Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kristina Zumer"'
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 5, p e1012059 (2024)
The eukaryotic mRNA life cycle includes transcription, nuclear mRNA export and degradation. To quantify all these processes simultaneously, we perform thiol-linked alkylation after metabolic labeling of RNA with 4-thiouridine (4sU), followed by seque
Externí odkaz:
https://doaj.org/article/ec8b7f1a85204c198523b4d4d47910ce
Autor:
Srinivasan Rengachari, Sandra Schilbach, Thangavelu Kaliyappan, Jerome Gouge, Kristina Zumer, Juliane Schwarz, Henning Urlaub, Christian Dienemann, Alessandro Vannini, Patrick Cramer
Publikováno v:
Nature structural & molecular biology.
Nature Structural and Molecular Biology
Nature Structural and Molecular Biology
RNA polymerase II (Pol II) carries out transcription of both protein-coding and non-coding genes. Whereas Pol II initiation at protein-coding genes has been studied in detail, Pol II initiation at non-coding genes, such as small nuclear RNA (snRNA) g
The eukaryotic mRNA life cycle includes transcription, nuclear mRNA export and degradation. To quantify all these processes simultaneously, we perform thiol-linked alkylation after metabolic labeling of RNA with 4-thiouridine (4sU), followed by seque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acd33f85cfc12144a8661c3368a6bc13
https://doi.org/10.1101/2023.05.04.539375
https://doi.org/10.1101/2023.05.04.539375
Publikováno v:
The Journal of Immunology. 190:2479-2482
The autoimmune regulator is a critical transcription factor for generating central tolerance in the thymus. Recent studies have revealed how the autoimmune regulator targets many otherwise tissue-restricted Ag genes to enable negative selection of au
Publikováno v:
The Journal of biological chemistry, vol 291, iss 34
Journal of Biological Chemistry
Journal of Biological Chemistry
The autoimmune regulator (AIRE) is a transcription factor which is expressed in medullary thymic epithelial cells. It directs the expression of otherwise tissue-specific antigens, which leads to the elimination of autoreactive T cells during developm