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Autor:
Kristina Roucova, Denisa Jansova, Tomáš Mašek, Rajan Iyyappan, Edgar Del Llano, Martin Pospíšek, Anna Jindrova, Marketa Koncicka, Andrej Susor, Lenka Gahurova, Alexander W. Bruce, Michal Kubelka
Publikováno v:
Aging Cell
Increasing maternal age in mammals is associated with poorer oocyte quality, involving higher aneuploidy rates and decreased developmental competence. Prior to resumption of meiosis, fully developed mammalian oocytes become transcriptionally silent u