Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kristina Ushakova"'
Autor:
Victor Shamanskiy, Alina A. Mikhailova, Evgenii O. Tretiakov, Kristina Ushakova, Alina G. Mikhailova, Sergei Oreshkov, Dmitry A. Knorre, Natalia Ree, Jonathan B. Overdevest, Samuel W. Lukowski, Irina Gostimskaya, Valerian Yurov, Chia-Wei Liou, Tsu-Kung Lin, Wolfram S. Kunz, Alexandre Reymond, Ilya Mazunin, Georgii A. Bazykin, Jacques Fellay, Masashi Tanaka, Konstantin Khrapko, Konstantin Gunbin, Konstantin Popadin
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Background Aging in postmitotic tissues is associated with clonal expansion of somatic mitochondrial deletions, the origin of which is not well understood. Such deletions are often flanked by direct nucleotide repeats, but this alone does no
Externí odkaz:
https://doaj.org/article/4165b20a8937424aafa2ba2a950a3360
Autor:
Alina G Mikhailova, Alina A Mikhailova, Kristina Ushakova, Evgeny O Tretiakov, Dmitrii Iliushchenko, Victor Shamansky, Valeria Lobanova, Ivan Kozenkov, Bogdan Efimenko, Andrey A Yurchenko, Elena Kozenkova, Evgeny M Zdobnov, Vsevolod Makeev, Valerian Yurov, Masashi Tanaka, Irina Gostimskaya, Zoe Fleischmann, Sofia Annis, Melissa Franco, Kevin Wasko, Stepan Denisov, Wolfram S Kunz, Dmitry Knorre, Ilya Mazunin, Sergey Nikolaev, Jacques Fellay, Alexandre Reymond, Konstantin Khrapko, Konstantin Gunbin, Konstantin Popadin
Publikováno v:
Denisov, S 2022, ' A mitochondria-specific mutational signature of aging: increased rate of A > G substitutions on the heavy strand ', Nucleic acids research, vol. 50, pp. 10264–10277 . https://doi.org/10.1093/nar/gkac779
The mutational spectrum of the mitochondrial DNA (mtDNA) does not resemble any of the known mutational signatures of the nuclear genome and variation in mtDNA mutational spectra between different organisms is still incomprehensible. Since mitochondri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aaf04f68180d9afc181527a26230b3c
https://doi.org/10.1093/nar/gkac779
https://doi.org/10.1093/nar/gkac779
Autor:
Kristina Ushakova, Stepan Denisov, Wolfram S. Kunz, Leonard V. Polishchuk, Konstantin Khrapko, Aleksandr Kuzmin, Dmitry A. Knorre, I. O. Mazunin, Ivan Kozenkov, Alexander Kuptsov, Evgenii O. Tretiakov, Alina G. Mikhailova, Konstantin Popadin, Vsevolod J. Makeev, Viktor A. Shamanskiy, Jacques Fellay, Rita Castilho, Sergey Oreshkov, Dylan Lawless, Alina A. Mihailova, Dmitrii Iliushchenko, V. A. Yurov, Konstantin V. Gunbin, Masashi Tanaka
The variation in the mutational spectrum of the mitochondrial genome (mtDNA) among species is not well understood. Recently, we demonstrated an increase in A>G substitutions on a heavy chain (hereafter AH>GH) of mtDNA in aged mammals, interpreting it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b289e0d13227770f00e24111701861c3
https://doi.org/10.1101/2020.07.25.221184
https://doi.org/10.1101/2020.07.25.221184
Autor:
Victor Shamanskiy, Alina A. Mikhailova, Kristina Ushakova, Alina G. Mikhailova, Sergei Oreshkov, Dmitry Knorre, Evgenii O. Tretiakov, Natalia Ri, Jonathan B. Overdevest, Samuel W. Lukowski, Irina Gostimskaya, Valerian Yurov, Chia-Wei Liou, Tsu-Kung Lin, Wolfram S. Kunz, Alexandre Reymond, Ilya Mazunin, Georgii A. Bazykin, Konstantin Gunbin, Jacques Fellay, Masashi Tanaka, Konstantin Khrapko, Konstantin Popadin
Aging in postmitotic tissues is associated with clonal expansion of somatic mitochondrial deletions, the origin of which is not well understood. Deletions in mitochondrial DNA (mtDNA) are often flanked by direct nucleotide repeats, but this alone doe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b7b41d63cb530114b932e2ac1ae70e6
https://doi.org/10.1101/603282
https://doi.org/10.1101/603282