Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kristina M, Boguslawski"'
Autor:
Ashira Lubkin, Lucie Bernard-Raichon, Ashley L. DuMont, Ana Mayela Valero Jimenez, Gregory G. Putzel, Juan Gago, Erin E. Zwack, Olufolakemi Olusanya, Kristina M. Boguslawski, Simone Dallari, Sophie Dyzenhaus, Christin Herrmann, Juliana K. Ilmain, Georgia L. Isom, Miranda Pawline, Andrew I. Perault, Sofya Perelman, William E. Sause, Ifrah Shahi, Amelia St. John, Rebecca Tierce, Xuhui Zheng, Chunyi Zhou, Maria G. Noval, Anna O'Keeffe, Magda Podkowik, Sandra Gonzales, Kenneth Inglima, Ludovic Desvignes, Sarah E. Hochman, Kenneth A. Stapleford, Lorna E. Thorpe, Alejandro Pironti, Bo Shopsin, Ken Cadwell, Meike Dittmann, Victor J. Torres
Publikováno v:
mBio, Vol 15, Iss 8 (2024)
ABSTRACT Severe COVID-19 has been associated with coinfections with bacterial and fungal pathogens. Notably, patients with COVID-19 who develop Staphylococcus aureus bacteremia exhibit higher rates of mortality than those infected with either pathoge
Externí odkaz:
https://doaj.org/article/623845162cdd4f2baf78452f589aa583
Autor:
Victor J. Torres, Kristina M. Boguslawski, Sofya S. Perelman, Nikollaq Vozhilla, Damian C. Ekiert, Ahmed M Moustafa, Adil Mohamed, Kayan Tam, David B. A. James, Rachel A Prescott, Bo Shopsin, Rita Chan, Chase W. Nelson, Apurva Narechania, Miranda B Pawline, Sang Yong Kim, Erin E Zwack, Meike Dittmann, Paul J. Planet, Juliana K Ilmain, Gira Bhabha, Sergei B. Koralov
Publikováno v:
Nature microbiology
Staphylococcus aureus have evolved into diverse lineages, known as clonal complexes (“CC”), which exhibit differences in the coding sequences of core virulence factors. Whether these alterations impact functionality is poorly understood. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::419204a9b82b34a83b448f3aa623a02c
http://europepmc.org/articles/PMC8597016
http://europepmc.org/articles/PMC8597016
Autor:
Christophe Langouët-Astrié, Kaori Oshima, Sarah A. McMurtry, Yimu Yang, Jakub M. Kwiecinski, Wells B. LaRivière, Jeffrey S. Kavanaugh, Igor Zakharevich, Kirk C. Hansen, Deling Shi, Fuming Zhang, Kristina M. Boguslawski, Sofya S. Perelman, Gouwei Su, Victor J. Torres, Jian Liu, Alexander R. Horswill, Eric P. Schmidt
Publikováno v:
Cell reports. 41(9)
Influenza infection is substantially worsened by the onset of secondary pneumonia caused by bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA). The bidirectional interaction between the influenza-injured lung microenvironment and MR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c76a3ec94ba78c8f0f826b3cebf8fa0
https://pubmed.ncbi.nlm.nih.gov/36450248
https://pubmed.ncbi.nlm.nih.gov/36450248
Autor:
Bostjan Kobe, Victor J. Torres, Adrienne W. Paton, Thomas Haselhorst, James C. Paton, Josephine F. Reijneveld, Arun V. Everest-Dass, Kristina M. Boguslawski, David B. A. James, Victor Nizet, Michael P. Jennings, Mark von Itzstein, Stephan Brouwer, John M. Atack, Christine M. Gillen, Zhenyao Luo, Lucy K. Shewell, Freda E.-C. Jen, Mark J. Walker, Christopher J. Day
Publikováno v:
Science Advances
Eight major CDCs use glycans as cellular receptors to potentiate cytotoxicity and bind glycans and cholesterol independently.
Cholesterol-dependent cytolysins (CDCs) form pores in cholesterol-rich membranes, but cholesterol alone is insufficient
Cholesterol-dependent cytolysins (CDCs) form pores in cholesterol-rich membranes, but cholesterol alone is insufficient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b81e76ae5e133f080ec6709c21223162
https://doi.org/10.1126/sciadv.aaz4926
https://doi.org/10.1126/sciadv.aaz4926
Autor:
Alesia N. McKeown, Kwa-Sur Tam, Nikollaq Vozhilla, Victor J. Torres, Nels C. Elde, Sang Yong Kim, Keenan A. Lacey, Christopher J. Day, Michael P. Jennings, Sergei B. Koralov, Kristina M. Boguslawski
Publikováno v:
Science Advances
Overcoming the species specificity of the MRSA toxin LukAB with a novel mouse model establishes a role for LukAB in vivo.
