Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Kristina W. Thiel"'
Autor:
Dario Ruiz-Ciancio, Suresh Veeramani, Rahul Singh, Eric Embree, Chris Ortman, Kristina W. Thiel, William H. Thiel
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 4, Pp 102358- (2024)
Aptamers are short single-stranded DNA or RNA molecules with high affinity and specificity for targets and are generated using the iterative systematic evolution of ligands by exponential enrichment (SELEX) process. Next-generation sequencing (NGS) r
Externí odkaz:
https://doaj.org/article/cc384644dd5d4f4c99c131eb63f2311c
Autor:
Craig M. Rush, Zannel Blanchard, Jacob T. Polaski, Kyle S. Osborne, Krystle Osby, Jeffery M. Vahrenkamp, Chieh-Hsiang Yang, David H. Lum, Christy R. Hagan, Kimberly K. Leslie, Miles A. Pufall, Kristina W. Thiel, Jason Gertz
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Most endometrial cancers express the hormone receptor estrogen receptor alpha (ER) and are driven by excess estrogen signaling. However, evaluation of the estrogen response in endometrial cancer cells has been limited by the availability of
Externí odkaz:
https://doaj.org/article/aac81ba3c33c4f1da08291f62bda8d89
Autor:
Jianling Bi, Yuping Zhang, Paige K. Malmrose, Haley A. Losh, Andreea M. Newtson, Eric J. Devor, Kristina W. Thiel, Kimberly K. Leslie
Publikováno v:
Cell Death and Disease, Vol 13, Iss 1, Pp 1-10 (2022)
Abstract Histone deacetylase (HDAC) inhibitors and proteasome inhibitors have been approved by the FDA for the treatment of multiple myeloma and lymphoma, respectively, but have not achieved similar activity as single agents in solid tumors. Preclini
Externí odkaz:
https://doaj.org/article/22755d59f786409eb791c68e2d8e5ad7
Autor:
Jesus Gonzalez Bosquet, Eric J. Devor, Andreea M. Newtson, Brian J. Smith, David P. Bender, Michael J. Goodheart, Megan E. McDonald, Terry A. Braun, Kristina W. Thiel, Kimberly K. Leslie
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Nearly a third of patients with high-grade serous ovarian cancer (HGSC) do not respond to initial therapy and have an overall poor prognosis. However, there are no validated tools that accurately predict which patients will not respond. Our
Externí odkaz:
https://doaj.org/article/f68931067a254b7db52a837c8291c2da
Autor:
Jianling Bi, Garima Dixit, Yuping Zhang, Eric J. Devor, Haley A. Losh, Andreea M. Newtson, Kristen L. Coleman, Donna A. Santillan, Thorsten Maretzky, Kristina W. Thiel, Kimberly K. Leslie
Publikováno v:
Pharmaceuticals, Vol 14, Iss 7, p 682 (2021)
Angiogenesis plays a crucial role in tumor development and metastasis. Both bevacizumab and cediranib have demonstrated activity as single anti-angiogenic agents in endometrial cancer, though subsequent studies of bevacizumab combined with chemothera
Externí odkaz:
https://doaj.org/article/b00a64b6198e48c4b43780cdc49369ac
Autor:
Adriann M. Hovey, Eric J. Devor, Patrick J. Breheny, Sarah L. Mott, Donghai Dai, Kristina W. Thiel, Kimberly K. Leslie
Publikováno v:
Translational Oncology, Vol 8, Iss 2, Pp 85-96 (2015)
Cancer-testis (CT) antigens are a large family of genes that are selectively expressed in human testis germ cells, overexpressed in a variety of tumors and predominantly located on the X chromosome. To date, all known CT antigens are protein-coding g
Externí odkaz:
https://doaj.org/article/ed54ef008e0d4b50b271743fed8ca0e2
Autor:
Xiangbing Meng, Don S. Dizon, Shujie Yang, Xinjun Wang, Danlin Zhu, Kristina W. Thiel, Kimberly K. Leslie
Publikováno v:
Obstetrics and Gynecology International, Vol 2013 (2013)
Externí odkaz:
https://doaj.org/article/fa1ca3b54f4546c09fa225d3f5b99cf2
Autor:
Kimberly K. Leslie, Kristina W. Thiel, Henry D. Reyes, Shujie Yang, Yuping Zhang, Matthew J. Carlson, Nirmala S. Kumar, Donghai D. Dai
Publikováno v:
Obstetrics and Gynecology International, Vol 2013 (2013)
Endometrial cancer, the most common gynecologic malignancy in the United States, is on the rise, and survival is worse today than 40 years ago. In order to improve the outcomes, better biomarkers that direct the choice of therapy are urgently needed.
Externí odkaz:
https://doaj.org/article/480d5f652acb498ca880c718efc99538
Autor:
Kristina W. Thiel, Eric J. Devor, Virginia L. Filiaci, David Mutch, Katherine Moxley, Angeles Alvarez Secord, Krishnansu S. Tewari, Megan E. McDonald, Cara Mathews, Casey Cosgrove, Summer Dewdney, Carol Aghajanian, Megan I. Samuelson, Heather A. Lankes, Robert A. Soslow, Kimberly K. Leslie
Publikováno v:
Journal of Clinical Oncology. 40:3289-3300
PURPOSE The status of p53 in a tumor can be inferred by next-generation sequencing (NGS) or by immunohistochemistry (IHC). We examined the association between p53 IHC and sequence and whether p53 IHC alone, or integrated with TP53 NGS, predicts the o
Autor:
Craig M. Rush, Zannel Blanchard, Jacob T. Polaski, Kyle S. Osborne, Krystle Osby, Jeffery M. Vahrenkamp, Chieh-Hsiang Yang, David H. Lum, Christy R. Hagan, Kimberly K. Leslie, Miles A. Pufall, Kristina W. Thiel, Jason Gertz
Most endometrial cancers express the hormone receptor estrogen receptor alpha (ER) and are driven by excess estrogen signaling. However, evaluation of the estrogen response in endometrial cancer cells has been limited by the availability of hormonall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fb88fa8c99e067df976fd979d617c88
https://doi.org/10.1101/2022.08.25.505203
https://doi.org/10.1101/2022.08.25.505203