Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Kristina Wehr"'
Publikováno v:
Genetics. 205:1215-1228
Drosophila females are larger than males. In this article, we describe how X-chromosome dosage drives sexual dimorphism of body size... Drosophila females are larger than males. In this article, we describe how X-chromosome dosage drives sexual dimor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30ca8662a2ae6c4f6e7abe77412287a4
https://doi.org/10.1534/genetics.116.192260
https://doi.org/10.1534/genetics.116.192260
Publikováno v:
Genetics
Drosophila females are larger than males. In this article, we describe how X-chromosome dosage drives sexual dimorphism of body size through two means: first, through unbalanced expression of a key X-linked growth-regulating gene, and second, through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d093a171f93a7b0a538a5624dbfb3ab5
https://pubmed.ncbi.nlm.nih.gov/28064166
https://pubmed.ncbi.nlm.nih.gov/28064166
Publikováno v:
Developmental Cell. 12:851-862
RNAi is a widespread mechanism by which organisms regulate gene expression and defend their genomes against viruses and transposable elements. Here we report the identification of Drosophila zucchini (zuc) and squash (squ), which function in germline
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::082cd7231c77a3c69c3ed1c55ec124d2
https://doi.org/10.1016/j.devcel.2007.03.022
https://doi.org/10.1016/j.devcel.2007.03.022
Publikováno v:
Biological Sciences Publications
The deadlock gene is required for a number of key developmental events in Drosophila oogenesis. Females homozygous for mutations in the deadlock gene lay few eggs and those exhibit severe patterning defects along both the anterior–posterior and dor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b4b2a1108e16c1f915354ab85600fa6
https://doi.org/10.1016/j.ydbio.2006.03.002
https://doi.org/10.1016/j.ydbio.2006.03.002
Autor:
Andreas Rolfs, Tim J Peters, Karen Brennan, Adrian Bomford, Paola Marciani, Farzin Farzaneh, Matthias W. Hentze, Silvia Miret, Robert J. Simpson, Dalna Barrow, Andrew T. McKie, Kristina Wehr, Matthias A. Hediger
Publikováno v:
Scopus-Elsevier
Iron absorption by the duodenal mucosa is initiated by uptake of ferrous Fe(II) iron across the brush border membrane and culminates in transfer of the metal across the basolateral membrane to the portal vein circulation by an unknown mechanism. We d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3cc5811e5c34e57ce3302959c2fd723
Publikováno v:
Genes & Development. 13:864-876
Heterogeneous nuclear RNA-binding proteins, hnRNPs, have been implicated in nuclear export of mRNAs in organisms from yeast to humans. A germ-line mutation in a Drosophila hnRNP, Squid (Sqd)/hrp40, causes female sterility as a result of mislocalizati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44f1ceb961202f0fbb35cfe7f0469d04
https://doi.org/10.1101/gad.13.7.864
https://doi.org/10.1101/gad.13.7.864
Publikováno v:
EMBL-EBI
Iron regulatory protein 1 (IRP-1) binding to an iron-responsive element (IRE) located close to the cap structure of mRNAs represses translation by precluding the recruitment of the small ribosomal subunit to these mRNAs. This mechanism is position de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4217beeacccd604f9346a0a0f3f091b
https://doi.org/10.1128/mcb.19.1.807
https://doi.org/10.1128/mcb.19.1.807
Autor:
Matthias W. Hentze, Andrea Deters, Kristina Wehr, Christian Hagemeier, Gabriele Neu-Yilik, Andreas E. Kulozik, Ute Frede, Rolf Thermann
Publikováno v:
The EMBO Journal. 17:3484-3494
Premature translation termination codons resulting from nonsense or frameshift mutations are common causes of genetic disorders. Complications arising from the synthesis of C-terminally truncated polypeptides can be avoided by 'nonsense-mediated deca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52d3b67aa670a861dae3903109504e2c
https://doi.org/10.1093/emboj/17.12.3484
https://doi.org/10.1093/emboj/17.12.3484
Autor:
James R. Connor, Mark A. Smith, Kristina Wehr, Peggy L.R. Harris, Sandra L. Siedlak, George Perry
Publikováno v:
Brain Research. 788:232-236
A role for altered iron metabolism in the pathogenesis of Alzheimer's disease has been suggested by several reports associating the cardinal neuropathologic lesions with markers of free radical-induced damage and redox-active iron. We hypothesized th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b31161ebf8b05b63d579fdd8c1f9e3d4
https://doi.org/10.1016/s0006-8993(98)00002-x
https://doi.org/10.1016/s0006-8993(98)00002-x