Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kristina M. Estok"'
Autor:
Christopher H. van Dyck, Erin B. Frohlich, Effie M. Mitsis, Frederic Bois, Kristina M. Estok, Julie K. Staley, Kelly P. Cosgrove, Gilles Tamagnan, John Seibyl
Publikováno v:
Neurobiology of Aging. 30:1490-1497
Human postmortem studies have reported decreases with age in high affinity nicotine binding in brain. We investigated the effect of age on β 2 -containing nicotinic acetylcholine receptor (β 2 -nAChR) availability in eight brain regions of living h
Autor:
Gilles Tamagnan, Ronald M. Baldwin, Lekshmi Santhosh, Kristina M. Estok, Christopher H. van Dyck, Effie M. Mitsis, Martha G. MacAvoy, Rebecca S. Vogel, Julie K. Staley
Publikováno v:
Psychiatry Research: Neuroimaging. 173:212-217
Postmortem studies show reductions in brain serotonin 2A (5-HT(2A)) receptors in Alzheimer's disease (AD). Converging evidence also suggests that serotonergic dysregulation may contribute to behavioral symptoms that frequently occur in AD. This study
Autor:
Effie M. Mitsis, John Seibyl, Erin B. Frohlich, Julie K. Staley, Frederic Bois, Christopher H. van Dyck, Kelly P. Cosgrove, Kristina M. Estok, Gilles Tamagnan
Publikováno v:
Annals of the New York Academy of Sciences. 1097
Human postmortem studies have reported decreases with age in high-affinity nicotine binding in brain. We have been investigating in vivo the availability of the beta(2)-containing nicotinic acetylcholine receptor (beta(2)-nAChR) in healthy nonsmokers
Autor:
Erin B. Frohlich, Suchitra Krishnan-Sarin, Kristina M. Estok, Kelly P. Cosgrove, Stephanie S. O'Malley, Erica Krantzler, Ronald M. Baldwin, Joel A. Dubin, Edythe D. London, Peter Jatlow, Julie K. Staley, Christopher H. van Dyck, Gilles Tamagnan, Edward Perry, Eric Brenner, Marina R. Picciotto, John Seibyl
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 26(34)
Nicotine, the addictive chemical in tobacco smoke, initiates its actions in brain through nicotinic acetylcholine receptors (nAChRs). In particular, nAChRs containing β2-subunits (β2*-nAChRs) the most prevalent subtype, mediate the reinforcing prop