Výsledky vyhledávání - "Kristina I. Wikstrom"

Table S1 from A Phase I/IIa Trial Using CD19-Targeted Third-Generation CAR T Cells for Lymphoma and Leukemia

Autor: Angelica Loskog, Hans Hagberg, Malcolm K. Brenner, Gianpietro Dotti, Martin Höglund, Helene Hallböök, Barbara Savoldo, Magnus Essand, Kristina I. Wikstrom, Rose Marie Amini, Tanja Lövgren, Jessica Wenthe, Gustav Gammelgård, Hannah Karlsson, Gunilla Enblad

Detailed description of the patients and infused cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24cea2ade46182d919b8d13964d044fc
https://doi.org/10.1158/1078-0432.22468122

Zobrazit plný text záznamu

Figure S1 from A Phase I/IIa Trial Using CD19-Targeted Third-Generation CAR T Cells for Lymphoma and Leukemia

Manufactured CAR batches were analyzed for the presence of CAR T cells and phenotyped for different markers as indicated in the Figure

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a3175a6f1548d3653de8fceec1f0553
https://doi.org/10.1158/1078-0432.22468128

Zobrazit plný text záznamu

Data from A Phase I/IIa Trial Using CD19-Targeted Third-Generation CAR T Cells for Lymphoma and Leukemia

Purpose:The chimeric antigen receptor (CAR) T-cell therapy has been effective for patients with CD19+ B-cell malignancies. Most studies have investigated the second-generation CARs with either CD28 or 4-1BB costimulatory domains in the CAR receptor.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57f353021e83d8a58cf0249991c17972
https://doi.org/10.1158/1078-0432.c.6526845

Zobrazit plný text záznamu

Figure S2 from A Phase I/IIa Trial Using CD19-Targeted Third-Generation CAR T Cells for Lymphoma and Leukemia

Patient plasma prior to CAR treatment (pre) and at three time points post CAR infusion was analyzed by Proseek multiplex proteomics

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95bf9166673c5ac29e01305a853e4bb8
https://doi.org/10.1158/1078-0432.22468125.v1

Zobrazit plný text záznamu

Complete Remission with Reduction of High-Risk Clones following Haploidentical NK-Cell Therapy against MDS and AML

Publikováno v: Clinical Cancer Research. 24:1834-1844

Purpose: To evaluate the safety, efficacy, and immunobiological correlates of allogeneic NK-cell–based therapy in primary chemotherapy-refractory or relapsed high-risk myelodysplastic syndrome (MDS), secondary AML (MDS/AML), and de novo AML patient

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::764612f6fa568b1f463e11fe6f8ec0b5
https://doi.org/10.1158/1078-0432.ccr-17-3196

Zobrazit plný text záznamu

A Phase I/IIa Trial Using CD19-Targeted Third-Generation CAR T Cells for Lymphoma and Leukemia

Autor: Gunilla Enblad, Hans Hagberg, Hannah Karlsson, Angelica Loskog, Barbara Savoldo, Tanja Lövgren, Martin Höglund, Magnus Essand, Kristina I. Wikstrom, Gustav Gammelgård, Rose-Marie Amini, Gianpietro Dotti, Helene Hallböök, Malcolm K. Brenner, Jessica Wenthe

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 24(24)

Purpose: The chimeric antigen receptor (CAR) T-cell therapy has been effective for patients with CD19+ B-cell malignancies. Most studies have investigated the second-generation CARs with either CD28 or 4-1BB costimulatory domains in the CAR receptor.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c3791038ba98b9466bf2a1512229a1f
https://pubmed.ncbi.nlm.nih.gov/30097433

Zobrazit plný text záznamu

748. A Clinical Trial Using Third Generation CD19 Targeting CAR T Cells for Relapsed Lymphoma and Leukemia

Autor: Angelica Loskog, Barbara Savoldo, Gunilla Enblad, Hans Hagberg, Kristina I. Wikstrom, Gianpietro Dotti, Magnus Essand, Jessica Wenthe, Helene Hallböök, Martin Höglund, Hannah Karlsson, Malcolm K. Brenner

Publikováno v: Molecular Therapy. 24:S295-S296

A Clinical Trial Using Third Generation CD19 Targeting CAR T Cells for Relapsed Lymphoma and Leukemia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d443fc70a3d0f2157070b7ca619b5d38
https://doi.org/10.1016/s1525-0016(16)33556-0

Zobrazit plný text záznamu

Abstract A041: CD19-targeting third generation CAR T cells for relapsed and refractory lymphoma and leukemia – report from the Swedish phase I/IIa trial

Autor: Kristina I. Wikstrom, Gianpietro Dotti, Barbara Savoldo, Gunilla Enblad, Hans Hagberg, Martin Höglund, Hannah Karlsson, Magnus Essand, Angelica Loskog, Malcolm K. Brenner

Publikováno v: Cancer Immunology Research. 4:A041-A041

Chimeric antigen receptor (CAR) T cells have shown promising results in patients with B cell malignancy. In preclinical studies we showed that CD19-targeting third generation (3G) CAR T cells containing signaling domains from both CD28 and 4-1BB as c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::001270adba20c9ef8d38351c86f1a74c
https://doi.org/10.1158/2326-6074.cricimteatiaacr15-a041

Zobrazit plný text záznamu

Third Generation CD19-CAR T Cells for Relapsed and Refractory Lymphoma and Leukemia Report from the Swedish Phase I/IIa Trial

Autor: Gianpietro Dotti, Barbara Savoldo, Angelica Loskog, Hannah Karlsson, Kristina I. Wikstrom, Martin Höglund, Magnus Essand, Gunilla Enblad, Hans Hagberg, Malcolm K. Brenner, Helene Hallböök

Publikováno v: Blood. 126:1534-1534

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2b1cf5acaab663cd1a5dc50ac1f6c647
https://doi.org/10.1182/blood.v126.23.1534.1534

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání