Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Kristine A. Gordon"'
Autor:
Scott C. Jeffrey, Robert P. Lyon, Peter D. Senter, Ivan J. Stone, Weiping Zeng, Kim K. Emmerton, Brian E. Toki, Kristine A. Gordon, Andrew B. Waight, Julia H. Cochran, Joshua H. Hunter, Jocelyn R. Setter, Thomas A. Pires, Joseph Z. Hamilton, Patrick J. Burke
A quaternary ammonium-based drug-linker has been developed to expand the scope of antibody–drug conjugate (ADC) payloads to include tertiary amines, a functional group commonly present in biologically active compounds. The linker strategy was exemp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01277dcf190fe027b1aa165ef0569aff
https://doi.org/10.1158/1535-7163.c.6538699.v1
https://doi.org/10.1158/1535-7163.c.6538699.v1
Autor:
Scott C. Jeffrey, Robert P. Lyon, Peter D. Senter, Ivan J. Stone, Weiping Zeng, Kim K. Emmerton, Brian E. Toki, Kristine A. Gordon, Andrew B. Waight, Julia H. Cochran, Joshua H. Hunter, Jocelyn R. Setter, Thomas A. Pires, Joseph Z. Hamilton, Patrick J. Burke
Plasma stability of quaternary ammonium linker in rodent plasma.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af650b3133fc7e21796e5772ffd33361
https://doi.org/10.1158/1535-7163.22507474
https://doi.org/10.1158/1535-7163.22507474
Autor:
Scott C. Jeffrey, Robert P. Lyon, Peter D. Senter, Ivan J. Stone, Weiping Zeng, Kim K. Emmerton, Brian E. Toki, Kristine A. Gordon, Andrew B. Waight, Julia H. Cochran, Joshua H. Hunter, Jocelyn R. Setter, Thomas A. Pires, Joseph Z. Hamilton, Patrick J. Burke
Pharmacokinetic profile of clearance for three ADCs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f40a60bf104249e877111afed1bfdb6
https://doi.org/10.1158/1535-7163.22507471
https://doi.org/10.1158/1535-7163.22507471
Autor:
Scott C. Jeffrey, Robert P. Lyon, Peter D. Senter, Ivan J. Stone, Weiping Zeng, Kim K. Emmerton, Brian E. Toki, Kristine A. Gordon, Andrew B. Waight, Julia H. Cochran, Joshua H. Hunter, Jocelyn R. Setter, Thomas A. Pires, Joseph Z. Hamilton, Patrick J. Burke
Experimental details for the chemical synthesis of the drug-linkers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09b83380d151e3b1739d6b2739f97589
https://doi.org/10.1158/1535-7163.22507477.v1
https://doi.org/10.1158/1535-7163.22507477.v1
Autor:
Che-Leung Law, Iqbal S. Grewal, Paul J. Carter, Tamar E. Boursalian, Maureen Ryan, Steven Duniho, Carol A. Morris-Tilden, Kristine A. Gordon, Kerry Klussman, Charlotte F. McDonagh, Leia M. Smith, Julie A. McEarchern
Supplemental data Figure 2 from Preclinical Characterization of SGN-70, a Humanized Antibody Directed against CD70
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73b0f02df417d29d3cdfdf216f7260c6
https://doi.org/10.1158/1078-0432.22439359.v1
https://doi.org/10.1158/1078-0432.22439359.v1
Autor:
Che-Leung Law, Iqbal S. Grewal, Paul J. Carter, Tamar E. Boursalian, Maureen Ryan, Steven Duniho, Carol A. Morris-Tilden, Kristine A. Gordon, Kerry Klussman, Charlotte F. McDonagh, Leia M. Smith, Julie A. McEarchern
Supplementary Table 1. CD70 and CD27 expression on hematologic tumor cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::422ad6c281bb23a2464a5e1982dbaa5f
https://doi.org/10.1158/1078-0432.22439347.v1
https://doi.org/10.1158/1078-0432.22439347.v1
Autor:
Che-Leung Law, Iqbal S. Grewal, Paul J. Carter, Tamar E. Boursalian, Maureen Ryan, Steven Duniho, Carol A. Morris-Tilden, Kristine A. Gordon, Kerry Klussman, Charlotte F. McDonagh, Leia M. Smith, Julie A. McEarchern
Supplemental data Figure 4 from Preclinical Characterization of SGN-70, a Humanized Antibody Directed against CD70
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d62a8e4e98822cb29c03d0ff7220a2c0
https://doi.org/10.1158/1078-0432.22439353.v1
https://doi.org/10.1158/1078-0432.22439353.v1
Autor:
Che-Leung Law, Iqbal S. Grewal, Paul J. Carter, Tamar E. Boursalian, Maureen Ryan, Steven Duniho, Carol A. Morris-Tilden, Kristine A. Gordon, Kerry Klussman, Charlotte F. McDonagh, Leia M. Smith, Julie A. McEarchern
Supplemental data Figure 3 from Preclinical Characterization of SGN-70, a Humanized Antibody Directed against CD70
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68c4895dccd1ff616961ea091109f37d
https://doi.org/10.1158/1078-0432.22439356.v1
https://doi.org/10.1158/1078-0432.22439356.v1
Autor:
Che-Leung Law, Iqbal S. Grewal, Paul J. Carter, Tamar E. Boursalian, Maureen Ryan, Steven Duniho, Carol A. Morris-Tilden, Kristine A. Gordon, Kerry Klussman, Charlotte F. McDonagh, Leia M. Smith, Julie A. McEarchern
Supplementary Figures S1-S4 from Preclinical Characterization of SGN-70, a Humanized Antibody Directed against CD70
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1149f1efa8dae2589ffaacd68aa0d7ca
https://doi.org/10.1158/1078-0432.22439350.v1
https://doi.org/10.1158/1078-0432.22439350.v1
Autor:
Che-Leung Law, Iqbal S. Grewal, Paul J. Carter, Tamar E. Boursalian, Maureen Ryan, Steven Duniho, Carol A. Morris-Tilden, Kristine A. Gordon, Kerry Klussman, Charlotte F. McDonagh, Leia M. Smith, Julie A. McEarchern
Supplemental data Figure 1 from Preclinical Characterization of SGN-70, a Humanized Antibody Directed against CD70
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44ba638b7c8872f188154eaef3b46b07
https://doi.org/10.1158/1078-0432.22439365
https://doi.org/10.1158/1078-0432.22439365