Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kristina L. Brzoza-Lewis"'
Autor:
Sushma Kaul, Hao Xu, Manal Zabalawi, Elisa Maruko, Brian E. Fulp, Theresa Bluemn, Kristina L. Brzoza‐Lewis, Mark Gerelus, Ranjuna Weerasekera, Rachel Kallinger, Roland James, Yi (Sherry) Zhang, Michael J. Thomas, Mary G. Sorci‐Thomas
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 11 (2016)
BackgroundAtherosclerosis is a chronic inflammatory disorder whose development is inversely correlated with high‐density lipoprotein concentration. Current therapies involve pharmaceuticals that significantly elevate plasma high‐density lipoprote
Externí odkaz:
https://doaj.org/article/a33c31fe04944af48f938752dc8a1d56
Autor:
Michael J. Thomas, Rachel Kallinger, Mary G. Sorci-Thomas, Hao Xu, Brian Fulp, Yi Sherry Zhang, Theresa Bluemn, Ranjuna Weerasekera, Roland James, Manal Zabalawi, Kristina L. Brzoza-Lewis, Sushma Kaul, Elisa Maruko, Mark Gerelus
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Atherosclerosis is a chronic inflammatory disorder whose development is inversely correlated with high‐density lipoprotein concentration. Current therapies involve pharmaceuticals that significantly elevate plasma high‐density lipoprot
Autor:
Amy L. Olex, Elizabeth M. Hiltbold, Kristina L. Brzoza-Lewis, William H. Turkett, Jacquelyn S. Fetrow
Dendritic cell (DC) maturation involves widespread changes in cellular function and gene expression. The regulatory role of IFNAR in the program of DC maturation remains incompletely defined. Thus, the time evolution impact of IFNAR on this process w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f9be1f2b371dfd47459a198b07a7cd5
https://europepmc.org/articles/PMC4892211/
https://europepmc.org/articles/PMC4892211/
Autor:
Elizabeth M. Hiltbold, Maryam Ahmed, Shelby Puckett, Kristina L. Brzoza-Lewis, Douglas S. Lyles, Latoya M. Mitchell
Publikováno v:
Journal of Virology. 83:2962-2975
Wild-type (wt) vesicular stomatitis virus (VSV) strains stimulate plasmacytoid dendritic cells (pDC) through Toll-like receptor 7 (TLR7) and its adaptor molecule, MyD88. Granulocyte-macrophage colony-stimulating factor-derived DC (G-DC), which do not
Autor:
Kristina L. Brzoza-Lewis, Latoya M. Mitchell, Elizabeth M. Hiltbold, Curtis J. Henry, David A. Ornelles
Publikováno v:
The Journal of Immunology. 181:8576-8584
IL-12 family members are an important link between innate and adaptive immunity. IL-12 drives Th1 responses by augmenting IFN-γ production, which is key for clearance of intracellular pathogens. IL-23 promotes the development of IL-17-producing CD4+
Autor:
Kristina L Brzoza-Lewis, Manal Zabalawi, Ashley J Wilhelm, John S Owen, Brian Fulp, Mark Gerelus, Daniel Ferguson, Michael J Thomas, Mary Sorci-Thomas
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 32
Previous publications from our laboratory show that cholesterol-fed LDLr-/-, apoA-I -/- (DKO) mice develop accelerated atherosclerosis, as well as, a severe autoimmune disorder not seen in diet-fed LDLr -/- mice (SKO). This phenotype is characterized
Publikováno v:
Cellular immunology. 273(1)
Type I IFN is key to the immune response to viral pathogens, however its role in bacterial infections is less well understood. Mice lacking the type I IFN receptor (IFNAR−/−) demonstrate enhanced resistance to infection with Listeria monocytogene
Autor:
Latoya M. Mitchell, Kristina L. Brzoza-Lewis, Jason M. Grayson, Curtis J. Henry, Elizabeth M. Hiltbold, Marlena M. Westcott
To determine the relative contributions of DC subsets in the development of protective immunity to Listeria monocytogenes we examined the relationship between maturation, bacterial burden, and T cell priming capacity of four well characterized subset
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fb3338db9dd993e03da540516724604
https://europepmc.org/articles/PMC3078036/
https://europepmc.org/articles/PMC3078036/
Autor:
Curtis J. Henry, Elizabeth M. Hiltbold, Jason M. Grayson, Marlena M. Westcott, Anne S. Cook, Kristina L. Brzoza-Lewis, Latoya M. Mitchell
Publikováno v:
Cellular immunology. 264(1)
Listeria monocytogenes infection induces a strong inflammatory response characterized by the production of IL-12 and IFN-gamma and protective immunity against this pathogen is dependent on CD8+ T cells (CTL). Recent studies have suggested that these