Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Kristina Lorenzen"'
Autor:
Patrick Y. A. Reinke, Robin Schubert, Dominik Oberthür, Marina Galchenkova, Aida Rahmani Mashhour, Sebastian Günther, Anaïs Chretien, Adam Round, Brandon Charles Seychell, Brenna Norton-Baker, Chan Kim, Christina Schmidt, Faisal H. M. Koua, Alexandra Tolstikova, Wiebke Ewert, Gisel Esperanza Peña Murillo, Grant Mills, Henry Kirkwood, Hévila Brognaro, Huijong Han, Jayanath Koliyadu, Joachim Schulz, Johan Bielecki, Julia Lieske, Julia Maracke, Juraj Knoska, Kristina Lorenzen, Lea Brings, Marcin Sikorski, Marco Kloos, Mohammad Vakili, Patrik Vagovic, Philipp Middendorf, Raphael de Wijn, Richard Bean, Romain Letrun, Seonghyun Han, Sven Falke, Tian Geng, Tokushi Sato, Vasundara Srinivasan, Yoonhee Kim, Oleksandr M. Yefanov, Luca Gelisio, Tobias Beck, Andrew S. Doré, Adrian P. Mancuso, Christian Betzel, Saša Bajt, Lars Redecke, Henry N. Chapman, Alke Meents, Dušan Turk, Winfried Hinrichs, Thomas J. Lane
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract The main protease (Mpro) of SARS-CoV-2 is critical for viral function and a key drug target. Mpro is only active when reduced; turnover ceases upon oxidation but is restored by re-reduction. This suggests the system has evolved to survive pe
Externí odkaz:
https://doaj.org/article/7a737b71ae764265a7f11a3df650ea0b
Autor:
Maria Backhouse, Rosa Lehmann, Kristina Lorenzen, Malte Lühmann, Janina Puder, Fabricio Rodríguez, Anne Tittor
This open access book focuses on the meanings, agendas, as well as the local and global implications of bioeconomy and bioenergy policies in and across South America, Asia and Europe. It explores how a transition away from a fossil and towards a bio-
Autor:
Prabhu Rajaiah Prince, Janine Hochmair, Hévila Brognaro, Susanna Gevorgyan, Maximilian Franck, Robin Schubert, Kristina Lorenzen, Selin Yazici, Eckhard Mandelkow, Susanne Wegmann, Christian Betzel
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Tau is an intrinsically disordered neuronal protein in the central nervous system. Aggregated Tau is the main component of neurofibrillary tangles observed in Alzheimer’s disease. In vitro, Tau aggregation can be triggered by polyanionic c
Externí odkaz:
https://doaj.org/article/3a8096f753d74d81b89c1098d73793e0
Autor:
Susanna Gevorgyan, Robin Schubert, Sven Falke, Kristina Lorenzen, Karen Trchounian, Christian Betzel
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract In recent years silver nanoparticles (Ag NPs) gained increased and widespread applications in various fields of industry, technology, and medicine. This study describes the green synthesis of silver nanoparticles (Ag NPs) applying a low-mole
Externí odkaz:
https://doaj.org/article/e77b710f2cd0484588ef69ebe168c274
Autor:
Vasundara Srinivasan, Hévila Brognaro, Prince R. Prabhu, Edmarcia Elisa de Souza, Sebastian Günther, Patrick Y. A. Reinke, Thomas J. Lane, Helen Ginn, Huijong Han, Wiebke Ewert, Janina Sprenger, Faisal H. M. Koua, Sven Falke, Nadine Werner, Hina Andaleeb, Najeeb Ullah, Bruno Alves Franca, Mengying Wang, Angélica Luana C. Barra, Markus Perbandt, Martin Schwinzer, Christina Schmidt, Lea Brings, Kristina Lorenzen, Robin Schubert, Rafael Rahal Guaragna Machado, Erika Donizette Candido, Danielle Bruna Leal Oliveira, Edison Luiz Durigon, Stephan Niebling, Angelica Struve Garcia, Oleksandr Yefanov, Julia Lieske, Luca Gelisio, Martin Domaracky, Philipp Middendorf, Michael Groessler, Fabian Trost, Marina Galchenkova, Aida Rahmani Mashhour, Sofiane Saouane, Johanna Hakanpää, Markus Wolf, Maria Garcia Alai, Dusan Turk, Arwen R. Pearson, Henry N. Chapman, Winfried Hinrichs, Carsten Wrenger, Alke Meents, Christian Betzel
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
Three natural phenolic compounds are found to bind to an allosteric site in SARS-CoV-2 papain-like protease and exhibit antiviral activity in vitro, showing potential as starting scaffolds for drug design.
