Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kristina McAinsh"'
Autor:
I. Lorena Arancibia-Carcamo, Katharine R. Smith, Zhen Yan, Josef T. Kittler, Volker Haucke, Stephen J. Moss, Kristina McAinsh, Guojun Chen
Publikováno v:
Neuropharmacology. 55:844-850
The number of surface and synaptic GABAA receptors is an important determinant of inhibitory synapse strength. Surface receptor number is in part controlled by removal of receptors from the membrane by interaction with the clathrin adaptor AP2. Here
Autor:
Kristina McAinsh, Josef T. Kittler, Volker Haucke, Guojun Chen, Stephen J. Moss, Yury D. Bogdanov, Stephan Honing, Jasmina N. Jovanovic, I. Lorena Arancibia-Carcamo, Zhen Yan, Menelas N. Pangalos
Publikováno v:
Proceedings of the National Academy of Sciences. 102:14871-14876
The efficacy of synaptic inhibition depends on the number of γ-aminobutyric acid type A receptors (GABA A Rs) expressed on the cell surface of neurons. The clathrin adaptor protein 2 (AP2) complex is a critical regulator of GABA A R endocytosis and,
Publikováno v:
Molecular Neurobiology. 26:251-268
Fast synaptic inhibition in the brain is largely mediated by ionotropic GABA receptors, which can be subdivided into GABAA and GABAC receptors based on pharmacological and molecular criteria. GABAA receptors are important therapeutic targets for a ra
Autor:
Verena Tretter, Guojun Chen, Kristina McAinsh, I. Lorena Arancibia-Carcamo, Viktoria Kukhtina, Katharine R. Smith, Stephen J. Moss, Zhenglin Gu, Wolfram Saenger, Ardeschir Vahedi-Faridi, Josef T. Kittler, Volker Haucke, Zhen Yan
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 105(9)
The regulation of the number of γ2-subunit-containing GABA A receptors (GABA A Rs) present at synapses is critical for correct synaptic inhibition and animal behavior. This regulation occurs, in part, by the controlled removal of receptors from the