Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Kristina Dietert"'
Autor:
Geraldine Nouailles, Emanuel Wyler, Peter Pennitz, Dylan Postmus, Daria Vladimirova, Julia Kazmierski, Fabian Pott, Kristina Dietert, Michael Muelleder, Vadim Farztdinov, Benedikt Obermayer, Sandra-Maria Wienhold, Sandro Andreotti, Thomas Hoefler, Birgit Sawitzki, Christian Drosten, Leif E. Sander, Norbert Suttorp, Markus Ralser, Dieter Beule, Achim D. Gruber, Christine Goffinet, Markus Landthaler, Jakob Trimpert, Martin Witzenrath
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
The immune response is key in determining disease severity of COVID19. Here Nouailles et al., apply bulk proteomics and scRNA-Seq of lung and blood samples of SARS-CoV-2 infected Syrian hamsters and provide a temporal atlas of the systemic and pulmon
Externí odkaz:
https://doaj.org/article/072ec28bf61e4f88ac379cb3aa53c111
Autor:
Cengiz Goekeri, Peter Pennitz, Wibke Groenewald, Ulrike Behrendt, Holger Kirsten, Christian M. Zobel, Sarah Berger, Gitta A. Heinz, Mir-Farzin Mashreghi, Sandra-Maria Wienhold, Kristina Dietert, Anca Dorhoi, Achim D. Gruber, Markus Scholz, Gernot Rohde, Norbert Suttorp, CAPNETZ Study Group, Martin Witzenrath, Geraldine Nouailles
Publikováno v:
Cells, Vol 12, Iss 6, p 959 (2023)
Community-acquired pneumonia remains a major contributor to global communicable disease-mediated mortality. Neutrophils play a leading role in trying to contain bacterial lung infection, but they also drive detrimental pulmonary inflammation, when dy
Externí odkaz:
https://doaj.org/article/93410f95cc3b4d118dfe8fe77acdc5af
Autor:
Sarah Berger, Cengiz Goekeri, Shishir K. Gupta, Julio Vera, Kristina Dietert, Ulrike Behrendt, Jasmin Lienau, Sandra-Maria Wienhold, Achim D. Gruber, Norbert Suttorp, Martin Witzenrath, Geraldine Nouailles
Publikováno v:
Critical Care, Vol 22, Iss 1, Pp 1-11 (2018)
Abstract Background Community-acquired pneumonia (CAP) remains a major cause of death worldwide. Mechanisms underlying the detrimental outcome despite adequate antibiotic therapy and comorbidity management are still not fully understood. Methods To m
Externí odkaz:
https://doaj.org/article/eb7de310be864aa19bb97c248e611c67
Autor:
Daniel E Demminger, Lisa Walz, Kristina Dietert, Helen Hoffmann, Oliver Planz, Achim D Gruber, Veronika vonMessling, Thorsten Wolff
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 5, Pp n/a-n/a (2020)
Abstract The current seasonal inactivated influenza vaccine protects only against a narrow range of virus strains as it triggers a dominant antibody response toward the hypervariable hemagglutinin (HA) head region. The discovery of rare broadly prote
Externí odkaz:
https://doaj.org/article/83611fcf9f514407a0ffdfe7a0ffcd4f
Autor:
Sandra-Maria Wienhold, Mario Macrì, Geraldine Nouailles, Kristina Dietert, Corinne Gurtner, Achim D Gruber, Markus M Heimesaat, Jasmin Lienau, Fabian Schumacher, Burkhard Kleuser, Bastian Opitz, Norbert Suttorp, Martin Witzenrath, Holger C Müller-Redetzky
Publikováno v:
Critical Care, Vol 22, Iss 1, Pp 1-12 (2018)
Abstract Background Antibiotic exposure alters the microbiota, which can impact the inflammatory immune responses. Critically ill patients frequently receive antibiotic treatment and are often subjected to mechanical ventilation, which may induce loc
Externí odkaz:
https://doaj.org/article/77a19fd40e1b4921aa74b0a9ef736f36
Autor:
Alexander Perniss, Nadine Schmidt, Corinne Gurtner, Kristina Dietert, Oliver Schwengers, Markus Weigel, Julia Hempe, Christa Ewers, Uwe Pfeil, Ulrich Gärtner, Achim D. Gruber, Torsten Hain, Wolfgang Kummer
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Abstract Several species of the Gram-negative genus Bordetella are the cause of respiratory infections in mammals and birds, including whooping cough (pertussis) in humans. Very recently, a novel atypical species, Bordetella pseudohinzii, was isolate
Externí odkaz:
https://doaj.org/article/a4e38a4616c9419092e411bc2705df3d
Autor:
Sandra-Maria Wienhold, Markus C. Brack, Geraldine Nouailles, Gopinath Krishnamoorthy, Imke H. E. Korf, Claudius Seitz, Sarah Wienecke, Kristina Dietert, Corinne Gurtner, Olivia Kershaw, Achim D. Gruber, Anton Ross, Holger Ziehr, Manfred Rohde, Jens Neudecker, Jasmin Lienau, Norbert Suttorp, Stefan Hippenstiel, Andreas C. Hocke, Christine Rohde, Martin Witzenrath
Publikováno v:
Viruses, Vol 14, Iss 1, p 33 (2021)
Respiratory infections caused by multidrug-resistant Acinetobacter baumannii are difficult to treat and associated with high mortality among critically ill hospitalized patients. Bacteriophages (phages) eliminate pathogens with high host specificity
Externí odkaz:
https://doaj.org/article/133b0ff03ec84f789f3f93a9994295ec
Autor:
Birgitt Gutbier, Xiaohui Jiang, Kristina Dietert, Carolin Ehrler, Jasmin Lienau, Paul Van Slyke, Harold Kim, Van C. Hoang, Jason T. Maynes, Daniel J. Dumont, Achim D. Gruber, Norbert Weissmann, Timothy J. Mitchell, Norbert Suttorp, Martin Witzenrath
Publikováno v:
Critical Care, Vol 21, Iss 1, Pp 1-12 (2017)
Abstract Background Community-acquired pneumonia (CAP) is a significant cause of morbidity and mortality worldwide. Despite effective antimicrobial therapy, CAP can induce pulmonary endothelial hyperpermeability resulting in life-threatening lung fai
Externí odkaz:
https://doaj.org/article/2bf0dc3bc5d244dca7926872831e2097
Autor:
Leonie Wallmeyer, Kristina Dietert, Michaela Sochorová, Achim D. Gruber, Burkhard Kleuser, Kateřina Vávrová, Sarah Hedtrich
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Mutations in the gene encoding for filaggrin (FLG) are major predisposing factors for atopic dermatitis (AD). Besides genetic predisposition, immunological dysregulations considerably contribute to its pathophysiology. For example, thymic st
Externí odkaz:
https://doaj.org/article/29bafae408b546e38cc4fe0bf4395f17
Autor:
Alexander N. Dabrowski, Anshu Shrivastav, Claudia Conrad, Kassandra Komma, Markus Weigel, Kristina Dietert, Achim D. Gruber, Wilhelm Bertrams, Jochen Wilhelm, Bernd Schmeck, Katrin Reppe, Philippe D. N'Guessan, Sahar Aly, Norbert Suttorp, Torsten Hain, Janine Zahlten
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Streptococcus pneumoniae is the most frequent cause of community-acquired pneumonia. Endogenous host defense molecules such as peptidoglycan recognition protein 4 (PGLYRP4) might influence the course of this disease. To the best of our knowledge, the
Externí odkaz:
https://doaj.org/article/0ab7bd817f3e44a58a6c81074992d7ed