Data from Chronic Recreational Physical Inactivity and Epithelial Ovarian Cancer Risk: Evidence from the Ovarian Cancer Association Consortium

Autor: Kirsten B. Moysich, Linda E. Kelemen, Kathryn L. Terry, Joellen M. Schildkraut, Francesmary Modugno, Anna H. Wu, Stacey J. Winham, Kristine G. Wicklund, Nicolas Wentzensen, Penelope M. Webb, Robert A. Vierkant, Chiu-Chen Tseng, Pamela J. Thompson, Elizabeth A. Szamreta, Mary Anne Rossing, Malcolm C. Pike, Celeste Leigh Pearce, Sara H. Olson, Catherine M. Olsen, Roberta B. Ness, Keitaro Matsuo, Susanne K. Kjaer, Susan Jordan, Allan Jensen, Satoyo Hosono, Estrid Hogdall, Marc T. Goodman, Ellen L. Goode, Brooke L. Fridley, Robert P. Edwards, Jennifer A. Doherty, Daniel Cramer, Andrew Berchuck, Elisa V. Bandera, Gary R. Zirpoli, Albina N. Minlikeeva, Emily Gower, Ruediger Klapdor, Barbara Schmalfeldt, Jenny Chang-Claude, J. Brian Szender, Kevin H. Eng, Lara E. Sucheston-Campbell, Chi-Chen Hong, Harvey A. Risch, Michael J. LaMonte, Rikki Cannioto

Background: Despite a large body of literature evaluating the association between recreational physical activity and epithelial ovarian cancer (EOC) risk, the extant evidence is inconclusive, and little is known about the independent association betw

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a7787a6aa4b78c12197d5dfcc7973a8
https://doi.org/10.1158/1055-9965.c.6515380

Supplementary Tables S1-6, Figures S1-2 from Network-Based Integration of GWAS and Gene Expression Identifies a HOX-Centric Network Associated with Serous Ovarian Cancer Risk

Autor: Paul D.P. Pharoah, Simon A. Gayther, Matthew L. Freedman, Alvaro N.A. Monteiro, Thomas A. Sellers, Argyrios Ziogas, Wei Zheng, Hannah Yang, Anna Wu, Xifeng Wu, Yin-Ling Woo, Lynne R. Wilkens, Kristine G. Wicklund, Alice S. Whittemore, Nicolas Wentzensen, Christine Walsh, Shan Wang-Gohrke, Robert A. Vierkant, Ignace Vergote, Els Van Nieuwenhuysen, Anne M. van Altena, Shelley S. Tworoger, Ya-Yu Tsai, Agnieszka Timorek, Pamela J. Thompson, Kathryn L. Terry, Soo-Hwang Teo, Ingvild L. Tangen, Lara E. Sucheston-Campbell, Melissa C. Southey, Honglin Song, Weiva Sieh, Nadeem Siddiqui, Yurii B. Shvetsov, Xiao-Ou Shu, Ira Schwaab, Joellen M. Schildkraut, Helga B. Salvesen, Iwona K. Rzepecka, Ingo B. Runnebaum, Anja Rudolph, Joseph H. Rothstein, Mary Anne Rossing, Barry Rosen, Harvey A. Risch, Susan J. Ramus, Elizabeth M. Poole, Malcolm C. Pike, Catherine M. Phelan, Jennifer Permuth-Wey, Liisa M. Pelttari, Tanja Pejovic, Celeste Leigh Pearce, Rachel Palmieri Weber, Sandra Orsulic, Irene Orlow, Sara H. Olson, Kunle Odunsi, Heli Nevanlinna, Roberta B. Ness, Lotte Nedergaard, Steven A. Narod, Kirsten B. Moysich, Francesmary Modugno, Usha Menon, Iain A. McNeish, John R. McLaughlin, Valerie McGuire, Keitaro Matsuo, Leon Massuger, Lene Lundvall, Jan Lubinski, Karen Lu, Jolanta Lissowska, Dong Liang, Douglas A. Levine, Jenny Lester, Arto Leminen, Shashi Lele, Alice W. Lee, Nhu D. Le, Sandrina Lambrechts, Diether Lambrechts, Jolanta Kupryjanczyk, Camilla Krakstad, Lambertus A. Kiemeney, Joseph Kelley, Melissa Kellar, Linda E. Kelemen, Susanne K. Kjaer, Beth Y. Karlan, Bu-Tian Ji, Allan Jensen, James Paul, Anna Jakubowska, Edwin S. Iversen, Satoyo Hosono, Claus K. Hogdall, Estrid Hogdall, Peter Hillemanns, Michelle A.T. Hildebrandt, Florian Heitz, Alexander Hein, Philipp Harter, Patricia Harrington, Jacek Grownwald, Marc T. Goodman, Ellen L. Goode, Rosalind Glasspool, Graham G. Giles, Aleksandra Gentry-Maharaj, Yu-Tang Gao, Brooke L. Fridley, Peter A. Fasching, Arif B. Ekici, Robert P. Edwards, Douglas F. Easton, Diana Eccles, Matthias Dürst, Andreas du Bois, Thilo Dörk, Jennifer A. Doherty, Ed Dicks, Joe Dennis, Agnieszka Dansonka-Mieszkowska, Cezary Cybulski, Julie M. Cunningham, Daniel Cramer, Linda S. Cook, Zhihua Chen, Yian Ann Chen, Jenny Chang-Claude, Karen Carty, Ian Campbell, Ralf Butzow, Angela Brooks-Wilson, Louise Brinton, Natalia Bogdanova, Line Bjørge, Maria Bisogna, Andrew Berchuck, Matthias W. Beckmann, Yukie T. Bean, Elisa V. Bandera, Helen Baker, Georgia Chenevix-Trench, Natalia Antonenkova, Hoda Anton-Culver, Katja K.H. Aben, Kate Lawrenson, Qiyuan Li, Jonathan P. Tyrer, Siddhartha P. Kar

