Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kristine Hahn"'
Autor:
Ashley L. Buchanan, Jill M. Kolesar, Rita Axelrod, Athanassios Argiris, Musie Ghebremichael, Kristine Hahn, Michael R. Pins, Arlene A. Forastiere, Bruce Brockstein
Publikováno v:
Cancer. 115:4504-4513
Docetaxel and irinotecan have single-agent antitumor activity in squamous cell carcinoma of the head and neck (SCCHN). The authors sought to evaluate their combination in the treatment of patients with recurrent or metastatic SCCHN.Eligibility criter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69092f2db2b2057c76e7649281e71757
https://doi.org/10.1002/cncr.24528
https://doi.org/10.1002/cncr.24528
Publikováno v:
Journal of Oncology Pharmacy Practice. 10:169-175
Objective. Provide a review and update of gefitinib (Iressa®), including recent data on mutations in the epidermal growth factor receptor (EGFR) and possible implications in non-small cell lung cancer patients. Data sources. Primary literature and r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0ac0f8b85032b90f7bc3edf2a4563a6
https://doi.org/10.1191/1078155204jp130oa
https://doi.org/10.1191/1078155204jp130oa
Publikováno v:
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners. 16(1)
Background. P-glycoprotein (Pgp) is a drug efflux pump that transports natural products, including taxanes and other chemotherapeutic agents, from cells. Several frequent polymorphisms in ATP binding cassette gene B1 (ABCB1) may influence Pgp levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f84befbaeb537132fd9bdfd53f51167
https://pubmed.ncbi.nlm.nih.gov/19401306
https://pubmed.ncbi.nlm.nih.gov/19401306
Autor:
Kyle D. Holen, Dona Alberti, Jens C. Eickhoff, Percy Ivy, Steven Attia, Anne M. Traynor, William R. Schelman, Wei Huang, Jill M. Kolesar, Kristine Hahn, George Wilding
The purpose of this study was to evaluate baseline RRM2 protein and gene expression in tumors of patients receiving 3-AP.Tumor blocks from patients enrolled in phase I and II clinical studies using 3-AP, were evaluated for RRM2 gene and protein expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9a9b8b51be1485e34a4dab54e9facc9
https://europepmc.org/articles/PMC3043989/
https://europepmc.org/articles/PMC3043989/
Publikováno v:
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists. 63(22)
Purpose. Irinotecan metabolism, irinotecan pharmacogenetic research, and the role of genetic testing before administration of the drug are reviewed. Summary. Irinotecan is approved worldwide for the treatment of metastatic colorectal cancer but cause
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38e8399d7ec45585241107253f242523
https://pubmed.ncbi.nlm.nih.gov/17090748
https://pubmed.ncbi.nlm.nih.gov/17090748
Publikováno v:
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists. 62(15)
Purpose. The pharmacology, pharmacokinetics, clinical efficacy, dosage and administration, and safety of azacitidine are reviewed. Summary. Azacitidine is the first drug in a new class of compounds, known as DNA hypomethylating agents, to receive FDA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a44cf8f500b03f68f5ad40c4f0f8a43
https://pubmed.ncbi.nlm.nih.gov/16030365
https://pubmed.ncbi.nlm.nih.gov/16030365