Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Kristina Djinović Carugo"'
Publikováno v:
Crystals, Vol 14, Iss 5, p 443 (2024)
The B-factor, also known as the atomic displacement parameter, is a fundamental metric in crystallography for quantifying the positional flexibility of atoms within crystal lattices. In structural biology, various developments have expanded the use o
Externí odkaz:
https://doaj.org/article/dbaaecfae79b47ab8b77a2d5789264e4
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Protein structure prediction and structural biology have entered a new era with an artificial intelligence-based approach encoded in the AlphaFold2 and the analogous RoseTTAfold methods. More than 200 million structures have been predicted by AlphaFo
Externí odkaz:
https://doaj.org/article/fc8236601e3d4221978b779ace9231dc
Publikováno v:
PLoS Biology, Vol 21, Iss 6, p e3002187 (2023)
In the past 2 decades, structural biology has transformed from a single technique used on single proteins to a multimodal integrative approach. Recently, protein structure prediction algorithms have opened new avenues to address challenging biologica
Externí odkaz:
https://doaj.org/article/1e79edb54086453f94f0da401b797445
Autor:
Julius Kostan, Miha Pavšič, Vid Puž, Thomas C Schwarz, Friedel Drepper, Sibylle Molt, Melissa Ann Graewert, Claudia Schreiner, Sara Sajko, Peter F M van der Ven, Adekunle Onipe, Dmitri I Svergun, Bettina Warscheid, Robert Konrat, Dieter O Fürst, Brigita Lenarčič, Kristina Djinović-Carugo
Publikováno v:
PLoS Biology, Vol 19, Iss 4, p e3001148 (2021)
Sarcomeres, the basic contractile units of striated muscle cells, contain arrays of thin (actin) and thick (myosin) filaments that slide past each other during contraction. The Ig-like domain-containing protein myotilin provides structural integrity
Externí odkaz:
https://doaj.org/article/bb2463d4a4ee4d459292729c75f411ce
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Myotilin is a component of the sarcomere where it plays an important role in organisation and maintenance of Z-disk integrity. This involves direct binding to F-actin and filamin C, a function mediated by its Ig domain pair. While the struct
Externí odkaz:
https://doaj.org/article/c9ab95b6f7574c8ab9cb2d8daa190733
Autor:
Gustavo Arruda Bezerra, Yuko Ohara-Nemoto, Irina Cornaciu, Sofiya Fedosyuk, Guillaume Hoffmann, Adam Round, José A. Márquez, Takayuki K. Nemoto, Kristina Djinović-Carugo
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Porphyromonas gingivalis and Porphyromonas endodontalis are important bacteria related to periodontitis, the most common chronic inflammatory disease in humans worldwide. Its comorbidity with systemic diseases, such as type 2 diabetes, oral
Externí odkaz:
https://doaj.org/article/1b171c954af24de4a2b197fb3e496657
Publikováno v:
Crystals, Vol 9, Iss 11, p 581 (2019)
The presence of isolated metal cations, far from any other atom, is not uncommon in protein crystal structures. A systematic survey of the Protein Data Bank showed that nearly 8% of the metal cations are naked, more frequently if they can interact on
Externí odkaz:
https://doaj.org/article/1232642cd78044d6a51fa7167d42f3c0
Autor:
Daniel Schmidt, Christian Obinger, Ilenia Serra, Sabine Van Doorslaer, Vera Pfanzagl, G. Mlynek, Paul G. Furtmüller, Stefan Hofbauer, Kristina Djinović-Carugo
Publikováno v:
Biochemistry
Biochemistry 60(8), 621-634 (2021). doi:10.1021/acs.biochem.0c00910
Biochemistry 60(8), 621-634 (2021). doi:10.1021/acs.biochem.0c00910
Biochemistry 60(8), 621 - 634 (2021). doi:10.1021/acs.biochem.0c00910
Chlorite dismutases (Clds) are heme b-containing oxidoreductases that can decompose chlorite to chloride and molecular oxygen. They are divided in two clades that differ in ol
Chlorite dismutases (Clds) are heme b-containing oxidoreductases that can decompose chlorite to chloride and molecular oxygen. They are divided in two clades that differ in ol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1c972d165fbcdf339d8c7ed0de6395a
https://doi.org/10.1021/acs.biochem.0c00910
https://doi.org/10.1021/acs.biochem.0c00910
Autor:
Sofiya Fedosyuk, Gustavo Arruda Bezerra, Katharina Radakovics, Terry K Smith, Massimo Sammito, Nina Bobik, Adam Round, Lynn F Ten Eyck, Kristina Djinović-Carugo, Isabel Usón, Tim Skern
Publikováno v:
PLoS Pathogens, Vol 12, Iss 12, p e1006079 (2016)
Vaccinia virus interferes with early events of the activation pathway of the transcriptional factor NF-kB by binding to numerous host TIR-domain containing adaptor proteins. We have previously determined the X-ray structure of the A46 C-terminal doma
Externí odkaz:
https://doaj.org/article/4120c21604904d6bbfde04d0e9cc44e4
Autor:
Herve Celia, Vadim Kotov, Oliver Vesper, Maria Garcia-Alai, Stephan Nussberger, Susan K. Buchanan, G. Mlynek, Jiri Wald, C. Loew, Celso M. Teixeira-Duarte, Marina Pletzer, João H. Morais-Cabral, Thomas C. Marlovits, Kristina Djinović-Carugo
Publikováno v:
Protein science 30(1), 201-217 (2021). doi:10.1002/pro.3986
Protein Science : A Publication of the Protein Society
Protein Science : A Publication of the Protein Society
Protein science 30(1), 201 - 217 (2021). doi:10.1002/pro.3986
Protein stability is a key factor in successful structural and biochemical research. However, the approaches for systematic comparison of protein stability are limited by sample consu
Protein stability is a key factor in successful structural and biochemical research. However, the approaches for systematic comparison of protein stability are limited by sample consu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::286fe9b9f64775e4766faec078c5cb02
https://doi.org/10.1002/pro.3986
https://doi.org/10.1002/pro.3986