Externí odkaz:
https://doaj.org/article/94a6b8437953446b80663a578e6c235a
Autor:
Susanna Gevorgyan, Robin Schubert, Mkrtich Yeranosyan, Lilit Gabrielyan, Armen Trchounian, Kristina Lorenzen, Karen Trchounian
Publikováno v:
AMB Express, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract The application of green synthesis in nanotechnology is growing day by day. It’s a safe and eco-friendly alternative to conventional methods. The current research aimed to study raw royal jelly’s potential in the green synthesis of silve
Externí odkaz:
https://doaj.org/article/3fa9a8af0e7d42a7afdddaaf780a77b4
Autor:
Wiebke Ewert, Sebastian Günther, Francesca Miglioli, Sven Falke, Patrick Y. A. Reinke, Stephan Niebling, Christian Günther, Huijong Han, Vasundara Srinivasan, Hévila Brognaro, Julia Lieske, Kristina Lorenzen, Maria M. Garcia-Alai, Christian Betzel, Mauro Carcelli, Winfried Hinrichs, Dominga Rogolino, Alke Meents
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
The papain-like protease (PLpro) of SARS-CoV-2 is essential for viral propagation and, additionally, dysregulation of the host innate immune system. Using a library of 40 potential metal-chelating compounds we performed an X-ray crystallographic scre
Externí odkaz:
https://doaj.org/article/5abf90b91d214accbdd2fa885322f8ed
Autor:
Mengying Wang, Roland Thuenauer, Robin Schubert, Susanna Gevorgyan, Kristina Lorenzen, Hévila Brognaro, Christian Betzel
Publikováno v:
Soft Matter. 19:1363-1372
Pulsed electric fields (EFs) and a NaCl gradient induce the formation of ordered mesoscopic Alpha-Synuclein (ASN) assemblies with red-shifted emission wavelengths and thermostability.
Autor:
Amirhossein Kardoost, Robert Schönherr, Carsten Deiter, Lars Redecke, Kristina Lorenzen, Joachim Schulz, Iñaki de Diego
In cellulocrystallization is a rarely occurring event in nature. Recent advances, making use of heterologous overexpression, can promote the intracellular formation of protein crystals, but new tools are required to detect and to characterize these t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa5cd92f89a518f8a2a1ffe2b0434392
https://doi.org/10.1101/2023.03.28.533948
https://doi.org/10.1101/2023.03.28.533948
Autor:
Mohammad Vakili, Huijong Han, Christina Schmidt, Agnieszka Wrona, Marco Kloos, Iñaki de Diego, Katerina Dörner, Tian Geng, Chan Kim, Faisal Koua, Diogo Melo, Mathieu Rappas, Adam Round, Ekaterina Round, Marcin Sikorski, Joana Valerio, Tiankun Zhou, Kristina Lorenzen, Joachim Schulz
Time-resolved crystallography enabled the visualization of protein molecular motion during reaction. While light is commonly used to initiate reactions in time-resolved crystallography, only a small number of proteins can in fact be activated by ligh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77a6c80d46f30382cc1ce84be0368a47
https://doi.org/10.1101/2022.11.23.517685
https://doi.org/10.1101/2022.11.23.517685