Many pathogens produce virulence factors that are specific toward their natural host. Clinically relevant methicillin-resis
Many pathogens produce virulence factors that are specific toward their natural host. Clinically relevant methicillin-resis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a3e9437e9b1353a3379be4855e29816
http://europepmc.org/articles/PMC7065885
http://europepmc.org/articles/PMC7065885
Autor:
Meera Nagarsheth, Nurgun Kose, Gopal Sapparapu, James B. Wood, Victor J. Torres, Nicole E. Putnam, David B. A. James, James E. Crowe, Lauren S. Jones, Kristina M. Boguslawski, James E. Cassat, Clarence B. Creech, Isaac P. Thomsen
Publikováno v:
The Journal of Infectious Diseases. 215:1124-1131
The 2-component leukotoxin LukAB is critical for Staphylococcus aureus targeting and killing of human neutrophils ex vivo and is produced in the setting of human infection. We report 3 LukAB-specific human monoclonal antibodies (mAbs) with distinct m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1efce2cae420d5e282843deaee81f74
https://doi.org/10.1093/infdis/jix071
https://doi.org/10.1093/infdis/jix071
Identification of biologic agents to neutralize the bicomponent leukocidins of Staphylococcus aureus
Autor:
Jeffrey Fernandez, Anthony Simon Lynch, Rita Chan, William R. Strohl, Victor J. Torres, Angela Payne, William E. Sause, Aidan O’Malley, Ashira Lubkin, Brian Whitaker, Kristina M. Boguslawski, Francis Alonzo, Peter T. Buckley
Publikováno v:
Science Translational Medicine. 11
A key aspect underlying the severity of infections caused by Staphylococcus aureus is the abundance of virulence factors that the pathogen uses to thwart critical components of the human immune response. One such mechanism involves the destruction of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d85355373f693d9d3042f20dfa7a0515
https://doi.org/10.1126/scitranslmed.aat0882
https://doi.org/10.1126/scitranslmed.aat0882
Publikováno v:
Molecular Microbiology. 96:325-348
Bacillus subtilis and its closest relatives have multiple rap-phr quorum sensing gene pairs that coordinate a variety of physiological processes with population density. Extra-chromosomal rap-phr genes are also present on mobile genetic elements, yet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::918fd7dbbb4795cc3a3787bd30d6ce05
https://doi.org/10.1111/mmi.12939
https://doi.org/10.1111/mmi.12939
Publikováno v:
Molecular microbiology. 96(2)
Bacillus subtilis and its closest relatives have multiple rap-phr quorum sensing gene pairs that coordinate a variety of physiological processes with population density. Extra-chromosomal rap-phr genes are also present on mobile genetic elements, yet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ef02573a81803c83bd0fe2756480681a
https://pubmed.ncbi.nlm.nih.gov/25598361
https://pubmed.ncbi.nlm.nih.gov/25598361
Autor:
Cédric Badiou, Kristina M. Boguslawski, Victor J. Torres, Thomas Henry, Jos A. G. van Strijp, Yves Colin, Michael P. Jennings, Tamara Reyes-Robles, Caroline Le Van Kim, Christopher J. Day, Carla J C Gosselaar-de Haas, Sylvie Cochet, András N. Spaan, François Vandenesch, Kok P. M. van Kessel, Pauline Yoong
Publikováno v:
Cell Host and Microbe
Cell Host and Microbe, Elsevier, 2015, 18 (3), pp.363-370. ⟨10.1016/j.chom.2015.08.001⟩
Cell Host & Microbe, 18(3), 363. Cell Press
ResearcherID
Cell Host and Microbe, 2015, 18 (3), pp.363-370. ⟨10.1016/j.chom.2015.08.001⟩
Cell Host and Microbe, Elsevier, 2015, 18 (3), pp.363-370. ⟨10.1016/j.chom.2015.08.001⟩
Cell Host & Microbe, 18(3), 363. Cell Press
ResearcherID
Cell Host and Microbe, 2015, 18 (3), pp.363-370. ⟨10.1016/j.chom.2015.08.001⟩
Introduction: Staphylococcus aureus is a major human pathogen. Infections by this bacterium range from minor skin and soft tissue infections, to more invasive and life threating infections like sepsis, osteomyelitis, and pneumonia. In order to succes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa195d29cce8092f4afff291d61d00c3