Supplementary Tables S1-6, Figures S1-2. Supplementary Table S1: Summary of serous EOC GWAS data sets; Supplementary Table S2: Genes in the six significant co-expression networks; Supplementary Table S3: GSEA results after LD-based clumping of SNPs;

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71665f5b81b92c933e3446242aa17c39
https://doi.org/10.1158/1055-9965.22437577.v1

Common Genetic Variation In Cellular Transport Genes and Epithelial Ovarian Cancer (EOC) Risk.

Autor: Ganna Chornokur, Hui-Yi Lin, Jonathan P Tyrer, Kate Lawrenson, Joe Dennis, Ernest K Amankwah, Xiaotao Qu, Ya-Yu Tsai, Heather S L Jim, Zhihua Chen, Ann Y Chen, Jennifer Permuth-Wey, Katja K H Aben, Hoda Anton-Culver, Natalia Antonenkova, Fiona Bruinsma, Elisa V Bandera, Yukie T Bean, Matthias W Beckmann, Maria Bisogna, Line Bjorge, Natalia Bogdanova, Louise A Brinton, Angela Brooks-Wilson, Clareann H Bunker, Ralf Butzow, Ian G Campbell, Karen Carty, Jenny Chang-Claude, Linda S Cook, Daniel W Cramer, Julie M Cunningham, Cezary Cybulski, Agnieszka Dansonka-Mieszkowska, Andreas du Bois, Evelyn Despierre, Ed Dicks, Jennifer A Doherty, Thilo Dörk, Matthias Dürst, Douglas F Easton, Diana M Eccles, Robert P Edwards, Arif B Ekici, Peter A Fasching, Brooke L Fridley, Yu-Tang Gao, Aleksandra Gentry-Maharaj, Graham G Giles, Rosalind Glasspool, Marc T Goodman, Jacek Gronwald, Patricia Harrington, Philipp Harter, Alexander Hein, Florian Heitz, Michelle A T Hildebrandt, Peter Hillemanns, Claus K Hogdall, Estrid Hogdall, Satoyo Hosono, Anna Jakubowska, Allan Jensen, Bu-Tian Ji, Beth Y Karlan, Linda E Kelemen, Mellissa Kellar, Lambertus A Kiemeney, Camilla Krakstad, Susanne K Kjaer, Jolanta Kupryjanczyk, Diether Lambrechts, Sandrina Lambrechts, Nhu D Le, Alice W Lee, Shashi Lele, Arto Leminen, Jenny Lester, Douglas A Levine, Dong Liang, Boon Kiong Lim, Jolanta Lissowska, Karen Lu, Jan Lubinski, Lene Lundvall, Leon F A G Massuger, Keitaro Matsuo, Valerie McGuire, John R McLaughlin, Iain McNeish, Usha Menon, Roger L Milne, Francesmary Modugno, Kirsten B Moysich, Roberta B Ness, Heli Nevanlinna, Ursula Eilber, Kunle Odunsi, Sara H Olson, Irene Orlow, Sandra Orsulic, Rachel Palmieri Weber, James Paul, Celeste L Pearce, Tanja Pejovic, Liisa M Pelttari, Malcolm C Pike, Elizabeth M Poole, Harvey A Risch, Barry Rosen, Mary Anne Rossing, Joseph H Rothstein, Anja Rudolph, Ingo B Runnebaum, Iwona K Rzepecka, Helga B Salvesen, Eva Schernhammer, Ira Schwaab, Xiao-Ou Shu, Yurii B Shvetsov, Nadeem Siddiqui, Weiva Sieh, Honglin Song, Melissa C Southey, Beata Spiewankiewicz, Lara Sucheston, Soo-Hwang Teo, Kathryn L Terry, Pamela J Thompson, Lotte Thomsen, Ingvild L Tangen, Shelley S Tworoger, Anne M van Altena, Robert A Vierkant, Ignace Vergote, Christine S Walsh, Shan Wang-Gohrke, Nicolas Wentzensen, Alice S Whittemore, Kristine G Wicklund, Lynne R Wilkens, Anna H Wu, Xifeng Wu, Yin-Ling Woo, Hannah Yang, Wei Zheng, Argyrios Ziogas, Hanis N Hasmad, Andrew Berchuck, Georgia Chenevix-Trench, AOCS management group, Edwin S Iversen, Joellen M Schildkraut, Susan J Ramus, Ellen L Goode, Alvaro N A Monteiro, Simon A Gayther, Steven A Narod, Paul D P Pharoah, Thomas A Sellers, Catherine M Phelan

