DOG1 is commonly expressed in pancreatic adenocarcinoma but unrelated to cancer aggressiveness

Autor: Kristina Jansen, Franziska Büscheck, Katharina Moeller, Martina Kluth, Claudia Hube-Magg, Niclas Christian Blessin, Daniel Perez, Jakob Izbicki, Michael Neipp, Hamid Mofid, Thies Daniels, Ulf Nahrstedt, Christoph Fraune, Frank Jacobsen, Christian Bernreuther, Patrick Lebok, Guido Sauter, Ria Uhlig, Waldemar Wilczak, Ronald Simon, Stefan Steurer, Eike Burandt, Andreas Marx, Till Krech, Till Clauditz

Publikováno v: PeerJ, Vol 9, p e11905 (2021)

Background DOG1 (ANO1; TMEM16A) is a voltage-gated calcium-activated chloride and bicarbonate channel. DOG1 is physiologically expressed in Cajal cells, where it plays an important role in regulating intestinal motility and its expression is a diagno

Externí odkaz: https://doaj.org/article/c56ee45d819c4c58ac706654267d12da

Mesothelin Expression in Human Tumors: A Tissue Microarray Study on 12,679 Tumors

Autor: Sören Weidemann, Pauline Gagelmann, Natalia Gorbokon, Maximilian Lennartz, Anne Menz, Andreas M. Luebke, Martina Kluth, Claudia Hube-Magg, Niclas C. Blessin, Christoph Fraune, Katharina Möller, Christian Bernreuther, Patrick Lebok, Till S. Clauditz, Frank Jacobsen, Jakob R. Izbicki, Kristina Jansen, Guido Sauter, Ria Uhlig, Waldemar Wilczak, Stefan Steurer, Sarah Minner, Eike Burandt, Rainer H. Krech, David Dum, Till Krech, Andreas H. Marx, Ronald Simon

Publikováno v: Biomedicines, Vol 9, Iss 4, p 397 (2021)

Mesothelin (MSLN) represents an attractive molecule for targeted cancer therapies. To identify tumors that might benefit from such therapies, tissue microarrays including 15,050 tumors from 122 different tumor types and 76 healthy organs were analyze

Externí odkaz: https://doaj.org/article/3704856d07f04207976e007df1de88dd

Worldwide Techniques and Outcomes in Robot-assisted Minimally Invasive Esophagectomy (RAMIE): Results From the Multicenter International Registry

Autor: Paolo Strignano, Jens-Peter Hölzen, Matthias Biebl, Paul Turner, Jan-Hendrik Egberts, Ivan Cecconello, Boudewijn van Etten, Suzanne S. Gisbertz, Elena Mazza, Christiane J. Bruns, Frank Benedix, Philippe Rouanet, B. Feike Kingma, Jan Willem Haveman, Peter P. Grimminger, Marc J. van Det, Michal Hubka, Johann Pratschke, Shannon M. Chan, Myles Smith, Ewout A. Kouwenhoven, Mark I. van Berge Henegouwen, Rubens Antonio Aissar Sallum, Inderpal S. Sarkaria, Kish Pursnani, Donald E. Low, Jelle P. Ruurda, Yin-Kai Chao, Hans F. Fuchs, Daniel Perez, James D. Luketich, Pieter C. van der Sluis, Chun-Yi Tsai, Richard van Hillegersberg, A. Mourregot, Philip Wai Yan Chiu, Kristina Jansen, Asif Chaudry

Publikováno v: Annals of surgery, 276(5), e386-e392. Lippincott Williams and Wilkins
Annals of Surgery, 276(5), e386-e392. LIPPINCOTT WILLIAMS & WILKINS
Annals of Surgery, 276(5), e386-e392. Lippincott Williams & Wilkins
Annals of Surgery, 276(5), e386-e392. Lippincott Williams and Wilkins
UGIRA Study Group 2022, ' Worldwide Techniques and Outcomes in Robot-assisted Minimally Invasive Esophagectomy (RAMIE) : Results From the Multicenter International Registry ', Annals of Surgery, vol. 276, no. 5, pp. e386-e392 . https://doi.org/10.1097/SLA.0000000000004550

OBJECTIVE: This international multicenter study by the Upper GI International Robotic Association aimed to gain insight in current techniques and outcomes of RAMIE worldwide.BACKGROUND: Current evidence for RAMIE originates from single-center studies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de2c413654cf51255838bffe4c18391e
https://pure.amc.nl/en/publications/worldwide-techniques-and-outcomes-in-robotassisted-minimally-invasive-esophagectomy-ramie(056e69d5-5ac4-4c5d-8c35-1aaf1f481b16).html

DOG1 overexpression is associated with mismatch repair deficiency and BRAF mutations but unrelated to cancer progression in colorectal cancer

Autor: Kristina, Jansen, Martina, Kluth, Niclas C, Blessin, Claudia, Hube-Magg, Michael, Neipp, Hamid, Mofid, Hannes, Lárusson, Thies, Daniels, Christoph, Isbert, Stephan, Coerper, Daniel, Ditterich, Holger, Rupprecht, Albert, Goetz, Christian, Bernreuther, Guido, Sauter, Ria, Uhlig, Waldemar, Wilczak, Ronald, Simon, Stefan, Steurer, Eike, Burandt, Daniel, Perez, Jakob R, Izbicki, Frank, Jacobsen, Till S, Clauditz, Andreas H, Marx, Till, Krech

Publikováno v: Histology and histopathology. 37(8)

The transmembrane channel protein DOG1 (Discovered on GIST1) is normally expressed in the gastrointestinal interstitial cells of Cajal and also in gastrointestinal stroma tumors arising from these cells. However, there is also evidence for a relevant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8dae8724fb86b7d2add06238b3f7f442
https://pubmed.ncbi.nlm.nih.gov/35642329

Mesothelin Expression in Human Tumors: A Tissue Microarray Study on 12,679 Tumors

Autor: Ronald Simon, Maximilian Lennartz, Till Krech, Ria Uhlig, Anne Menz, Patrick Lebok, Waldemar Wilczak, Kristina Jansen, Sören Weidemann, Niclas C Blessin, Guido Sauter, Till S. Clauditz, Natalia Gorbokon, David Dum, Andreas M. Luebke, Eike Burandt, Rainer Krech, Frank Jacobsen, Andreas H. Marx, Stefan Steurer, Martina Kluth, Pauline Gagelmann, Christian Bernreuther, Katharina Möller, Christoph Fraune, Sarah Minner, Jakob R. Izbicki, Claudia Hube-Magg

Publikováno v: Biomedicines
Biomedicines, Vol 9, Iss 397, p 397 (2021)
Volume 9
Issue 4

Mesothelin (MSLN) represents an attractive molecule for targeted cancer therapies. To identify tumors that might benefit from such therapies, tissue microarrays including 15,050 tumors from 122 different tumor types and 76 healthy organs were analyze

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9a00b93cfadeecab7889b21e0f53318
http://europepmc.org/articles/PMC8067734