Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kristina J. Allan"'
Publikováno v:
Oncolytic Virotherapy, Vol 2016, Iss Issue 1, Pp 15-25 (2016)
Oncolytic Virotherapy
Oncolytic Virotherapy
KJ Allan,1,2 David F Stojdl,1–3 SL Swift1 1Children’s Hospital of Eastern Ontario (CHEO) Research Institute, 2Department of Biology, Microbiology and Immunology, 3Department of Pediatrics, University of Ottawa, Ottawa, ON, Canada Abstract: High-t
Publikováno v:
Journal of visualized experiments : JoVE. (134)
High-throughput genome-wide RNAi (RNA interference) screening technology has been widely used for discovering host factors that impact virus replication. Here we present the application of this technology to uncovering host targets that specifically
Autor:
Ahmed Mamai, Susanna Grönberg, Rima Al-awar, Tommy Alain, Stephen Baird, David Uehling, Douglas J. Mahoney, Jan Brun, David F. Stojdl, Methvin Isaac, Ahmed Aman, Charles Lefebvre, Mikael Prakesh, Theresa Falls, Cina A. Sanaei, Brian J. Wilson, Nelson Pearce, Kristina J. Allan
Publikováno v:
Cancer Cell. 20:443-456
SummaryTo identify therapeutic opportunities for oncolytic viral therapy, we conducted genome-wide RNAi screens to search for host factors that modulate rhabdoviral oncolysis. Our screens uncovered the endoplasmic reticulum (ER) stress response pathw