Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Kristina Forsterová"'
Complex genetic and histopathological study of 15 patient-derived xenografts of aggressive lymphomas
Autor:
Radek Jakša, Jana Karolová, Michael Svatoň, Dmitry Kazantsev, Martina Grajciarová, Eva Pokorná, Zbyněk Tonar, Magdalena Klánová, Lucie Winkowska, Diana Maláriková, Petra Vočková, Kristina Forsterová, Nicol Renešová, Alexandra Dolníková, Kristýna Nožičková, Pavel Dundr, Eva Froňková, Marek Trněný, Pavel Klener
Publikováno v:
Laboratory Investigation. 102:957-965
Non-Hodgkin lymphomas (NHL) represent the most common hematologic malignancies. Patient-derived xenografts (PDXs) are used for various aspects of translational research including preclinical in vivo validation of experimental treatment approaches. Wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4376d6c672b99e78da472164a66fbbc
https://doi.org/10.1038/s41374-022-00784-w
https://doi.org/10.1038/s41374-022-00784-w
Publikováno v:
Scopus-Elsevier
Ellipticine is a potent antineoplastic agent, whose mode of action is considered to be based mainly on DNA intercalation and/or inhibition of topoisomerase II. Since we found that ellipticine also forms the cytochrome P450 (CYP)-mediated covalent DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::046ba437af749e2a72cc65afb3c12db4
https://doi.org/10.5507/bp.2005.078
https://doi.org/10.5507/bp.2005.078