Publikováno v: PLoS ONE, Vol 10, Iss 6, p e0128106 (2015)

BACKGROUND:Defective cellular transport processes can lead to aberrant accumulation of trace elements, iron, small molecules and hormones in the cell, which in turn may promote the formation of reactive oxygen species, promoting DNA damage and aberra

Externí odkaz: https://doaj.org/article/74fe8007d1a04d919ac1e8b4f777c5b7

Menstrual pain and risk of epithelial ovarian cancer: Results from the Ovarian Cancer Association Consortium

Autor: Anna H. Wu, Daniel W. Cramer, Francesmary Modugno, Ana Babic, Linda J. Titus, Harvey A. Risch, Marc T. Goodman, Susan J. Jordan, Holly R. Harris, Andrew Berchuck, Penelope M. Webb, Allison F. Vitonis, Mary Anne Rossing, Kathryn L. Terry, Joellen M. Schildkraut, Susanne K. Kjaer, Kirsten B. Moysich, Celeste Leigh Pearce, Kristine G. Wicklund, Jennifer A. Doherty, Roberta B. Ness

Publikováno v: Int J Cancer

Menstrual pain, a common gynecological condition, has been associated with increased risk of ovarian cancer in some, but not all studies. Furthermore, potential variations in the association between menstrual pain and ovarian cancer by histologic sub

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https://doi.org/10.1002/ijc.31010

Chronic Recreational Physical Inactivity and Epithelial Ovarian Cancer Risk: Evidence from the Ovarian Cancer Association Consortium

Autor: Andrew Berchuck, Nicolas Wentzensen, Jennifer A. Doherty, Brooke L. Fridley, Albina N. Minlikeeva, Daniel W. Cramer, J. Brian Szender, Mary Anne Rossing, Chi Chen Hong, Anna H. Wu, Stacey J. Winham, Estrid Høgdall, Barbara Schmalfeldt, Elizabeth A. Szamreta, Marc T. Goodman, Robert P. Edwards, Joellen M. Schildkraut, Allan Jensen, Rikki Cannioto, Chiu-Chen Tseng, Harvey A. Risch, Jenny Chang-Claude, Celeste Leigh Pearce, Robert A. Vierkant, Kristine G. Wicklund, Michael J. LaMonte, Satoyo Hosono, Penelope M. Webb, Keitaro Matsuo, Francesmary Modugno, Susanne K. Kjaer, R Klapdor, Ellen L. Goode, Pamela J. Thompson, Kirsten B. Moysich, Emily Gower, Roberta B. Ness, Kathryn L. Terry, Linda E. Kelemen, Kevin H. Eng, Elisa V. Bandera, Catherine M. Olsen, Sara H. Olson, Malcolm C. Pike, Susan J. Jordan, Gary Zirpoli, Lara E. Sucheston-Campbell

Publikováno v: Cancer Epidemiology, Biomarkers & Prevention. 25:1114-1124

Background: Despite a large body of literature evaluating the association between recreational physical activity and epithelial ovarian cancer (EOC) risk, the extant evidence is inconclusive, and little is known about the independent association betw

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fb7eb81db5584167c5c033fd79369ed
https://doi.org/10.1158/1055-9965.epi-15-1330