Dieter Maurer, Paul G. McMenamin, Ira Mellman, D. Messmer, Michael Murphey-Corb, Noriko Murase, Laurent P. Nicod, Karen A. Norris, Peta J. O'Connell, Glenn D. Papworth, Karolina Palucka, Melissa Pope, Bali Pulendran, Paul Racz, Gwendalyn J. Randolph, Graça Raposo, Will Redmond, Armelle Regnault, Christina R. Reilly, M. Rescigno, Paola Ricciardi Castagnoli, M. Rittig, Paul D. Robbins, Russell D. Salter, Amanda E. Semper, Barbara Serafini, Vassili Soumelis, Silvano Sozzani, Hergen Spits, C. Stahl-Hennig, Ralph M. Steinman, Raymond J. Steptoe, Georg Stingl, Akira Takashima, K. Tenner-Racz, Magali Terme, Clotilde Théry, Ranjeny Thomas, Angus W. Thomson, M. Urbano, B. Valzasina, Stephane Vandenabeele, Slavica Vuckovic, Simon C. Watkins, Shuang Wei, Jeffrey Weber, Cara C. Wilson, Joseph Wolfers, Li Wu, L. Zhong, Laurence Zitvogel, Weiping Zou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5187118b83e6497cf57d66d05929d4ee
https://doi.org/10.1016/b978-012455851-9/50036-5
https://doi.org/10.1016/b978-012455851-9/50036-5
Autor:
Kristine Kikly, Michael T. Lotze
Publikováno v:
Dendritic Cells (Second Edition)
Abnormal or prolonged wound healing can occur due to underlying disease pathogenesis, such as diabetes or chronic venous insufficiency, or as a result of wound size or depth. Infection can also contribute to prolongation or deviation from the normal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56f9308ad9c57bacdbf2838a9f28e46a
https://doi.org/10.1016/b978-012455851-9/50077-8
https://doi.org/10.1016/b978-012455851-9/50077-8