Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kristine K. Deibler"'
Autor:
Dalton R. Kim, Meghan J. Orr, Ada J. Kwong, Kristine K. Deibler, Hasan H. Munshi, Cory Seth Bridges, Taylor Jie Chen, Xiaoyu Zhang, H. Daniel Lacorazza, Karl A. Scheidt
Publikováno v:
ACS Medicinal Chemistry Letters. 14:606-613
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0903b6a3fed7dbb1c35e9c053f680bf
https://doi.org/10.1021/acsmedchemlett.3c00029
https://doi.org/10.1021/acsmedchemlett.3c00029
Autor:
Kristine K. Deibler, Gary E. Schiltz, Matthew R. Clutter, Raymond C. Bergan, Purav P. Vagadia, Karl A. Scheidt, Matthew S. O'Connor, Rama K. Mishra
Publikováno v:
J Chem Inf Model
MEK4, mitogen-activated protein kinase kinase 4, is overexpressed and induces metastasis in advanced prostate cancer lesions. However, the value of MEK4 as an oncology target has not been pharmacologically validated because selective chemical probes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71d1106f7a947bd5d06500a1ab395547
https://doi.org/10.1021/acs.jcim.9b00490
https://doi.org/10.1021/acs.jcim.9b00490
Publikováno v:
Advanced Synthesis & Catalysis. 360:1719-1725
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d72c4d7dc26dde19f1106b8673ac3a3
https://doi.org/10.1002/adsc.201800160
https://doi.org/10.1002/adsc.201800160
Autor:
Raymond C. Bergan, Mariam Donny George, Karl A. Scheidt, Purav P. Vagadia, Gary E. Schiltz, Matthew R. Clutter, Ryan R. Gordon, Graham Fowler, Kristine K. Deibler, Rama K. Mishra, Matthew S. O'Connor
Publikováno v:
ChemMedChem. 14(6)
Herein we report the discovery of a novel series of highly potent and selective mitogen-activated protein kinase kinase 4 (MEK4) inhibitors. MEK4 is an upstream kinase in MAPK signalling pathways that phosphorylates p38 MAPK and JNK in response to mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6d6ae682df47fd43d107185ddb71f3c
https://pubmed.ncbi.nlm.nih.gov/30707493
https://pubmed.ncbi.nlm.nih.gov/30707493
Autor:
Uno, Brice E.1 (AUTHOR), Deibler, Kristine K.1 (AUTHOR), Villa, Carlos2 (AUTHOR), Raghuraman, Arjun2 (AUTHOR), Scheidt, Karl A.1 (AUTHOR) scheidt@northwestern.edu
Publikováno v:
Advanced Synthesis & Catalysis. 4/17/2018, Vol. 360 Issue 8, p1719-1725. 7p. 1 Color Photograph, 1 Diagram, 4 Charts, 2 Graphs.
Autor:
Deibler, Kristine K., Schiltz, Gary E., Clutter, Matthew R., Mishra, Rama K., Vagadia, Purav P., O'Connor, Matthew, George, Mariam Donny, Gordon, Ryan, Fowler, Graham, Bergan, Raymond, Scheidt, Karl A.
Publikováno v:
ChemMedChem; 3/22/2019, Vol. 14 Issue 6, p615-620, 6p
Publikováno v:
Pediatrics Week; 6/2/2023, p278-278, 1p