Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Kristina I. Bostrom"'
Autor:
Pallavi Mukherjee, Greg Hough, Arnab Chattopadhyay, Mohamad Navab, Hannah R. Fogelman, David Meriwether, Kevin Williams, Steven Bensinger, Travis Moller, Kym F. Faull, Aldons J. Lusis, M. Luisa Iruela-Arispe, Kristina I. Bostrom, Peter Tontonoz, Srinivasa T. Reddy, Alan M. Fogelman
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 8, Pp 1636-1647 (2017)
Feeding LDL receptor (LDLR)-null mice a Western diet (WD) increased the expression of IFN-β in jejunum as determined by quantitative RT-PCR (RT-qPCR), immunohistochemistry (IHC), and ELISA (all P < 0.0001). WD also increased the expression of choles
Externí odkaz:
https://doaj.org/article/75de2f787cb5457d800af42d09707286
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42
Obesity is a world-wide problem; an estimated 38% of the world population will be overweight and 20% will be obese by 2030. Brown adipose tissue (BAT) is a thermogenic tissue that plays an important role in energy expenditure and glucose uptake. It i
Autor:
Aradhana Verma, Gregg C Fonarow, Jeffrey J Hsu, Cynthia Jackevicius, Freny Mody, Omid Amidi, Sarah Goldberg, Deepti Upparapalli, Kleanthis Theodoropoulos, Donald Chang, Kristina I Bostrom, Andrew D Althouse, Boback Ziaeian
Publikováno v:
Circulation: Cardiovascular Quality and Outcomes. 15
Heart failure is a leading diagnosis for hospitalization with a high risk of readmission. Despite robust data and recommendations by professional societies, there is a well-documented gap in delivering guideline-directed medical therapy (GDMT) known
Autor:
Daoqin Zhang, Jiayi Yao, Xiuju Wu, Xiaojing Qiao, Li Zhang, Jocelyn Ma, Xinjiang Cai, Kristina I Bostrom, Yucheng Yao
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 41
Transitions between cell fates commonly occur in development and disease. However, reversing an unwanted cell transition in order to treat disease remains an unexplored area. Here, we report a successful process of guiding ill-fated transitions towar
Autor:
Daoqin Zhang, Xiaojing Qiao, Jiayi Yao, Xiuju Wu, Xinjiang Cai, Jocelyn A Ma, Kristina I Bostrom, Yucheng Yao
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 41
Vascular calcification is present in most people over 60 years of age and results in severe complications that increase all-cause mortality of cardiovascular disease, diabetes mellitus and chronic kidney disease. Previous studies demonstrated that en
Autor:
Xiaojing Qiao, Daoqin Zhang, Li Zhang, Jiayi Yao, Xiuju Wu, Xinjiang Cai, Kristina I Bostrom, Yucheng Yao
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 41
Cerebral arteriovenous malformations (AVMs) are the common vascular malformations that tend to rupture and cause hemorrhagic strokes. Disruptions in the integrity of vascular endothelium and endothelial cell (EC) differentiation give rise to the form
Publikováno v:
International journal of cell science & molecular biology
Multipotent cells derived from white mature adipocytes, referred to as dedifferentiated fat (DFAT) cells have the capacity differentiate into endothelial cells. The objective of this study was to modify the isolation method for DFAT cells in order to
Autor:
Li Zhang, Xinjiang Cai, Feiyang Ma, Xiaojing Qiao, Jaden Ji, Jocelyn A. Ma, Laurent Vergnes, Yan Zhao, Yucheng Yao, Xiuju Wu, Kristina I. Boström
Publikováno v:
Molecular Metabolism, Vol 80, Iss , Pp 101870- (2024)
Objective: Bone morphogenetic protein (BMP) signaling is intricately involved in adipose tissue development. BMP7 together with BMP4 have been implicated in brown adipocyte differentiation but their roles during development remains poorly specified.
Externí odkaz:
https://doaj.org/article/4b6bce9c61ab44ff9f6ee04560606c60
Autor:
Simon T. Hui, Lili Gong, Chantle Swichkow, Montgomery Blencowe, Dorota Kaminska, Graciel Diamante, Calvin Pan, Meet Dalsania, Samuel W. French, Clara E. Magyar, Päivi Pajukanta, Jussi Pihlajamäki, Kristina I. Boström, Xia Yang, Aldons J. Lusis
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 16, Iss 6, Pp 943-960 (2023)
Background & Aims: Nonalcoholic steatohepatitis (NASH) is a complex disease involving both genetic and environmental factors in its onset and progression. We analyzed NASH phenotypes in a genetically diverse cohort of mice, the Hybrid Mouse Diversity
Externí odkaz:
https://doaj.org/article/17f948e14a694036a2a9724de594eb98
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Multipotent cells derived from white adipose tissue have been shown to differentiate into multiple lineages including neurogenic lineages. However, the high innervation of brown adipose tissue by the sympathetic nervous system suggest it mig
Externí odkaz:
https://doaj.org/article/580ad43ef79f44f789207199c9680d07