Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kristina Jonsson-Schmunk"'
Publikováno v:
Expert Rev Vaccines
OBJECTIVE: Infectious disease emergencies like the 2013-2016 Ebola epidemic and the 2009 influenza and current SARS-CoV-2 pandemics illustrate that vaccines are now given to diverse populations with preexisting pathologies requiring pharmacological m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::794304abb1791ede7fb7fa139b42d1b4
https://doi.org/10.1080/14760584.2021.1899818
https://doi.org/10.1080/14760584.2021.1899818
Publikováno v:
Journal of Pharmaceutical Investigation. 48:113-134
Hepatic cytochrome P450 3A4 (CYP3A4) is an important drug-metabolizing enzyme as it is responsible for metabolizing over 30% of currently marketed drugs across most therapeutic classes. CYP3A4 is regulated at various stages including transcriptional,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d558b9825b2920c83dbe85b1be1e18b7
https://doi.org/10.1007/s40005-017-0376-y
https://doi.org/10.1007/s40005-017-0376-y
Autor:
Shellie M. Callahan, Kristina Jonsson-Schmunk, Jin Huk Choi, Maria A. Croyle, Piynauch Wonganan
Publikováno v:
Drug Metabolism and Disposition. 44:758-770
Landmark studies describing the effect of microbial infection on the expression and activity of hepatic CYP3A used bacterial lipopolysaccharide as a model antigen. Our efforts to determine whether these findings were translatable to viral infections
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a14864e7b47c619159dacd205f1ca15
https://doi.org/10.1124/dmd.115.068874
https://doi.org/10.1124/dmd.115.068874
Publikováno v:
Future Virology. 10:659-662
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44e5786b6b4f8106f83a2c5f2d86c0c5
https://doi.org/10.2217/fvl.15.25
https://doi.org/10.2217/fvl.15.25
Autor:
Jim Strong, Jin Huk Choi, Gary Wong, Alexander Bello, Jason X. Xu, Irnela Bajrovic, David B. Weiner, Xiangguo Qiu, Jonathan Audet, Kelly L. Michie, Stephen C. Schafer, Gary P. Kobinger, Mark J. Myers, Devon J. Shedlock, Lisa Fernando, Maria A. Croyle, Kristina Jonsson-Schmunk, Lilian Q. Tran
Publikováno v:
Molecular Pharmaceutics
As the Ebola outbreak in West Africa continues and cases appear in the United States and other countries, the need for long-lasting vaccines to preserve global health is imminent. Here, we evaluate the long-term efficacy of a respiratory and sublingu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cb13c9259debda55d53823f46aba435
https://doi.org/10.1021/mp500646d
https://doi.org/10.1021/mp500646d
Autor:
Shellie M. Callahan, Jin Huk Choi, Kristina Jonsson-Schmunk, Maria A. Croyle, Piyanuch Wonganan
Publikováno v:
Drug Metabolism and Disposition. 42:1191-1201
HC-04 cells were evaluated as an in vitro model for mechanistic study of changes in the function of hepatic CYP3A during virus infection. Similar to in vivo observations, infection with a first generation recombinant adenovirus significantly inhibite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a7c09bc837968e4e86fe45ce605c82c
https://doi.org/10.1124/dmd.113.056663
https://doi.org/10.1124/dmd.113.056663
Publikováno v:
Expert review of anti-infective therapy. 13(5)
In response to the severity and scale of the 2014 Ebola outbreak, several experimental vaccines were granted fast-track status for clinical testing. While they may provide long-lasting protection from Ebola, they are, in their current states, far fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8de89aaec9d4ef9e18ba630bd474a8c7
https://pubmed.ncbi.nlm.nih.gov/25796987
https://pubmed.ncbi.nlm.nih.gov/25796987