Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Kristina Wolf"'
Publikováno v:
Resilient Cities and Structures, Vol 2, Iss 2, Pp 24-41 (2023)
Extreme weather conditions can adversely impact transport networks and driver behaviour, leading to variations in traffic volumes and travel times and increased accident rates. Emergency services that need to navigate to an accident site in the short
Externí odkaz:
https://doaj.org/article/8bec2dd191bf44d6acba90005458c3cc
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Cost-effective on-demand computing resources can help to process the increasing number of large, diverse datasets generated from smart internet-enabled technology, such as sensors, CCTV cameras, and mobile devices, with high temporal resolut
Externí odkaz:
https://doaj.org/article/d16fb16ce9064e1d9e46603d336514d7
Publikováno v:
California Agriculture, Vol 71, Iss 03, Pp 120-124 (2017)
California's Mediterranean agro-ecosystems are a major source of U.S. fruits and vegetables, and vulnerable to future extremes of precipitation and temperature brought on by climate change, including increased drought and flooding, and more intense a
Externí odkaz:
https://doaj.org/article/2d42a698cc554ac296939314a76ae669
Publikováno v:
Clinical oral investigations. 24(5)
The aims of this retrospective longitudinal study were to present the incidence of external apical root resorption (EARR) in the maxillary anterior teeth of patients with complete unilateral cleft lip and palate (CUCLP) and to evaluate the influence
Autor:
Daniel Vitt, Kristina Wolf, Roland Baumgartner, Nobumitsu Tajima, Tokuyuki Yamashita, Viola Trentinaglia, Marcus Blisse, Andrea Aschenbrenner, Tanja Wieber, Martin Lang, Markus H.J. Seifert, Hitoshi Noda
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:5417-5422
We report on a hit generation and hit-to-lead program of a novel class of glucokinase activators (GKAs). Hit compounds, activators at low glucose concentration only were identified by vHTS. Scaffold modification reliably afforded activators also at h
Autor:
Kristina Wolf, Jan Mies, Johann Leban, Markus H.J. Seifert, Sandra Rath, Viola Trentinaglia, Marcel Baierl, Astrid Gotschlich, Kerstin Kronthaler
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:5858-5862
A novel class of NF-kappaB pathway signaling inhibitors was discovered by virtual screening, medicinal chemistry, and QSAR analysis. An initial set of compounds inhibited NF-kappaB signaling in a whole cell reporter gene assay in the micro-molar rang
Publikováno v:
Information Systems Journal. 14:295-309
This paper presents an evaluation of Supply Chain Management Soft- ware. For this purpose, we conducted an empirical study in the European auto- motive industry among car manufacturers, suppliers, distributors, and logistic service providers from 25
Publikováno v:
BIOSILICO. 1:143-149
In silico methods may benefit drug discovery and development significantly by saving an average of $130 million and 0.8 years per drug. Virtual high-throughput screening (vHTS) applies in silico approaches, such as docking and alignment, to large vir
Autor:
Kristina Wolf, Matthias Dormeyer
Publikováno v:
Parasitology Research. 90:S91-S96
The discovery and optimization of antiparasitic compounds has profited by information-based methods newly emerged in the modern drug development process. The generation of computer models enables the cost-efficient and fast computational screening of
Autor:
Kim Messer, Reto Brun, Jörg Mühlbacher, Gerhard Bringmann, Adriaan M. Louis, Matthias Grüne, Kristina Wolf
Publikováno v:
Phytochemistry. 60:389-397
The isolation and structural elucidation of dioncophylline E, a novel naphthylisoquinoline alkaloid from the rare West African liana Dioncophyllum thollonii, is described. The alkaloid displays an unusual 7,3'-linkage between the naphthalene and the